JMIR Formative Research

Major depressive disorder is a leading cause of disability, and access to specialist psychiatric follow-up remains limited in many settings. Telepsychiatry may reduce logistical barriers to care, but data on video-based follow-up under routine outpatient conditions in Türkiye are scarce, and comparisons of delivery modalities are frequently limited by baseline imbalance between self-selected groups.

This cross-sectional study examined AI use among 524 health care professionals in the United States and United Kingdom, focusing on current applications, access, barriers, and factors that could support adoption. AI use was common but varied across professional and national contexts, with findings highlighting the importance of evidence, organizational guidance, training, privacy safeguards, and integration into clinical workflows for responsible adoption.

Digital mental health interventions (DMHIs) are increasingly popular for their ability to disseminate evidence-based treatments in a scalable, accessible way. Engagement with digital treatments is critical for effectiveness but remains poorly defined and measured. Most studies rely on subjective self-reports or 1 or 2 objective metrics, overlooking the multidimensional nature of how users interact with DMHIs.

Physical inactivity and insufficient muscle-strengthening exercise remain important public health concerns among adults with chronic diseases. Active video games may offer an accessible way to support exercise participation, but many may not provide sufficient exercise intensity to produce meaningful physiological responses. Ring Fit Adventure (RFA) is an active video game that combines aerobic and resistance-based exercise. However, little is known about its physiological demands among adults with chronic diseases.

Existing risk scores for nonvariceal upper gastrointestinal bleeding (NVUGIB) may not adequately represent the heterogeneity of coexisting chronic conditions. Routinely collected hospital discharge records may enable data-driven characterization of clinically meaningful comorbidity profiles.

Health care professionals in safety-net settings often rely on lengthy and inconsistently maintained community health resource lists when connecting patients with services. Bridgedd is a health care staff–facing web application designed to generate geographically and categorically filtered community resources in a unique format that makes information about each resource more accessible.

One in three young adults reported substance-related generative AI use, mainly for seeking information on substances, with higher prevalence among Black and male respondents; findings highlight that generative AI might be shaping the substance-use ecosystem among young adults and further research is needed to understand its public health implications.

Tuberculosis (TB) remains a major global health challenge, with 10.6 million new cases and 1.3 million deaths reported in 2022. Artisanal miners in sub‑Saharan Africa are particularly vulnerable due to poverty, overcrowded living conditions, and high HIV prevalence. In the Democratic Republic of Congo (DRC), TB prevalence among miners is high, yet determinants remain insufficiently studied.

Morphology-based disciplines such as histology, embryology, and cytogenetics require strong visual learning and rely heavily on visual pattern recognition, with more complex integrative processes, that is, higher-order cognitive skills that connect, interpret, and apply knowledge across contexts. These skills may be supported by social media formats. In parallel, medical students increasingly engage with digital and social media platforms, prompting interest in their potential educational value. Instagram (Meta Platforms, Inc), as an image-centered and interactive medium, has emerged as a potential pedagogical tool. The Histo.Embryo Instagram account was launched in 2023 under the auspices of the French National College of Histologists, Embryologists, and Cytogeneticists (CHEC) to complement traditional teaching with bilingual, interactive, image-based posts.

Digital nudging strategies are increasingly implemented to promote physical activity; yet, evidence from real-world fitness settings remains limited. The early membership period in fitness centers is characterized by high dropout rates, emphasizing the need for formative evaluations that clarify behavioral mechanisms underlying exercise engagement.

TikTok has become a major source of mental health information, yet concerns persist regarding the quality and reliability of psychiatric content disseminated on the platform. While misinformation has been documented for several mental disorders, no study has specifically examined how borderline personality disorder (BPD) is portrayed on TikTok.

Smoking is common in Saudi Arabia, particularly among men. Religion plays a protective role against smoking and serves as a motivator for quitting. Faith-based interventions have shown positive effects in supporting smoking cessation among Muslims who smoke; however, few studies have tested their acceptability when delivered via mobile phone messaging.