%0 Journal Article
%@ 2561-326X
%I JMIR Publications
%V 5
%N 2
%P e12218
%T Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial
%A Almonacid,Carlos
%A Melero,Carlos
%A López Viña,Antolín
%A Cisneros,Carolina
%A Pérez de Llano,Luis
%A Plaza,Vicente
%A García-Rivero,Juan Luis
%A Romero Falcón,Auxiliadora
%A Ramos,Jacinto
%A Bazús González,Teresa
%A Andrés Prado,María
%A Muriel,Alfonso
%+ Department of Respiratory Medicine, Instituto Ramón y Cajal de Investigación Sanitaria, University of Alcala de Henares, Ctra. De Colmenar Viejo, km. 9,100, Madrid, , Spain, 34 655 534 475, caralmsan@gmail.com
%K asthma
%K adherence
%K SMS
%K control
%K cell phone
%K inhaler
%K Smartinhaler
%D 2021
%7 9.2.2021
%9 Original Paper
%J JMIR Form Res
%G English
%X Background: Poor adherence to inhaled medication in asthma patients is of great concern. It is one of the main reasons for inadequate asthma control. Objective: The goal of the research was to determine if motivational messages using short message service (SMS, or text) improved adherence to inhaled medication in patients with asthma. Methods: A prospective multicenter randomized parallel-group clinical trial was conducted in 10 asthma clinics in Spain. Adherence was assessed with electronic monitors (Smartinhaler, Adherium Ltd) connected to inhalers. Patients in the SMS group received psychologist-developed motivational messages every 3 days for 6 months. Results: There were 53 patients in the SMS group and 88 patients in the control group. After 6 months, mean electronic adherence was 70% (SD 17%) in the intervention group and 69% (SD 17%) in the control group (P=.82). Significant differences between the study groups in morning and evening adherence to inhaled therapy, asthma control, exhaled nitric oxide levels, or improvement of lung functions were not observed. Conclusions: Motivational messages were not useful to improve adherence to inhaled asthma medication compared with usual care. 
%M 33560235
%R 10.2196/12218
%U http://formative.jmir.org/2021/2/e12218/
%U https://doi.org/10.2196/12218
%U http://www.ncbi.nlm.nih.gov/pubmed/33560235