JMIR Formative Research

Sexual dysfunction (SD) is common among childhood cancer survivors, affecting approximately 20% to 50% of patients. National guidelines recommend discussions about sexuality throughout cancer care, and prior work demonstrates patient interest in SD conversations. Despite its prevalence and importance, SD is widely underrecognized and undertreated, creating gaps in comprehensive whole-person care.

Women living in rural agrarian reform communities face intersecting challenges related to social, economic, racial, and gender vulnerabilities, which significantly increase their likelihood of developing physical and mental health problems. Despite the potential of telephone-based interventions to promote mental health, there is a lack of studies assessing their feasibility and effectiveness among underserved populations in Brazil.

Parent management training (PMT) is an evidence-based intervention for children with disruptive behavior problems. However, access to care is often limited by cost, availability of clinicians, scheduling, and transportation barriers. Integrating artificial intelligence (AI) into group PMT may improve accessibility, personalization, and adherence, while preserving therapeutic quality.

China faces a high prevalence of mental disorders but low treatment uptake, a gap driven by limited awareness and unevenly distributed mental health resources. While online psychotherapy has the potential to expand access, patient willingness remains insufficiently explored.

The universal adoption of mobile technologies by households has created an opportunity to provide families with young children with access to high-quality oral health information at convenient times and locations. Using community agencies (eg, Head Start and public health programs) that offer parenting education is an effective approach to reaching families in low-income households.

Health care professionals’ perceptions of telemedicine, its usability, and the presence of organizational barriers are important determinants of the successful implementation of digital solutions in health care. In Kazakhstan, the use of international assessment instruments requires contextual adaptation. The Telehealth Usability Questionnaire-Model for Assessment of Telemedicine-Kazakhstan version (TUQ-MAST-KZ) questionnaire was previously developed and psychometrically validated by integrating elements of the TUQ and MAST frameworks to assess perceptions of telemedicine within the national context.

The widespread prevalence of chronic pain (CP) significantly impacts daily functioning worldwide. In mainland China, maintaining engagement in biopsychosocial interventions remains challenging. Gamification, designed based on self-determination theory, can enhance motivation, while machine learning (ML) algorithms can assist clinicians in dynamically optimizing pain management.

Periodontitis is a chronic gum disease affecting approximately 42% of adults aged 30 years and older in the United States. Training dental students to accurately diagnose and manage periodontitis is a critical component of dental education and clinical care. Recent advances in large language models offer new opportunities to support both domains, yet their performance in periodontal diagnosis remains largely unexplored, particularly for newer models such as GPT-5.

In recent years, large language models (LLMs) have undergone swift cycles of refinement and iteration. However, in the realm of clinical medicine, different LLMs' capability of logical reasoning and disease diagnosis needs further investigation.

Increasing life expectancy has increased focus on the health-related consequences of aging, such as sarcopenia and frailty. Given the prevalence of these conditions among older individuals and the frequent resulting long-term care needs, early detection and intervention are crucial.

Men face a substantially higher risk of suicide. Effective suicide prevention strategies for men should specifically target gender-related risk factors, such as their lower likelihood of seeking professional help.

After breast cancer, cervical cancer (CC) is one of the leading causes of female mortality. CC accounts for more than 7.5% of female cancer deaths worldwide. Human papillomavirus (HPV) is the most common sexually transmitted disease in women and the leading cause of CC in almost 99% of all CC cases. HPV vaccination could prevent up to 70% of HPV-related CC and 90% of genital warts. HPV vaccination is the bedrock of primary prevention and helps reduce the incidence and death rates of HPV-associated CC.