Clinical Decision Support Tool for Early Pancreatic Cancer Detection in Primary Care: Simulation Study

Javiera Martinez-Gutierrez   ^{1, 2, 3 *} , MPH, MD ;   Kaleswari Somasundaram   ^{1 *} , MPhil ;   Christina Maresch Bernardes   ^{4, 5} , PhD ;   Meena Rafiq   ^{1, 2, 6, 7} , MBBS, PhD ;   Silja Schrader   ^{1, 2, 6} , MMS ;   Susan Jordan   ⁴ , PhD ;   Sophie Chima   ^{1, 2} , PhD ;   Lucas De Mendonca   ¹ , MPhil ;   Kit Huckvale   ⁸ , PhD ;   Barbara Hunter   ¹ , PhD ;   Jo-Anne Manski-Nankervis   ^{1, 9, 10} , PhD ;   James Lawson   ¹¹ , BCS ;   Katrina Anderson   ¹¹ , MPH ;   Vivienne Milch   ^{11, 12} , MBBS, MHPol ;   Rachel E Neale   ^{4, 5 *} , PhD ;   Jon Emery   ^{1, 9 *} , MA, MBBCHIR, MRCGP, DPhil

¹ Department of General Practice, Medicine, Dentristry and Health Services, The University of Melbourne, Melbourne, Australia

² Collaborative Centre for Genomic Cancer Medicine, The University of Melbourne, Melbourne, Australia

³ Department of Family Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile

⁴ School of Public Health, The University of Queensland, Brisbane, Australia

⁵ Population Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Australia

⁶ Data Connect, Victorian Comprehensive Cancer Centre, Melbourne, Australia

⁷ Department of Behavioural Science and Health, University College London, London, United Kingdom

⁸ The Digital Health Validitron, Centre for Digital Transformation of Health, The University of Melbourne, Melbourne, Australia

⁹ Department of Primary Care and Family Medicine, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore

¹⁰ National Health Group Polyclinic, National Healthcare Group, Singapore, Singapore

¹¹ Cancer Australia, Sydney, Australia

¹² Caring Futures Institute, Flinders University, Adelaide, Australia

*these authors contributed equally