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The Rapid Online Cognitive Assessment for the Detection of Neurocognitive Disorder: Open-Label Study

The Rapid Online Cognitive Assessment for the Detection of Neurocognitive Disorder: Open-Label Study

We first evaluated how Ro CA evaluated patient drawings (Figure 3 A-C). Ro CA classified 97% (44/46) of the cubes correctly, 91% (42/46) of the infinities correctly, and 98% (45/46) of the clocks correctly. We next calculated the accuracy of Ro CA for each drawing individually (Figure 3 D). We compared the accuracy of each drawing to its statistical baseline by bootstrapping, resampling the accuracy, and counting the number of times it fell below the random classifier.

Calvin Howard, Amy Johnson, Joseph Peedicail, Marcus C Ng

J Med Internet Res 2025;27:e66735

Use, Usability, and Experience Testing of a Digital Health Intervention to Support Chronic Kidney Disease Self-Management: Mixed Methods Study

Use, Usability, and Experience Testing of a Digital Health Intervention to Support Chronic Kidney Disease Self-Management: Mixed Methods Study

Self-Management Intervention through Lifestyle Education for Kidney health (SMILE-K) trial intervention group participant characteristics for those assigned to the intervention group and those who activated their My Kidneys & Me (MK&M) account. ae GFR: estimated glomerular filtration rate. b ACR: albumin to creatinine ratio. c Hb A1c: hemoglobin A1c. d CRP: C-reactive protein. e PAM-13: Patient Activation Measure-13.

Courtney J Lightfoot, Thomas J Wilkinson, Roseanne E Billany, Gurneet K Sohansoha, Noemi Vadaszy, Ella C Ford, Melanie J Davies, Thomas Yates, Alice C Smith, Matthew P M Graham-Brown

J Med Internet Res 2025;27:e75845

Improving HIV Prevention Among Heterosexual Men Seeking Sexually Transmitted Infection Services in Malawi: Protocol for a Type I Effectiveness-Implementation Hybrid Randomized Controlled Trial of Systems Navigator–Delivered Integrated Prevention Package (HPTN 112-NJIRA Study)

Improving HIV Prevention Among Heterosexual Men Seeking Sexually Transmitted Infection Services in Malawi: Protocol for a Type I Effectiveness-Implementation Hybrid Randomized Controlled Trial of Systems Navigator–Delivered Integrated Prevention Package (HPTN 112-NJIRA Study)

This would occur in the intervention arm only, but there will not be any syphilis testing done by systems navigators (they only collect urine for N. gonorrhea and C. trachomatis). All participants will complete study staff-administered surveys using validated scales whenever possible, enabling exploration of predictors of Pr EP persistence and informing targeted objectives and strategies to enhance systems navigation and counseling interventions.

Sarah E Rutstein, Laura Limarzi-Klyn, Jane S Chen, Yaw O Agyei, Shahnaz Ahmed, Ian Bell, Myron Cohen, Jessica M Fogel, Vivian Go, Dan Haines, Erica L Hamilton, Irving F Hoffman, Mina C Hosseinipour, Mark A Marzinke, William C Miller, Mathews Mukatipa, Julie Pulerwitz, Hans M L Spiegel, Ting Ye, Mitch Matoga

JMIR Res Protoc 2025;14:e72981