Accessibility settings

Published on in Vol 10 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/90968, first published .
3D heart model with medical data, heart scan, and patient information

Supervised Fine-Tuning of Large Language Models With Chain-of-Thought Reasoning for Pediatric Heart Disease Detection in Unstructured Echocardiogram Reports: Algorithm Development and Validation

Supervised Fine-Tuning of Large Language Models With Chain-of-Thought Reasoning for Pediatric Heart Disease Detection in Unstructured Echocardiogram Reports: Algorithm Development and Validation

Haoming Shi   1, 2, 3 , MS ;   Justin B Long   4, 5 , MS, MD ;   Michael C Fiedorek   4, 5 , MD ;   Hannah D Kilday   4, 5 , MD ;   Henry P Foote   6 , MD ;   Christoph P Hornik   6 , MD, MPH, PhD ;   Aditya Nagori   2, 3 , PhD ;   Yifan Xiang   1, 2, 3 , MSE ;   Rishikesan Kamaleswaran   1, 2, 3 , PhD

1 Department of Biomedical Engineering, Duke University, Durham, NC, United States

2 Department of Surgery, Duke University School of Medicine, Durham, NC, United States

3 Department of Anesthesiology, Duke University School of Medicine, Durham, NC, United States

4 Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA, United States

5 Department of Anesthesiology, Children’s Healthcare of Atlanta, Atlanta, GA, United States

6 Department of Pediatrics, Duke University School of Medicine, Durham, NC, United States

Corresponding Author:

  • Haoming Shi, MS
  • Department of Biomedical Engineering
  • Duke University
  • 1427 Fitzpatrick Center Box 90281
  • Durham, NC 27708
  • United States
  • Phone: 1 9196695131
  • Email: haoming.shi@duke.edu