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Published on in Vol 10 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/96901, first published .
Doctor examines sick child in hospital bed with worried parents and nurse

Synthetic Content Validation of Pediatric Trust Instruments Using Persona-Driven Large Language Models: Development and Evaluation Study

Synthetic Content Validation of Pediatric Trust Instruments Using Persona-Driven Large Language Models: Development and Evaluation Study

Ella Boone   1 , MSc ;   Katya Loban   1 , LLM, PhD ;   Carmel Daskalo   1 , BSc ;   Suganthi Rajasegaran   1 , PhD ;   Elena Guadagno   2 , MLiS ;   Jeannie Haggerty   3 , PhD ;   Sylvie Lambert   4 , PhD ;   Dan Poenaru   1, 2 , MD, PhD

1 Department of Pediatric Surgery, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada

2 Harvey E. Beardmore Division of Pediatric Surgery, Montreal Children's Hospital, McGill University Health Centre (MUHC), Montreal, QC, Canada

3 Department of Family Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada

4 Ingram School of Nursing, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada

Corresponding Author:

  • Ella Boone, MSc
  • Department of Pediatric Surgery
  • Faculty of Medicine and Health Sciences, McGill University
  • 3D-5252 Blvd de Maisonneuve O
  • Montreal, QC H4A 3S9
  • Canada
  • Phone: 1 2898342690
  • Email: ellaboone02@gmail.com