TY  - JOUR
AU  - Almonacid, Carlos
AU  - Melero, Carlos
AU  - López Viña, Antolín
AU  - Cisneros, Carolina
AU  - Pérez de Llano, Luis
AU  - Plaza, Vicente
AU  - García-Rivero, Juan Luis
AU  - Romero Falcón, Auxiliadora
AU  - Ramos, Jacinto
AU  - Bazús González, Teresa
AU  - Andrés Prado, María
AU  - Muriel, Alfonso
PY  - 2021
DA  - 2021/2/9
TI  - Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial
JO  - JMIR Form Res
SP  - e12218
VL  - 5
IS  - 2
KW  - asthma
KW  - adherence
KW  - SMS
KW  - control
KW  - cell phone
KW  - inhaler
KW  - Smartinhaler
AB  - Background: Poor adherence to inhaled medication in asthma patients is of great concern. It is one of the main reasons for inadequate asthma control. Objective: The goal of the research was to determine if motivational messages using short message service (SMS, or text) improved adherence to inhaled medication in patients with asthma. Methods: A prospective multicenter randomized parallel-group clinical trial was conducted in 10 asthma clinics in Spain. Adherence was assessed with electronic monitors (Smartinhaler, Adherium Ltd) connected to inhalers. Patients in the SMS group received psychologist-developed motivational messages every 3 days for 6 months. Results: There were 53 patients in the SMS group and 88 patients in the control group. After 6 months, mean electronic adherence was 70% (SD 17%) in the intervention group and 69% (SD 17%) in the control group (P=.82). Significant differences between the study groups in morning and evening adherence to inhaled therapy, asthma control, exhaled nitric oxide levels, or improvement of lung functions were not observed. Conclusions: Motivational messages were not useful to improve adherence to inhaled asthma medication compared with usual care. 
SN  - 2561-326X
UR  - http://formative.jmir.org/2021/2/e12218/
UR  - https://doi.org/10.2196/12218
UR  - http://www.ncbi.nlm.nih.gov/pubmed/33560235
DO  - 10.2196/12218
ID  - info:doi/10.2196/12218
ER  -