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Intervention for Justice-Involved Homeless Veterans With Co-Occurring Substance Use and Mental Health Disorders: Protocol for a Randomized Controlled Hybrid Effectiveness-Implementation Trial

Intervention for Justice-Involved Homeless Veterans With Co-Occurring Substance Use and Mental Health Disorders: Protocol for a Randomized Controlled Hybrid Effectiveness-Implementation Trial

To account for having veterans at 2 sites, power analyses using G*Power were based on having 4 cells (2 conditions per site) [58]. A sample size of 180 (90 in each condition) will provide 91% power to detect a medium-large effect size at an α of .05 (2-tailed test). On the basis of an N of 180 and of .05, we would have 80% power to detect a Cohen f=0.25, a medium size effect [57]. Thus, after accounting for attenuation and 20% attrition [31,59,60], we will recruit 226 veterans (113 per condition).

Kathryn Bruzios, Paige M Shaffer, Daniel M Blonigen, Michael A Cucciare, Michael Andre, Thomas Byrne, Jennifer Smith, David Smelson

JMIR Res Protoc 2025;14:e70750