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This paper is in the following e-collection/theme issue:

Formative Evaluation of Digital Health Interventions (5011) Mobile Health (mhealth) (5099) mHealth for Data Collection and Research (1697)

Published on in Vol 10 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/85142, first published .
Man checking sleep score on smartwatch and phone app

Digital Remote Assessment of Motor and Speech Changes in Amyotrophic Lateral Sclerosis: Longitudinal Observational Study

Digital Remote Assessment of Motor and Speech Changes in Amyotrophic Lateral Sclerosis: Longitudinal Observational Study

Authors of this article:

Katherine M Burke1, 2 Author Orcid Image ;   Roland Brown3 Author Orcid Image ;   Narghes Calcagno1, 4 Author Orcid Image ;   Anoopum S Gupta5 Author Orcid Image ;   Krzysztof Z Gajos6 Author Orcid Image ;   Zoe Scheier1 Author Orcid Image ;   Alison Clark1 Author Orcid Image ;   Amrita Iyer1 Author Orcid Image ;   Max P Higgins1 Author Orcid Image ;   Mackenzie Keegan1 Author Orcid Image ;   Timothy B Royse1 Author Orcid Image ;   Evan Remington3 Author Orcid Image ;   Kathryn P Connaghan7 Author Orcid Image ;   Stephen A Johnson8 Author Orcid Image ;   Sheena Chew3 Author Orcid Image ;   M Kelley Erb3 Author Orcid Image ;   James D Berry Author Orcid Image
Article Authors Cited by Tweetations Metrics

Katherine M Burke   1, 2 * , DPT ;   Roland Brown   3 * , PhD ;   Narghes Calcagno   1, 4 , MD ;   Anoopum S Gupta   5 , MD, PhD ;   Krzysztof Z Gajos   6 , PhD ;   Zoe Scheier   1 , DO ;   Alison Clark   1 , MPAS ;   Amrita Iyer   1 , BS ;   Max P Higgins   1 , BS ;   Mackenzie Keegan   1 , BS ;   Timothy B Royse   1 , BS ;   Evan Remington   3 , PhD ;   Kathryn P Connaghan   7 , PhD ;   Stephen A Johnson   8 , MD ;   Sheena Chew   3 , MD ;   M Kelley Erb   3 * , PhD ;   James D Berry   * , MD, MPH

1 Neurological Clinical Research Institute and Sean M. Healey and AMG Center for ALS, Department of Neurology, Massachusetts General Hospital, Boston, MA, United States

2 School of Health and Rehabilitation Sciences, MGH Institute of Health Professions, Boston, MA, United States

3 Biogen, Inc., Cambridge, MA, United States

4 Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy

5 Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States

6 Department of Computer Science, Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, United States

7 Speech and Social Interaction Lab, MGH Institute of Health Professions, Boston, MA, United States

8 Department of Neurology, Mayo Clinic, Scottsdale, AZ, United States

*these authors contributed equally

Corresponding Author:

  • Katherine M Burke, DPT
  • Neurological Clinical Research Institute and Sean M. Healey and AMG Center for ALS, Department of Neurology
  • Massachusetts General Hospital
  • 165 Cambridge Street, 6th Floor
  • Boston, MA 02114
  • United States
  • Phone: 1 6177261844
  • Fax: 1 6177247290
  • Email: katherine.burke@mgh.harvard.edu