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Clinical Value of ChatGPT for Epilepsy Presurgical Decision-Making: Systematic Evaluation of Seizure Semiology Interpretation

Clinical Value of ChatGPT for Epilepsy Presurgical Decision-Making: Systematic Evaluation of Seizure Semiology Interpretation

In the publicly sourced cohort, the temporal lobe (T) and frontal lobe (F) accounted for the most significant proportions of EZ-semiology cases, followed by the parietal lobe (P) and occipital lobe (O), with the insular cortex (INS) and cingulate cortex (CING) comprising the most diminutive proportions. The privately sourced cohort exhibited a similar distribution, with a minor variation where the frontal lobe slightly surpassed the temporal lobe in the number of semiology-EZ cases.

Yaxi Luo, Meng Jiao, Neel Fotedar, Jun-En Ding, Ioannis Karakis, Vikram R Rao, Melissa Asmar, Xiaochen Xian, Orwa Aboud, Yuxin Wen, Jack J Lin, Fang-Ming Hung, Hai Sun, Felix Rosenow, Feng Liu

J Med Internet Res 2025;27:e69173

Effects of the National Institutes of Health Stroke Scale and Modified Rankin Scale on Predictive Models of 30-Day Nonelective Readmission and Mortality After Ischemic Stroke: Cohort Study

Effects of the National Institutes of Health Stroke Scale and Modified Rankin Scale on Predictive Models of 30-Day Nonelective Readmission and Mortality After Ischemic Stroke: Cohort Study

For hospitalizations that resulted in readmission within 30 days or death within 30 days post-discharge, the patients tended to be older (median age 78, IQR 68-86 years vs 72, IQR 62-82 years), were less likely to be male (290/688, 42.2% vs 2187/4326, 50.6%; P Table 3 shows results from performance testing of several multivariable predictive models of the composite outcome. The best performing models were TSL (c-statistic=0.685) and TSL plus m RS score at discharge (c-statistic=0.694).

Mai N Nguyen-Huynh, Janet Alexander, Zheng Zhu, Melissa Meighan, Gabriel Escobar

JMIR Med Inform 2025;13:e69102

SEARCH Study: Text Messages and Automated Phone Reminders for HPV Vaccination in Uganda: Randomized Controlled Trial

SEARCH Study: Text Messages and Automated Phone Reminders for HPV Vaccination in Uganda: Randomized Controlled Trial

There was no significant difference in requested mode based on HPV vaccine dose or language (desired text messages for initiation reminders (22/39, 56%), versus for completion reminders (26/39, 67%; P=.35), desired text messages for reminders in English (21/28, 75%) versus in Luganda (27/50, 54%; P=.07). Enrollment flow diagram. Characteristics of study participants. a HPV: human papillomavirus. b KCCA: Kampala Capital City Authority.

Sabrina B Kitaka, Joseph Rujumba, Sarah K Zalwango, Betsy Pfeffer, Lubega Kizza, Juliane P Nattimba, Ashley B Stephens, Nicolette Nabukeera-Barungi, Chelsea S Wynn, Juliet N Babirye, John Mukisa, Ezekiel Mupere, Melissa S Stockwell

JMIR Mhealth Uhealth 2025;13:e63527

Predicting Transvaginal Surgical Mesh Exposure Outcomes Using an Integrated Dataset of Blood Cytokine Levels and Medical Record Data: Machine Learning Approach

Predicting Transvaginal Surgical Mesh Exposure Outcomes Using an Integrated Dataset of Blood Cytokine Levels and Medical Record Data: Machine Learning Approach

Unpaired t tests were conducted on each variable to determine significance (P Demographics of the patients with pelvic organ prolapse (POP) study population (N=20 subjects). Patient blood samples were collected from the same 20 female patients and incubated with sterile polypropylene mesh (2 cm × 2 cm), as detailed in Waugh et al [10]. Plasma layers collected following centrifugation (1500xg, 4 °C) of blood samples were analyzed via multiplex assay to quantify cytokine levels, as in Waugh et al [10].

Mihyun Lim Waugh, Tyler Mills, Nicholas Boltin, Lauren Wolf, Patti Parker, Ronnie Horner, Thomas L Wheeler II, Richard L Goodwin, Melissa A Moss

JMIR Form Res 2025;9:e59631

Improving Diet Quality of People Living With Obesity by Building Effective Dietetic Service Delivery Using Technology in a Primary Health Care Setting: Protocol for a Randomized Controlled Trial

Improving Diet Quality of People Living With Obesity by Building Effective Dietetic Service Delivery Using Technology in a Primary Health Care Setting: Protocol for a Randomized Controlled Trial

P values A sample size of 342 participants (n=171 per group) will have 90% power to detect a difference in change between arms of at least 5% of body weight at 12 months between groups, using a conservative estimate of SD, at 90% power and 5% level of significance. Assuming 20% (n=86) of participants are not followed up, this would necessitate 430 (215 in each group) participants to be recruited.

Deborah A Kerr, Clare E Collins, Andrea Begley, Barbara Mullan, Satvinder S Dhaliwal, Claire E Pulker, Fengqing Zhu, Marie Fialkowski, Richard L Prince, Richard Norman, Anthony P James, Paul Aveyard, Helen Mitchell, Jacquie Garton-Smith, Megan E Rollo, Chloe Maxwell-Smith, Amira Hassan, Hayley Breare, Lucy M Butcher, Christina M Pollard

JMIR Res Protoc 2025;14:e64735