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In Vitro Characterization of the Immune Response to an Epitope Ensemble Vaccine Against Rhinovirus in Pediatric Asthma and Adults With Chronic Obstructive Pulmonary Disease: Protocol for an Observational and Exploratory Study

In Vitro Characterization of the Immune Response to an Epitope Ensemble Vaccine Against Rhinovirus in Pediatric Asthma and Adults With Chronic Obstructive Pulmonary Disease: Protocol for an Observational and Exploratory Study

This exploratory study protocol has been approved by the Ethical Board Committee of the Hospital Clínico San Carlos (23/799-E). The study will be conducted in accordance with the Declaration of Helsinki and Good Clinical Practice (GCP) guidelines. All participants provided their written informed consent to participate in this study. Participant confidentiality will be maintained throughout the study. All data will be anonymized during processing and stored securely.

Sara Alonso Fernandez, Raquel Reyes-Manzanas, Susana Camara, Juan Mozas-Gutierrez, Myriam Calle-Rubio, Juan Rodriguez-Hermosa, Andres Bodas-Pinedo, Santiago Rueda Esteban, Esther M Lafuente, Jesús Reiné, Pedro A Reche

JMIR Res Protoc 2025;14:e73383

Feasibility of Collecting and Linking Digital Phenotyping, Clinical, and Genetics Data for Mental Health Research: Pilot Observational Study

Feasibility of Collecting and Linking Digital Phenotyping, Clinical, and Genetics Data for Mental Health Research: Pilot Observational Study

For compensation, participants were either entered into a draw for 10 Aus $100 (US $65) e-gift cards (cohort 1) or received an Aus $50 (US $33) e-gift card (cohort 2). Three unique identifiers were randomly assigned to each participant: one upon receipt of the study invitation; one during screening; and one upon confirmation of eligibility. These identifiers enabled linkage between baseline and digital phenotyping data for participants from AGDS.

Joanne R Beames, Omar Dabash, Michael J Spoelma, Artur Shvetcov, Wu Yi Zheng, Aimy Slade, Jin Han, Leonard Hoon, Joost Funke Kupper, Richard Parker, Brittany Mitchell, Nicholas G Martin, Jill M Newby, Alexis E Whitton, Helen Christensen

JMIR Form Res 2025;9:e71377