Early Detection of Alzheimer's Disease and Related Dementias From Spontaneous Speech Using Foundation Speech and Language Models: Comparative Evaluation

Jingyu Li   ^{1 *} , MS ;   Lingchao Mao   ^{1 *} , PhD ;   Xi Mao   ^{2 *} , PhD ;   Hairong Wang   ³ , PhD ;   Zhendong Wang   ⁴ , PhD ;   Xuelei Sherry Ni   ⁵ , PhD

¹ H. Milton Stewart School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, GA, United States

² Department of Economics, The University of Texas Rio Grande Valley, Edinburg, TX, United States

³ Operations Research and Industrial Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, United States

⁴ Shandong Provincial Key Medical and Health Laboratory of Digital Psychiatry, Shandong Mental Health Center, Jinan, China

⁵ School of Data Science and Analytics, Kennesaw State University, Marietta, GA, United States

*these authors contributed equally