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Associations Among Diet, Health, Lifestyle, and Gut Microbiota Composition in the General French Population: Protocol for the Le French Gut – Le Microbiote Français Study

Associations Among Diet, Health, Lifestyle, and Gut Microbiota Composition in the General French Population: Protocol for the Le French Gut – Le Microbiote Français Study

By collecting 100,000 gut microbiota profiles combined with metadata on diet, health, and lifestyle, “Le French Gut – Le Microbiote Français” aims at (1) better understanding the heterogeneity of healthy gut microbiota and its link with nutrition, lifestyle, and anthropometric characteristics and (2) predicting changes in gut microbiota associated with diseases such as chronic diseases, neurodevelopmental disorders, and neurodegenerative conditions.

Chloe Connan, Sébastien Fromentin, Mourad Benallaoua, Anne-Sophie Alvarez, Nicolas Pons, Benoît Quinquis, Christian Morabito, Julie-Anne Nazare, Elise Borezée-Durant, Le French Gut Consortium, Florence Haimet, Stanislav Dusko Ehrlich, Karine Valeille, Alexandre Cavezza, Hervé Blottière, Patrick Veiga, Mathieu Almeida, Joël Doré, Robert Benamouzig

JMIR Res Protoc 2025;14:e64894

Comparison of Electronic Surveillance With Routine Monitoring for Patients With Lymphoma at High Risk of Relapse: Prospective Randomized Controlled Phase 3 Trial (Sentinel Lymphoma)

Comparison of Electronic Surveillance With Routine Monitoring for Patients With Lymphoma at High Risk of Relapse: Prospective Randomized Controlled Phase 3 Trial (Sentinel Lymphoma)

A total of 53 patients were included between July 12, 2017, and April 7, 2020, from 14 centers in France: Le Mans (16/52, 31%), Besançon (9/52, 17%), Nantes (6/52, 11%), Bordeaux Bergonié (6/52,11%), Bordeaux Nord (6/52, 11%), Mont de Marson (4/52, 8%), Dijon (1/52, 2%), Grenoble (1/52, 2%), Paris (1/52, 2%), Strasbourg (1/52, 2%), and Vannes (1/52, 2%). One patient withdrew consent before randomization, and 27 patients were randomized to the experimental arm and 25 to the control arm.

Katell Le Dû, Adrien Chauchet, Sophie Sadot-Lebouvier, Olivier Fitoussi, Bijou Fontanet, Arnaud Saint-Lezer, Frédéric Maloisel, Cédric Rossi, Sylvain Carras, Anne Parcelier, Magali Balavoine, Anne-Lise Septans

JMIR Cancer 2025;11:e65960