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The Effect of Inhaled Beta-2 Agonists on Heart Rate in Patients With Asthma: Sensor-Based Observational Study

The exact timing of the use of medication was recorded using the smart inhaler by Adherium (currently available as “Hailie”; Multimedia Appendix 1). This is an inhaler add-on that records when the inhaler is used. The patient kept using their regular inhaler (including canister) prescribed by their asthma health care provider. The smart inhaler itself is a small extra “casing” for the regular inhalers.

Rishi Jayant Khusial, Jacob K Sont, Omar S Usmani, Matteo Bonini, Kian Fan Chung, Stephen James Fowler, Persijn J Honkoop

JMIR Cardio 2024;8:e56848

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A Roadmap for Using Causal Inference and Machine Learning to Personalize Asthma Medication Selection

Reference 42: Treatable traits, combination inhaler therapy and the future of asthma managementinhaler

Flory L Nkoy, Bryan L Stone, Yue Zhang, Gang Luo

JMIR Med Inform 2024;12:e56572

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Perspectives of Patients With Chronic Respiratory Diseases and Medical Professionals on Pulmonary Rehabilitation in Pune, India: Qualitative Analysis

I keep my inhaler in my pocket. If I feel breathless while on duty, I go to the washroom, use my inhaler, sit there for 5-10 minutes, and resume work. All patients had consulted multiple medical professionals about their physical symptoms.

Rashmi Padhye, Shruti D Sahasrabudhe, Mark W Orme, Ilaria Pina, Dipali Dhamdhere, Suryakant Borade, Meenakshi Bhakare, Zahira Ahmed, Andy Barton, Mahavir Modi, Dominic Malcolm, Sundeep Salvi, Sally J Singh

JMIR Form Res 2023;7:e45624

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Psychological Effects of Aromatherapy on Smokers With Depressive Tendencies During Smoking Cessation Treatment: Protocol for a Pre-Post Single-Arm Clinical Trial

An aromatherapy inhaler is a portable, plastic, lipstick-like container that houses a cotton wick soaked in essential oils. The inhaler enables users to smell the aromas without getting their hands dirty or spilling the oils. Similar “aromasticks” have been used in British hospitals to control symptoms of nausea, insomnia, and anxiety, and to induce relaxation [31,32].

Akiko Hata, Maki Komiyama, Akihiro Yasoda, Hiromichi Wada, Hajime Yamakage, Noriko Satoh-Asahara, Tatsuya Morimoto, Yuko Takahashi, Koji Hasegawa

JMIR Res Protoc 2022;11(7):e38626

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Effectiveness of the BreatheSuite Device in Assessing the Technique of Metered-Dose Inhalers: Validation Study

Nevertheless, studies have reported that up to 92% of patients with asthma demonstrate poor inhaler technique [7-9]. Sanchis et al [10] conducted a systematic review in 2016 to assess the most common errors in inhaler use among patients with asthma and those with COPD treated with MDIs. They concluded that incorrect inhaler use is unacceptably high outside clinical trials and does not seem to have improved over the past 40 years [10].

Meshari F Alwashmi, Gerald Mugford, Brett Vokey, Waseem Abu-Ashour, John Hawboldt

JMIR Biomed Eng 2021;6(4):e26556

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A Study to Investigate the Prevalence of Device-Specific Errors in Inhaler Technique in Adults With Airway Disease (The SCORES Study): Protocol for a Single Visit Prevalence Study

They will be accompanied by a member of the study research team, and the same person will both assess and correct any identified errors in the inhaler technique. The study team members will also record all relevant study data into the CRF. The participants will be asked to demonstrate their inhaler technique using a single-use placebo inhaler device. This is standard clinical practice, and placebo devices, which are identical to the inhaler, are available for all inhaler device types.

Ruth De Vos, Thomas Brown, Jayne Longstaff, Mitch Lomax, Heather Mackenzie, Alexander Hicks, Hitasha Rupani, Jessica Gates, Lauren Fox, Laura Wiffen, Anoop J Chauhan

JMIR Res Protoc 2021;10(8):e26350

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Parent Experiences With Electronic Medication Monitoring in Pediatric Asthma Management: Qualitative Study

The trial studied the effects of EMM via Bluetooth-enabled inhaler sensors, accompanied by a mobile app in pediatric asthma management [15]. Sensors tracked daily inhaler medication usage, which parents and clinicians could monitor.

Kristin Kan, Sara Shaunfield, Madeleine Kanaley, Avneet Chadha, Kathy Boon, Carolyn C Foster, Luis Morales, Patricia Labellarte, Deneen Vojta, Ruchi S Gupta

JMIR Pediatr Parent 2021;4(2):e25811

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Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial

All patients received a Smart Track device (Smartinhaler [Adherium Ltd]; Figure 1) that clipped on their ICS/LABA inhaler. Smart Track is an electronic device that allows measuring adherence to the inhalers. Each puff is recorded in the device memory. Smart Track records the date and time the inhaler was used and the number of puffs taken. Smart Track features include reminders, onscreen questions about asthma control, and medication feedback viewing online, but these have been deactivated.

Carlos Almonacid, Carlos Melero, Antolín López Viña, Carolina Cisneros, Luis Pérez de Llano, Vicente Plaza, Juan Luis García-Rivero, Auxiliadora Romero Falcón, Jacinto Ramos, Teresa Bazús González, María Andrés Prado, Alfonso Muriel