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Development and Evaluation of Research Methods, Instruments and Tools (1348) Clinical Informatics (2302) Clinical Information and Decision Making (3755) Natural Language Processing (1303) mHealth in a Clinical Setting (1161) Decision Support for Health Professionals (2263) Diagnostic Tools in Mental Health (443) Machine Learning (3225)

Published on in Vol 10 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/98819, first published .
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Conditional Perplexity Scoring for Large Language Model−Generated Differential Diagnoses in Case Reports: Preliminary Computational Evaluation

Conditional Perplexity Scoring for Large Language Model−Generated Differential Diagnoses in Case Reports: Preliminary Computational Evaluation

Authors of this article:

Takanobu Hirosawa1 Author Orcid Image ;   Yukinori Harada1 Author Orcid Image ;   Ren Kawamura1 Author Orcid Image ;   Taro Shimizu1 Author Orcid Image
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Takanobu Hirosawa   1 , MD, PhD ;   Yukinori Harada   1 , MD, PhD ;   Ren Kawamura   1 , MD, PhD ;   Taro Shimizu   1 , MSc, MPH, MBA, MD, PhD

1 Department of Diagnostic and Generalist Medicine, Dokkyo Medical University, Shimotsuga, Tochigi, Japan

Corresponding Author:

  • Takanobu Hirosawa, MD, PhD
  • Department of Diagnostic and Generalist Medicine
  • Dokkyo Medical University
  • 880 Kitakobayashi, Mibu-cho
  • Shimotsuga, Tochigi 321-0293
  • Japan
  • Phone: 81 282-87-2498
  • Email: t.hirosawa1983@gmail.com