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Published on in Vol 10 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/86906, first published .
Therapist taking notes on patient records during a session

Measuring Depression Severity With Clinical Global Impression–Severity Scale Scores From Clinical Notes Using Large Language Models: Validation Study

Measuring Depression Severity With Clinical Global Impression–Severity Scale Scores From Clinical Notes Using Large Language Models: Validation Study

Kevin Li   1 , MD ;   Ayah Zirikly   2, 3 , PhD ;   Sarah C Collica   1 , MD ;   Fernando S Goes   1 , MD ;   Congwen Zhao   4 , MS ;   Trang Nguyen   5 , PhD ;   Jane P Gagliardi   6 , MD, MHS ;   Benjamin A Goldstein   4 , PhD ;   Hwanhee Hong   4 , PhD ;   Elizabeth A Stuart   5 , PhD ;   Peter P Zandi   1 , PhD

1 Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, United States

2 Department of Computer Science, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, United States

3 Department of Computer Science, School of Engineering and Applied Science, George Washington University, Washington, DC, United States

4 Department of Biostatistics and Bioinformatics, School of Medicine, Duke University, Durham, NC, United States

5 Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States

6 Department of Psychiatry and Behavioral Sciences, School of Medicine, Duke University, Durham, NC, United States

Corresponding Author:

  • Peter P Zandi, PhD
  • Department of Psychiatry and Behavioral Sciences
  • School of Medicine, Johns Hopkins University
  • 550 N Broadway
  • Baltimore, MD 21205
  • United States
  • Phone: 1 410-614-1923
  • Email: pzandi1@jhu.edu