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Published on in Vol 10 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/86899, first published .
Veteran uses laptop for online therapy, showing 'deprexis' program on screen.

Deprexis for Veteran Depression: Open-Label Pilot Trial Examining Feasibility, Acceptability, and Preliminary Efficacy

Deprexis for Veteran Depression: Open-Label Pilot Trial Examining Feasibility, Acceptability, and Preliminary Efficacy

Rahel Pearson   1 , PhD ;   Emma Harris   1 , BA ;   Allison Metts   1 , PhD ;   Christopher Graham Beevers   2 , PhD ;   Paul N Pfeiffer   3 , MD ;   Suzannah Creech   1, 4 , PhD

1 VISN 17 Center of Excellence for Research on Returning War Veterans, Central Texas Veterans Health Care System, Temple, TX, United States

2 Department of Psychology, Institute for Mental Health Research, The University of Texas at Austin, Austin, TX, United States

3 Department of Psychiatry, University of Michigan, Ann Arbor, MI, United States

4 Department of Psychiatry and Behavioral Sciences, Dell Medical School, The University of Texas at Austin, Austin, TX, United States

Corresponding Author:

  • Rahel Pearson, PhD
  • VISN 17 Center of Excellence for Research on Returning War Veterans
  • Central Texas Veterans Health Care System
  • 1901 Veterans Memorial Drive
  • Temple, TX 76504
  • United States
  • Phone: 1 (254) 778-4811
  • Email: rahel.pearson@va.gov