Published on in Vol 9 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/64973, first published .
The Interactive Care Coordination and Navigation mHealth Intervention for People Experiencing Homelessness: Cost Analysis, Exploratory Financial Cost-Benefit Analysis, and Budget Impact Analysis

The Interactive Care Coordination and Navigation mHealth Intervention for People Experiencing Homelessness: Cost Analysis, Exploratory Financial Cost-Benefit Analysis, and Budget Impact Analysis

The Interactive Care Coordination and Navigation mHealth Intervention for People Experiencing Homelessness: Cost Analysis, Exploratory Financial Cost-Benefit Analysis, and Budget Impact Analysis

1Health Outcomes Division, College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Austin, TX, United States

2Department of Internal Medicine, Dell Medical School, The University of Texas at Austin, Austin, TX, United States

Corresponding Author:

Leticia R Moczygemba, PharmD, PhD


Background: The Interactive Care Coordination and Navigation (iCAN) mobile health intervention aims to improve care coordination and reduce hospital and emergency department visits among people experiencing homelessness.

Objective: This study aimed to conduct a three-part economic evaluation of iCAN, including a (1) cost analysis, (2) exploratory financial cost-benefit analysis, and (3) budget impact analysis (BIA).

Methods: We collected cost and expenditure data from a randomized controlled trial of iCAN to conduct a cost analysis and exploratory financial cost-benefit analysis. Costs were classified as startup and recurring costs for participants and the program. Startup costs included participant supplies for each participant and SMS implementation costs. Recurring costs included the cost of recurring services, SMS text messaging platform maintenance, health information access fees, and personnel salaries. Using the per participant per year (PPPY) costs of iCAN, the minimum savings reduction in the average health care costs among people experiencing homelessness that would lead to a benefit-cost ratio >1 for iCAN was calculated. This savings threshold was calculated by dividing the PPPY cost of iCAN by the average health care costs among people experiencing homelessness multiplied by 100%. The benefit-cost ratio of iCAN was calculated under different savings thresholds from 0% (no savings) to 50%. Costs were calculated PPPY under different scenarios, and the results were used as inputs in a BIA. A probabilistic sensitivity analysis was conducted to incorporate uncertainty around cost estimates. Costs are in 2022 US $.

Results: The total cost of iCAN was US $2865 PPPY, which was made up of US $265 in startup (9%) and US $2600 (91%) in recurring costs PPPY. The minimum savings threshold that would cause iCAN to have a positive return on investment is 7.8%. This means that if average health care costs (US $36,917) among people experiencing homelessness were reduced by more than 7.8% through iCAN, the financial benefits would outweigh the costs of the intervention. When health care costs are reduced by 25% ($9229/$36,917; equal to 56% [$9229/$16,609] of the average cost of an inpatient visit), the benefit-cost ratio is 3.22, which means that iCAN produces US $2.22 in health care savings per US $1 spent. The BIA estimated that implementing iCAN for 10,250 people experiencing homelessness over 5 years would have a financial cost of US $28.7 million, which could be reduced to US $2.2 million if at least 8% ($2880/$36,917) of average health care costs among people experiencing homelessness are reduced through the intervention.

Conclusions: If average costs of emergency department and hospital visits among people experiencing homelessness were reduced by more than 7.8% ($2880/$36,917) through iCAN, the financial benefits would outweigh the costs of the intervention. As the savings threshold increases, it results in a higher benefit-cost ratio.

Trial Registration: ClinicalTrials NCT05365867; https://clinicaltrials.gov/study/NCT05365867

JMIR Form Res 2025;9:e64973

doi:10.2196/64973

Keywords



People experiencing homelessness have higher rates of emergency department (ED) and hospital visits than housed groups. A systematic review reported that, on average, across 10 studies, the number of ED visits among people experiencing homelessness ranged from 0.7 to 5.8 visits annually. Furthermore, 5 of these studies compared ED use between people experiencing homelessness and housed groups and found that the rates were higher in people experiencing homelessness [Vohra N, Paudyal V, Price MJ. Homelessness and the use of emergency department as a source of healthcare: a systematic review. Int J Emerg Med. Jul 28, 2022;15(1):32. [CrossRef] [Medline]1]. It has also been reported that people experiencing homelessness have 1.9 times the odds of hospital readmissions compared with housed groups [Miyawaki A, Hasegawa K, Figueroa JF, Tsugawa Y. Hospital readmission and emergency department revisits of homeless patients treated at homeless-serving hospitals in the USA: observational study. J Gen Intern Med. Sep 2020;35(9):2560-2568. [CrossRef] [Medline]2]. Furthermore, a study of the hospital use patterns of people experiencing homelessness using electronic health data in an integrated health system in the United States found that people experiencing homelessness have higher rates of 30-day readmissions and longer lengths of stay in the hospital compared with those that are not homeless [Banerjee S, Yassin M, Dyer WT, Thomas TW, Rodriguez LA, Schmittdiel J. Hospital readmissions among patients experiencing homelessness: an electronic health record data study. Perm J. Mar 15, 2024;28(1):55-61. [CrossRef] [Medline]3]. Some of the reasons for high ED and hospital utilization in people experiencing homelessness includes inadequate access to primary care and challenges taking medications due to medications being lost or stolen and competing priorities for basic needs such as shelter and food [Liu M, Hwang SW. Health care for homeless people. Nat Rev Dis Primers. 2021;7(1):5. [CrossRef] [Medline]4,Thurman W, Moczygemba LR, Baffoe JO. “Without my medication, I’m a wreck”: photo-elicitation to explore medication use among people experiencing homelessness. Res Social Adm Pharm. Jul 2022;18(7):3149-3157. [CrossRef] [Medline]5].

Mobile health (mHealth) is a type of digital technology that involves the use of mobile devices such as mobile phones to deliver health services [What is digital health? US Food and Drug Administration. URL: https://www.fda.gov/medical-devices/digital-health-center-excellence/what-digital-health [Accessed 2025-01-13] 6]. The ubiquity and declining costs of mobile phones in the United States and other countries has generated interest in the use of mHealth to improve population and public health [Velmovitsky PE, Kirolos M, Alencar P, Leatherdale S, Cowan D, Morita PP. Leveraging mHealth technologies for public health. JMIR Public Health Surveill. Sep 12, 2024;10:e49719. [CrossRef] [Medline]7,mHealth: use of appropriate digital technologies for public health: report by the director-general. World Health Organization; 2017. URL: https://iris.who.int/bitstream/handle/10665/274134/B142_20-en.pdf?sequence=1&isAllowed=y [Accessed 2025-03-06] 8]. Studies have shown that mHealth can be effective in improving outcomes such as increasing patient adherence and healthy behaviors in chronic disease management [Kyaw TL, Ng N, Theocharaki M, Wennberg P, Sahlen KG. Cost-effectiveness of digital tools for behavior change interventions among people with chronic diseases: systematic review. Interact J Med Res. Feb 16, 2023;12:e42396. [CrossRef] [Medline]9], and reducing ED use [Arora S, Peters AL, Burner E, Lam CN, Menchine M. Trial to examine text message-based mHealth in emergency department patients with diabetes (TExT-MED): a randomized controlled trial. Ann Emerg Med. 2014;63(6):745-754. [CrossRef] [Medline]10-Ladley A, Hieger AW, Arthur J, Broom M. Educational text messages decreased emergency department utilization among infant caregivers: a randomized trial. Acad Pediatr. Aug 2018;18(6):636-641. [CrossRef] [Medline]12]. According to 2 systematic reviews of cost effectiveness of digital interventions (eg, telephone, SMS text messaging, and mHealth apps), for those studies that included some type of economic evaluation, there is some evidence that these interventions may be cost-beneficial [Kyaw TL, Ng N, Theocharaki M, Wennberg P, Sahlen KG. Cost-effectiveness of digital tools for behavior change interventions among people with chronic diseases: systematic review. Interact J Med Res. Feb 16, 2023;12:e42396. [CrossRef] [Medline]9,Gentili A, Failla G, Melnyk A, et al. The cost-effectiveness of digital health interventions: a systematic review of the literature. Front Public Health. 2022;10:787135. [CrossRef] [Medline]13]. Even in the mHealth interventions where the outcomes were not statistically significant or cost-savings were not addressed, a reduction in preventable and nonemergent ED visits suggest likely significant cost-savings for health care payers in the community [Gentili A, Failla G, Melnyk A, et al. The cost-effectiveness of digital health interventions: a systematic review of the literature. Front Public Health. 2022;10:787135. [CrossRef] [Medline]13].

Given that mobile phones can reach traditionally hard to reach groups, including people experiencing homelessness [Moczygemba LR, Cox LS, Marks SA, Robinson MA, Goode JVR, Jafari N. Homeless patients’ perceptions about using cell phones to manage medications and attend appointments. Int J Pharm Pract. Jun 2017;25(3):220-230. [CrossRef] [Medline]14], mHealth interventions should be considered when designing interventions to decrease ED and hospital visits in people experiencing homelessness. In a small pre-post study, people experiencing homelessness indicated that it was easy to use a mobile phone to participate in an mHealth intervention, and a qualitative study of people experiencing homelessness in the pre-post study found that mobile phones empowered people experiencing homelessness to self-manage their health and social needs [Moczygemba LR, Thurman W, Tormey K, Hudzik A, Welton-Arndt L, Kim E. GPS mobile health intervention among people experiencing homelessness: pre-post study. JMIR Mhealth Uhealth. Nov 3, 2021;9(11):e25553. [CrossRef] [Medline]15,Thurman W, Semwal M, Moczygemba LR, Hilbelink M. Smartphone technology to empower people experiencing homelessness: secondary analysis. J Med Internet Res. Sep 29, 2021;23(9):e27787. [CrossRef] [Medline]16]. A scoping review of 12 studies found that using technology on mobile phones such as SMS text messaging and apps could help improve access to mental health services for youth experiencing homelessness, with evidence of feasibility and acceptability by users [Lal S, Elias S, Sieu V, Peredo R. The use of technology to provide mental health services to youth experiencing homelessness: scoping review. J Med Internet Res. Jan 16, 2023;25:e41939. [CrossRef] [Medline]17]. The scalability of mHealth interventions for people experiencing homelessness will depend, in part, on whether its benefits outweigh the costs of the intervention. Thus, in this study, we will estimate the costs of an mHealth intervention, which will be described in the Methods section, that was implemented to decrease ED and hospital use among people experiencing homelessness and conduct an exploratory financial cost-benefit analysis and preliminary budget impact analysis to evaluate the potential cost-savings from this intervention for people experiencing homelessness.


Overview

Interactive Care Coordination and Navigation (iCAN) is a community-based mHealth intervention in the United States that was designed using findings from previous studies related to acceptability and benefits of mHealth interventions in people experiencing homelessness [Moczygemba LR, Thurman W, Tormey K, Hudzik A, Welton-Arndt L, Kim E. GPS mobile health intervention among people experiencing homelessness: pre-post study. JMIR Mhealth Uhealth. Nov 3, 2021;9(11):e25553. [CrossRef] [Medline]15,Thurman W, Semwal M, Moczygemba LR, Hilbelink M. Smartphone technology to empower people experiencing homelessness: secondary analysis. J Med Internet Res. Sep 29, 2021;23(9):e27787. [CrossRef] [Medline]16] and with feedback from homeless care providers and people with the lived experience of homelessness. The purpose of iCAN, which is implemented at community-based sites that provide homeless services, is to improve care coordination between health and social services for people experiencing homelessness with a goal of reducing hospitalizations and ED visits. It is a multicomponent intervention comprised of SMS text messages, preinstalled apps and resources, including a bus pass, and a case manager who conducted telephone encounters and used bidirectional SMS texting to communicate with participants. Participants received 3‐5 messages daily regarding medication adherence and appointment reminders, general health messages, motivational messages such as encouragement to keep goals, and as needed messages for local information (eg, weather updates and resource fair information). Participants were also able to text the case manager or study staff. Within 72 hours of enrollment, the case manager conducted a telephone assessment to identify relevant health and social needs whereby they could connect participants to medical and social services in the community. Case managers received weekly reports twice about ED and hospital use from the local health information exchange (HIE) and contacted participants within 72 hours of an ED or hospital visit to help coordinate care needs for managing discharge instructions. People experiencing homelessness who were 18 years or older, owned a cell phone with service, had at least 2 chronic health conditions, had at least 2 hospitalizations or ED visits 6 months before enrollment, scored 4 or higher on the Rapid Estimate of Adult Literacy in Medicine-Short Form, and scored greater than 17 on the Mini-Mental State Exam were eligible to participate in iCAN. There was a total of 60 participants in the iCAN intervention. The mean age of participants in the iCAN intervention was 50.1 (SD 10.2) years. Most (42/60, 70%) were men; over half (34/60, 57%) reported their race as White and 32% (19/60) reported their race as Black. The randomized controlled trial (RCT) of iCAN completed recruitment in August 2023 and data analysis is ongoing.

Informed by previous studies of mHealth interventions [Prinja S, Gupta A, Bahuguna P, Nimesh R. Cost analysis of implementing mHealth intervention for maternal, newborn & child health care through community health workers: assessment of ReMIND program in Uttar Pradesh, India. BMC Pregnancy Childbirth. 2018;18(1):390. [CrossRef] [Medline]18-Avanceña ALV, Brody C, Chhoun P, Tuot S, Yi S. Connecting female entertainment workers in Cambodia to health care services using mHealth: economic evaluation of mobile link. JMIR Form Res. Jul 25, 2024;8:e52734. [CrossRef] [Medline]21], we conducted a three-part economic evaluation of iCAN, including a (1) cost analysis, (2) exploratory financial cost-benefit analysis, and (3) budget impact analysis. For the cost analysis, we used expenditure data from the iCAN RCT to determine the total cost and cost per participant per year (PPPY). Using these costs, we conducted an exploratory cost-benefit analysis to understand the minimum health care savings that would cause iCAN to have a positive return on investment. Finally, we conducted a budget impact analysis to determine the financial requirements of scaling up the iCAN intervention in a metropolitan area. For the cost and cost-benefit analyses, we used scenario and probabilistic sensitivity analyses to determine the effect of different assumptions and uncertainty in existing data on our findings.

We followed the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) [Husereau D, Drummond M, Augustovski F, et al. Consolidated Health Economic Evaluation Reporting Standards 2022 (CHEERS 2022) statement: updated reporting guidance for health economic evaluations. BMJ. 2022;376:e067975. [CrossRef] [Medline]22], the International Training and Education Center for Health (I-TECH) Applied Economic Evaluation of Digital Health Interventions Report [Babigumira JB, Dolan S, Shade S, et al. Applied economic evaluation of digital health interventions. I-TECH. URL: https://www.go2itech.org/wp-content/uploads/2021/02/I-TECH_HIS_Economic_Evaluation.pdf [Accessed 2024-07-30] 23], the The International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Budget Impact Analysis Report [Sullivan SD, Mauskopf JA, Augustovski F, et al. Budget impact analysis-principles of good practice: report of the ISPOR 2012 Budget Impact Analysis Good Practice II Task Force. Value Health. 2014;17(1):5-14. [CrossRef] [Medline]24], and other guidance [Rascati K. Essentials of Pharmacoeconomics. Lippincott Williams & Wilkins; 2020. 25] in conducting this study. We used a public-payer perspective, assuming that the majority of people experiencing homelessness do not have private health insurance and cannot pay for out-of-pocket health care costs [Baggett TP, O’Connell JJ, Singer DE, Rigotti NA. The unmet health care needs of homeless adults: a national study. Am J Public Health. 2010;100(7):1326-1333. [CrossRef] [Medline]26,Fryling LR, Mazanec P, Rodriguez RM. Barriers to homeless persons acquiring health insurance through the Affordable Care Act. J Emerg Med. Nov 2015;49(5):755-762. [CrossRef] [Medline]27]. Thus, the costs of iCAN and health care services used by people experiencing homelessness are borne by the public sector through public health care payers (eg, Medicaid), health care systems, and local governments.

Data Collection

Intervention Costs

We collected expenditure records from the ongoing iCAN RCT to determine intervention costs. Intervention costs were separated into startup and recurring costs using a microcosting approach [Špacírová Z, Epstein D, García-Mochón L, Rovira J, Olry de Labry Lima A, Espín J. A general framework for classifying costing methods for economic evaluation of health care. Eur J Health Econ. 2020;21(4):529-542. [CrossRef] [Medline]28].

Startup or capital costs were separated into participant-related and program-related costs. Participant-related startup costs included a cell phone, phone case, armband, charging cable and block, rechargeable power bank, and drawstring backpack. Program-related startup costs included the initial payment for the SMS text messaging platform and printing costs for training materials.

Recurring costs were separated into participant-related, program-related, and personnel costs. Participant-related recurring costs included a monthly bus pass and a SIM card with a phone plan, which are given to each participant. Program-related recurring costs included monthly SMS text messaging platform maintenance fees and HIE data access fees. Access to HIE data are required to monitor ED and inpatient health care use of participants during the trial, however, this expense may be excluded during the scaling up of iCAN in the community. We explored this scenario in sensitivity analysis.

Personnel-related recurring costs included the salaries of a case manager and program coordinator. The case manager spent approximately 20 hours per week communicating with 24 enrolled participants; for 60 participants, this was equivalent to 1.25 case managers. The program coordinator, a role assumed by graduate research assistants during the iCAN trial, is responsible for several operational and administrative tasks, including setting up participants’ cell phones (1 h per phone), training participants on the intervention (1 h per participant), and troubleshooting any technology-related issues (2 h per week). The case manager’s annual salary was estimated based on the average hourly wage of social workers in Texas from the Bureau of Labor Statistics multiplied by the total work hours (2500) per year [US Bureau of Labor Statistics. URL: https://data.bls.gov/timeseries/CUUR0000SAM?output_view=pct_12mths [Accessed 2022-12-14] 29]. The salary of the program coordinator was based on the average hourly pay of graduate research assistants, which is available on the human resources website of The University of Texas at Austin [Student employee compensation. The University of Texas at Austin Human Resources. URL: https://hr.utexas.edu/student/student-employee-compensation [Accessed 2024-07-27] 30]. The hours spent by the program coordinator on specific tasks were determined through interviews with trial staff and a review of staff records, and the total time spent was used to calculate the program coordinator’s annual salary.

Health Care Costs

We used existing data to estimate the annual health care costs related to inpatient and ED care among people experiencing homelessness. We relied on previous studies on health care utilization among people experiencing homelessness in Texas to determine the average number and range of ED [Petrovich JC, Hunt JJ, North CS, Pollio DE, Roark Murphy E. Comparing unsheltered and sheltered homeless: demographics, health services use and predictors of health services use. Community Ment Health J. Feb 2020;56(2):271-279. [CrossRef] [Medline]31-Holmes CT, Holmes KA, MacDonald A, et al. Dedicated homeless clinics reduce inappropriate emergency department utilization. J Am Coll Emerg Physicians Open. 2020;1(5):829-836. [CrossRef] [Medline]34] and inpatient visits [Petrovich JC, Hunt JJ, North CS, Pollio DE, Roark Murphy E. Comparing unsheltered and sheltered homeless: demographics, health services use and predictors of health services use. Community Ment Health J. Feb 2020;56(2):271-279. [CrossRef] [Medline]31,Buck DS, Brown CA, Mortensen K, Riggs JW, Franzini L. Comparing homeless and domiciled patients’ utilization of the Harris County, Texas public hospital system. J Health Care Poor Underserved. 2012;23(4):1660-1670. [CrossRef] [Medline]35] (

Multimedia Appendix 1

Annual emergency department and inpatient health care utilization among people experiencing homelessness.

DOCX File, 16 KBMultimedia Appendix 1). We took the weighted average and median of ED and inpatient visits across studies, which resulted in equivalent values and were comparable with the estimates from other jurisdictions and the United States [Coe AB, Moczygemba LR, Harpe SE, Gatewood SBS. Homeless patients’ use of urban emergency departments in the United States. J Ambul Care Manage. 2015;38(1):48-58. [CrossRef] [Medline]36-Lin WC, Bharel M, Zhang J, O’Connell E, Clark RE. Frequent emergency department visits and hospitalizations among homeless people with Medicaid: implications for Medicaid expansion. Am J Public Health. Nov 2015;105 Suppl 5(Suppl 5):S716-S722. [CrossRef] [Medline]40]. We then multiplied these figures by the average cost of each service from the 2022 Medical Expenditure Panel Survey-Household Component (MEPS-HC) database [MEPS-HC data tools. AHRQ. URL: https://datatools.ahrq.gov/meps-hc [Accessed 2024-11-08] 41]. With the average cost of inpatient (US $16,609, [SE $860]) and ED visits (US $1233 [SE $66]) from MEPS-HC, we used a total health care cost of US $36,916 PPPY. This average cost is comparable with what previous health care utilization studies among people experiencing homelessness who use health care services have reported in Texas and other locations [Petrovich JC, Hunt JJ, North CS, Pollio DE, Roark Murphy E. Comparing unsheltered and sheltered homeless: demographics, health services use and predictors of health services use. Community Ment Health J. Feb 2020;56(2):271-279. [CrossRef] [Medline]31-Lin WC, Bharel M, Zhang J, O’Connell E, Clark RE. Frequent emergency department visits and hospitalizations among homeless people with Medicaid: implications for Medicaid expansion. Am J Public Health. Nov 2015;105 Suppl 5(Suppl 5):S716-S722. [CrossRef] [Medline]40].

Analysis

Cost Analysis

We calculated the total costs of iCAN by adding up all the startup and recurring intervention costs. We also calculated the PPPY costs by dividing the total costs by 60, which is the number of enrolled participants in the iCAN RCT. In scenario analyses, we varied assumptions around the cost inputs (

Multimedia Appendix 2

Scenarios explored in the cost analysis of Interactive Care Coordination and Navigation, an mHealthmobile health intervention for people experiencing homelessness in the United States.

DOCX File, 15 KBMultimedia Appendix 2) and calculated total and PPPY costs under each scenario.

Cost-Benefit Analysis

Using the PPPY costs of iCAN, we calculated the minimum savings or reduction in the average health care costs among people experiencing homelessness that would lead to a benefit-cost ratio >1 for iCAN, where the financial benefits associated with the intervention outweigh its costs. We calculated this “savings threshold” by dividing the PPPY cost of iCAN by the average health care costs among people experiencing homelessness multiplied by 100%. For example, if the PPPY cost of iCAN is 10% of the average health care costs among people experiencing homelessness, a health care cost reduction of >10% (the savings threshold) would lead to a benefit-cost ratio >1 for iCAN. These savings can be accrued by reducing the number or severity of ED and inpatient visits. We then calculated the benefit-cost ratio of iCAN under different savings thresholds from 0% (no savings) to 50%.

To account for uncertainty in various cost inputs (ie, cost of the iCAN, number of ED, and inpatient visits), we conducted a probabilistic sensitivity analysis. A common approach in economic modeling, probabilistic sensitivity analysis involves generating probability distributions for each input using the best available parameter values and then drawing 10,000 random values of each input to produce a distribution of results. From these 10,000 estimates, we determined the mean, median, and 95% probable interval of the savings threshold for iCAN. We assigned gamma distributions for iCAN and health care costs and Poisson distributions for the annual number of inpatient and ED visits among people experiencing homelessness.

Budget Impact Analysis

We conducted a budget impact analysis to determine the financial requirements of implementing iCAN for people experiencing homelessness in a metropolitan area. We used a 5-year time horizon and selected Travis County, Texas, which includes the city of Austin where the iCAN trial was conducted, as the setting of the analysis. The number of unsheltered people experiencing homelessness in the first year was assumed to be 3990 based on estimates of the Homelessness Response System [Austin count of homeless people returns this weekend. Here’s what we know. Austin American-Statesman. URL: https:/​/www.​statesman.com/​story/​news/​2023/​01/​27/​austin-texas-annual-count-homeless-people-ending-community-homlessness-coalition/​69839931007/​ [Accessed 2024-03-07] 42]. We assumed that the people experiencing homelessness population would grow annually by 3.4%, which is the estimated population growth rate for people experiencing homelessness by the US Department of Housing and Urban Development in 2023 [Department of Housing and Urban Development (HUD). URL: https://www.hud.gov/ [Accessed 2024-03-07] 43]. We further assumed that only 60% of people experiencing homelessness would be eligible to participate in iCAN based on previous use of ED and inpatient services based on trial data and previously published studies. Finally, we assumed that only 80% of eligible people experiencing homelessness would participate in iCAN based on engagement data from the trial.

We included fixed and variable startup costs and variable recurring costs in the budget impact analysis. Fixed start-up costs, which were only paid in the first year of program implementation regardless of the number of participants, included the costs of the SMS text messaging platform and iCAN training materials. Variable startup costs included the 1-time cost of supplies (eg, cell phone) per participant. Recurring costs were the cost of services and salaries that varied based on the number of participants; these costs included SMS text messaging platform maintenance fees, HIE data access, personnel salaries, and annual bus passes and phone plans for each participant. We used a medical inflation rate of 2.3% in estimating future costs.

Ethical Considerations

The trial described in the study was approved by the University of Texas Institutional Board (STUDY00002666). The consent form indicated that research data would be kept for use in secondary analyses.


Cost Analysis

The total cost of implementing iCAN to 60 participants for 1 year was US $170,921. The startup costs of iCAN (US $15,925) were estimated to be 9.3% ($15,925/$171,921) of the total cost (Table 1) and the remainder ($155,996/$171,921, 90.7%) were attributable to recurring costs (US $155,996), particularly personnel costs (US $84,908; Table 2). The startup and recurring costs PPPY were US $265 and US $2600, respectively, leading to a total PPPY cost of US $2865 PPPY (Table 3).

Table 1. Startup costs of Interactive Care Coordination and Navigation, a mobile health intervention for people experiencing homelessness in the United States, for a cost analysis. Total costs are calculated based on 60 participants. Costs are in 2022 US $.
ItemUnit cost per participant (US $)Total cost (US $)
Participant-related
Cell phone149.998999.40
Phone case12.99779.40
Arm band8.99539.40
Charging block3.50210.00
USB-C charging cable3.50210.00
Power bank14.99899.40
Drawstring backpack1.3480.40
Subtotal195.3011,718.00
Program-related
Text messaging platform implementation59.803588.00
Printing costs for training binder supplies10.31618.59
Subtotal70.114206.59
Total265.4115,924.59
Table 2. Recurring costs of Interactive Care Coordination and Navigation, an mobile health intervention for people experiencing homelessness in the United States, for a cost analysis. Total costs were calculated for 60 participants. Costs are in 2022 US $.
ItemUnit cost (US $)UnitsTotal annual cost (US $)
Participant-related
Bus pass41.25 per month12 months per participant29,700
Sim card or phone plan210 per 6 months12 months per participant25,200
Subtotala54,900
Program-related
SMS text messaging platform maintenance99 per month12 months for all participants1188
HIEb data access200 per hour750 hours for all participants15,000
Subtotal16,188
Personnel-related
Program coordinatorc17 per hour224 hours for all participants3808
Case worker32.44 per hour2500 hours for all participants81,100
Subtotal84,908
Total155,996

aNot applicable.

bHIE: health information exchange.

cIncludes time spent on setting up (1 h/participant) and training (1 h/participant) participants and maintenance (2 h/wk).

Table 3. Per participant per year costs of Interactive Care Coordination and Navigation, a mobile health intervention for people experiencing homelessness in the United States, for a cost analysis. Costs are in 2022 US $.
CategoryCost PPPYa (US $)
Startup cost
Participant-related195.30
Program-related70.11
Subtotal265.41
Recurring cost
Participant-related915.00
Program-related269.80
Personnel-related1415.13
Subtotal2599.93
Total cost2865.34

aPPPY: per participant per year.

The total PPPY cost of iCAN intervention varied slightly under different scenarios (Table 4). For example, when startup costs were excluded (Scenario A), recurring costs PPPY was US $2600. Excluding the cost of HIE data access (Scenario C) led to a similar PPPY cost of US $2615. The removal of bus passes and HIE data access (Scenario D) produced the lowest cost of US $2120 PPPY.

Table 4. Results of scenario analyses for a cost analysis of Interactive Care Coordination and Navigation, an mobile health intervention for people experiencing homelessness in the United States. All costs are in PPPYa 2022 US $.
Type of costBase caseScenario AScenario BScenario CScenario D
Startup costs (US $)2650265265265
Recurring costs (US $)26002600210523501855
Total iCANb costs (US $)28652600237026152120
Savings threshold7.87.06.47.15.7

aPPPY: per participant per year.

biCAN: Interactive Care Coordination and Navigation.

In Table 4, the savings threshold refers to the percent (%) reduction in average health care costs for ED and inpatient care among people experiencing homelessness. The base case includes both startup and recurring costs. Scenario A includes recurring costs only. Scenario B includes startup costs and recurring costs without the bus pass. Scenario C include startup costs and recurring costs without HIE data access. Scenario D includes startup costs and recurring costs without the bus pass and HIE data access.

Cost-Benefit Analysis

When the cost of iCAN PPPY equals the base-case estimate (US $2865), the savings threshold is 7.8% (Table 2). This means that if average health care costs (US $36,917) among people experiencing homelessness were reduced by more than 7.8% through iCAN, the financial benefits would outweigh the costs of the intervention. A higher savings threshold is associated with a higher benefit-cost ratio for iCAN (Figure 1). When 10% ($3692/$N36,917) of average health care costs among people experiencing homelessness are averted (equal to the average cost of 3 ED visits), iCAN has a benefit-cost ratio of 1.29. When health care costs are reduced by 25% ($9229/N$36,917; equal to 56% [$9229/N$16,609] of the average cost of an inpatient visit), the benefit-cost ratio is 3.22, which means that iCAN produces US $2.22 in health care savings per US $1 spent.

Figure 1. Benefit-cost ratio of Interactive Care Coordination and Navigation, an mobile health intervention for people experiencing homelessness in the United States, under varying savings thresholds.

Figure 1 shows the benefit-cost ratio of iCAN under different savings thresholds, which is the percent (%) reduction in average health care costs for ED and inpatient care among people experiencing homelessness. Average health care costs were calculated using the weighted average of ED and inpatient visits among people experiencing homelessness from previous studies, whose value was equivalent to the median. The dotted red line marks a benefit-cost ratio of 1, which occurs when the benefits or financial savings of iCAN outweigh its costs. The probabilistic sensitivity analyses, which account for uncertainty in the costs of iCAN and the average health care costs of people experiencing homelessness, found a median savings threshold of 8.2% (95% probable interval 3.2‐94.0). The average savings threshold was higher at 21%.

Budget Impact Analysis

The 5-year financial cost of implementing the iCAN intervention in Travis County for 10,250 people experiencing homelessness was around US $28.7 million (Table 5). If at least 5% of average health care costs among people experiencing homelessness are averted, the net budget impact is US $9.7 million. If average health care savings increased to 7%, the net budget impact of iCAN is further reduced to US $2.2 million.

Table 5. A 5-year budget impact analysis of Interactive Care Coordination and Navigation, an mobile health intervention for people experiencing homelessness in the United States (the 5-year total costs were calculated for the total number of people experiencing homelessness participating in Interactive Care Coordination and Navigation and health care savings were calculated based on the average health care costs for emergency department and inpatient care among people experiencing homelessness per year [US $36,917] among those who use these services).
Year 1Year 2Year 3Year 4Year 55-year total
Total number of participants, n1915198020482117218910,250
Intervention costs (US $)
Fixed costs420700004207
Startup costs, PPPYa1951951951951952,001,764
Recurring costs, PPPY2600260026002600260026,648,502
Total financial cost (US $)5,357,6375,535,4485,723,6535,918,2576,119,47828,654,472
Net budget impact (US $)
5% health care savings1,822,4661,880,0801,944,0022,010,0992,078,4429,735,088
7% health care savings408,397417,933432,142446,835462,0282,167,335

aPPPY: per participant per year.


Principal Results

In this study, we found, using a base-case estimate of US $2865, that a reduction in ED and hospital costs (estimated to be US $36,916 PPPY) of about 8%, which equals the cost of 2 ED visits PPPY, through iCAN would outweigh the costs of the intervention. Higher reductions in ED and hospital costs would result in a higher benefit-cost ratio for iCAN. While the economic value of mHealth interventions have been previously explored, none have focused on interventions for people experiencing homelessness. In total, 29 out of 39 studies evaluated in a systematic review conducted by Iribarren et al [Iribarren SJ, Cato K, Falzon L, Stone PW. What is the economic evidence for mHealth? A systematic review of economic evaluations of mHealth solutions. Plos one. 2017;12(2):e0170581. [CrossRef] [Medline]44] in 2017 concluded that mHealth interventions show cost-effectiveness, economic benefit, or cost savings. Just over half of the mHealth interventions included SMS text messaging as the mHealth-related function in the intervention, with 77% (17/22) of these interventions reporting positive cost outcomes [Iribarren SJ, Cato K, Falzon L, Stone PW. What is the economic evidence for mHealth? A systematic review of economic evaluations of mHealth solutions. Plos one. 2017;12(2):e0170581. [CrossRef] [Medline]44]. However, many limitations were identified in this systematic review. Of the 39 studies included in the review, only 12 were considered high-quality economic evaluations, which was defined as meeting at least 90% (21/24) of the items in the CHEERS checklist. In 2022, Gentili et al [Gentili A, Failla G, Melnyk A, et al. The cost-effectiveness of digital health interventions: a systematic review of the literature. Front Public Health. 2022;10:787135. [CrossRef] [Medline]13] conducted a systematic review of digital health interventions, which includes mHealth and other technologies such as telehealth, evaluating studies published after the time period evaluated by Iribarren et al [Iribarren SJ, Cato K, Falzon L, Stone PW. What is the economic evidence for mHealth? A systematic review of economic evaluations of mHealth solutions. Plos one. 2017;12(2):e0170581. [CrossRef] [Medline]44]. Furthermore, 35 studies were included, and the findings were relatively consistent with that of Iribarren et al [Iribarren SJ, Cato K, Falzon L, Stone PW. What is the economic evidence for mHealth? A systematic review of economic evaluations of mHealth solutions. Plos one. 2017;12(2):e0170581. [CrossRef] [Medline]44]. Only 12 of the 35 studies met at least 90% (21/24) of the items on the CHEERS checklist [Gentili A, Failla G, Melnyk A, et al. The cost-effectiveness of digital health interventions: a systematic review of the literature. Front Public Health. 2022;10:787135. [CrossRef] [Medline]13]. While the quality of economic evaluation was the focus of these systematic reviews, there is little evaluation of the budgetary impact and scalability of the included studies. Budget impact analyses were not conducted for these studies, and any evaluations on the economic scalability and sustainability of the interventions were preliminary, suggesting the need for formal budget impact analyses on mHealth interventions.

Another mHealth intervention used SMS to increase participation in their own care and decrease the number of no-show appointments in homeless veterans at a metropolitan Veterans Health Administration hospital. There was a significant decrease in the number of appointments cancelled by the patient and no-show appointments, and there was a significant reduction in ED visits. This study also showed that there were significant cost-savings when comparing the costs of implementing and maintaining SMS appointment reminders with the cost of unutilized services due to cancelled and no-show appointments [McInnes DK, Petrakis BA, Gifford AL, et al. Retaining homeless veterans in outpatient care: a pilot study of mobile phone text message appointment reminders. Am J Public Health. 2014;104(Suppl 4):S588-S594. [CrossRef] [Medline]45]. A systematic review conducted in 2014 found that studies that evaluated cost-effectiveness showed cost savings associated with SMS services compared with standard of care while maintaining equal efficacy of interventions [Beratarrechea A, Lee AG, Willner JM, Jahangir E, Ciapponi A, Rubinstein A. The impact of mobile health interventions on chronic disease outcomes in developing countries: a systematic review. Telemed J E Health. 2014;20(1):75-82. [CrossRef] [Medline]46]. Even in the mHealth interventions where the outcomes were not statistically significant or cost-savings were not addressed, a reduction in preventable and nonemergent ED visits suggest likely significant cost-savings for health care payers in the community [Gentili A, Failla G, Melnyk A, et al. The cost-effectiveness of digital health interventions: a systematic review of the literature. Front Public Health. 2022;10:787135. [CrossRef] [Medline]13,Iribarren SJ, Cato K, Falzon L, Stone PW. What is the economic evidence for mHealth? A systematic review of economic evaluations of mHealth solutions. Plos one. 2017;12(2):e0170581. [CrossRef] [Medline]44,Katz R, Mesfin T, Barr K. Lessons from a community-based mHealth diabetes self-management program: it’s not just about the cell phone. J Health Commun. 2012;17(Suppl 1):67-72. [CrossRef] [Medline]47].

Our study adds to this literature by estimating the minimum health care savings needed for an mHealth intervention like iCAN to have positive net financial benefits. However, our analysis excludes other benefits that may be associated with iCAN, such as improvements in health outcomes and health-related quality of life. These health-related benefits should be quantified, valued, and added to the cost-benefit analysis or cost-effectiveness analysis to gain a more comprehensive picture of iCAN’s overall value.

Research has shown that people experiencing homelessness use more health care services than individuals with stable housing. In our analysis, we relied on previously published estimates of ED and inpatient health care use among people experiencing homelessness in Texas, which all found that use of these services is common (>1) among people experiencing homelessness who have a history of using these services. For example, single-center retrospective studies in Harris County, Texas, and Fort Worth, Texas found that people experiencing homelessness who used the ED had an average of 3.82 and 3.29 ED visits, respectively [Amato S, Nobay F, Amato DP, Abar B, Adler D. Sick and unsheltered: homelessness as a major risk factor for emergency care utilization. Am J Emerg Med. Mar 2019;37(3):415-420. [CrossRef] [Medline]33,Holmes CT, Holmes KA, MacDonald A, et al. Dedicated homeless clinics reduce inappropriate emergency department utilization. J Am Coll Emerg Physicians Open. 2020;1(5):829-836. [CrossRef] [Medline]34]. These numbers align with recent estimates from the National Hospital Ambulatory Medical Care Survey that found an ED visit rate of 310 per 100 persons per year in 2020‐2021[Schappert SM, Santo L. Emergency department visits by homeless status and sex: United States, 2016-2021. Natl Health Stat Report. Jun 2024;(204):1-21. [Medline]37]. Estimates of inpatient visits among people experiencing homelessness in Texas are more limited and appear higher than numbers from other jurisdictions. A study of veterans in Pittsburgh, Pennsylvania, estimated the average number of inpatient visits at 0.7 (SD 1.6) among those who were hospitalized in 2012‐2013, while single-center studies in Boston, Massachusetts, and Seattle, Washington State, found slightly higher numbers (>2) [Lin WC, Bharel M, Zhang J, O’Connell E, Clark RE. Frequent emergency department visits and hospitalizations among homeless people with Medicaid: implications for Medicaid expansion. Am J Public Health. Nov 2015;105 Suppl 5(Suppl 5):S716-S722. [CrossRef] [Medline]40,Srebnik D, Connor T, Sylla L. A pilot study of the impact of housing first-supported housing for intensive users of medical hospitalization and sobering services. Am J Public Health. 2013;103(2):316-321. [CrossRef] [Medline]48], which align with research showing a high risk of readmission among people experiencing homelessness [Miyawaki A, Hasegawa K, Figueroa JF, Tsugawa Y. Hospital readmission and emergency department revisits of homeless patients treated at homeless-serving hospitals in the USA: observational study. J Gen Intern Med. Sep 2020;35(9):2560-2568. [CrossRef] [Medline]2,Banerjee S, Yassin M, Dyer WT, Thomas TW, Rodriguez LA, Schmittdiel J. Hospital readmissions among patients experiencing homelessness: an electronic health record data study. Perm J. Mar 15, 2024;28(1):55-61. [CrossRef] [Medline]3]. Using these health care utilization numbers, we calculated an average health care cost comparable with previously published estimates of the cost of care among people experiencing homelessness [Buck DS, Brown CA, Mortensen K, Riggs JW, Franzini L. Comparing homeless and domiciled patients’ utilization of the Harris County, Texas public hospital system. J Health Care Poor Underserved. 2012;23(4):1660-1670. [CrossRef] [Medline]35,O’Toole TP, Johnson EE, Borgia M, et al. Population-tailored care for homeless veterans and acute care use, cost, and satisfaction: a prospective quasi-experimental trial. Prev Chronic Dis. Feb 15, 2018;15:E23. [CrossRef] [Medline]49,Mitchell MS, León CLK, Byrne TH, Lin WC, Bharel M. Cost of health care utilization among homeless frequent emergency department users. Psychol Serv. 2017;14(2):193-202. [CrossRef] [Medline]50]. Additional research is needed to understand the health care use and costs among people experiencing homelessness.

This study not only provides insight to the cost-benefit of the iCAN mHealth intervention, but also highlights the scalability and sustainability of an mHealth intervention like iCAN in a metropolitan area. Including a budget impact analysis of iCAN demonstrates that expanding the services provided by iCAN over a 5-year period is both possible and cost-saving. While existing literature on the economic implications of mHealth interventions exists, the majority of these studies did not conduct formal budget impact analyses to determine the sustainability of implementing an intervention on a larger scale [Gentili A, Failla G, Melnyk A, et al. The cost-effectiveness of digital health interventions: a systematic review of the literature. Front Public Health. 2022;10:787135. [CrossRef] [Medline]13,Iribarren SJ, Cato K, Falzon L, Stone PW. What is the economic evidence for mHealth? A systematic review of economic evaluations of mHealth solutions. Plos one. 2017;12(2):e0170581. [CrossRef] [Medline]44]. Our economic evaluation and budget impact analysis balances both real-world data with necessary assumptions on a realistic scale, and many of the assumptions used in this study can be replaced with more specific real-world data after the iCAN RCT has concluded.

This economic evaluation and budget impact analysis provides insightful information in an emerging field where concrete data are lacking in several aspects. In published studies conducting budget impact analyses, the interventions being studied are typically medications or treatment protocols, not multicomponent behavioral health interventions [Avanceña ALV, Brody C, Chhoun P, Tuot S, Yi S. Connecting female entertainment workers in Cambodia to health care services using mHealth: economic evaluation of mobile link. JMIR Form Res. Jul 25, 2024;8:e52734. [CrossRef] [Medline]21,Faleiros DR, Álvares J, Almeida AM, et al. Budget impact analysis of medicines: updated systematic review and implications. Expert Rev Pharmacoecon Outcomes Res. 2016;16(2):257-266. [CrossRef] [Medline]51-Luo Z, Ruan Z, Yao D, Ung COL, Lai Y, Hu H. Budget impact analysis of diabetes drugs: a systematic literature review. Front Public Health. 2021;9:765999. [CrossRef] [Medline]54]. While there are dozens of economic evaluations of mHealth interventions, there are very few formal budget impact analyses associated with these economic evaluations [Gentili A, Failla G, Melnyk A, et al. The cost-effectiveness of digital health interventions: a systematic review of the literature. Front Public Health. 2022;10:787135. [CrossRef] [Medline]13,Iribarren SJ, Cato K, Falzon L, Stone PW. What is the economic evidence for mHealth? A systematic review of economic evaluations of mHealth solutions. Plos one. 2017;12(2):e0170581. [CrossRef] [Medline]44]. Our economic evaluation and budget impact analysis aims to fill this gap about mHealth interventions and the economic scalability and sustainability associated with expanding the services provided.

Limitations

The primary limitations of this study involve the assumptions made in the economic evaluation. The costs associated with the iCAN intervention were estimated from expenditure data from the RCT, which likely overestimate the actual costs of the intervention if implemented in real-world setting due to costs required to ensure accurate trial design and adherence to protocol [Heapy AA, Driscoll MA, Buta E, et al. Co-operative pain education and self-management (copes) expanding treatment for real-world access (extra): pragmatic trial protocol. Pain Med. 2020;21(Suppl 2):S21-S28. [CrossRef] [Medline]20]. We addressed this issue by adjusting the fixed costs included in our budget impact analysis, however, other economies of scale are potentially still excluded from our analysis. Health care costs related to ED and inpatient visits were estimated using national health care expenditure data (MEPS-HC) because such data were not available through the trial or for Travis County specifically. With possible variations in health care cost and utilization among people experiencing homelessness, our probabilistic sensitivity analyses explored the impact of uncertainty on our findings and indeed found a wide range of savings thresholds for iCAN. This suggests iCAN’s economic value will be highly influenced by the change in health care costs and utilization of people experiencing homelessness who receive the intervention. Finally, we also had to make simplifying assumptions in the budget impact analysis, including the current size and growth of the people experiencing homelessness population in Travis County over the next 5 years. Our budget impact analysis can be easily updated with more precise inputs to understand the financial aspects of expanded access to iCAN.

Conclusions

This exploratory economic evaluation gives estimates of the cost of the iCAN mHealth intervention while exploring the cost-savings and budget impact of implementing the iCAN mHealth intervention on a larger scale. By using data from the iCAN RCT and other available resources, this economic evaluation determined that implementing the iCAN mHealth intervention for people experiencing homelessness in a metropolitan area provides financial cost-benefit if 1 hospitalization or 2 ED visits can be avoided. Future studies should explore the feasibility of implementing the iCAN mHealth intervention using data from the completed iCAN RCT to limit uncertainty in the cost of scaling up the intervention. Health care payers should examine the benefits of implementing mHealth interventions like this one to prevent unnecessary health care utilization and the associated costs among people experiencing homelessness.

Acknowledgments

Portions of the content (ie, the randomized controlled trial described in the methods) of this manuscript are funded under grant 1R18 HS027750-01 from the Agency for Healthcare Research and Quality (AHRQ), US Department of Health and Human Services (HHS). The authors are solely responsible for the contents, findings, and conclusions, which do not necessarily represent the views of AHRQ. Readers should not interpret any statement in this report as an official position of AHRQ or of HHS. None of the authors have any affiliation or financial involvement that conflict with the material presented in this report. Portions of this manuscript were previously presented as abstracts and posters at the St. David’s Center for Health Promotion and Disease Prevention Research in Underserved Populations Conference at the University of Texas School of Nursing in March 2023 and the AcademyHealth Annual Research Meeting in Seattle, WA, in June 2023.

Data Availability

The datasets generated during and analyzed during this study are available from the corresponding author on reasonable request.

Conflicts of Interest

None declared.

Multimedia Appendix 1

Annual emergency department and inpatient health care utilization among people experiencing homelessness.

DOCX File, 16 KB

Multimedia Appendix 2

Scenarios explored in the cost analysis of Interactive Care Coordination and Navigation, an mHealthmobile health intervention for people experiencing homelessness in the United States.

DOCX File, 15 KB

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CHEERS: Consolidated Health Economic Evaluation Reporting Standards
ED: emergency department
HIE: health information exchange
I-TECH: International Training and Education Center for Health
iCAN: Interactive Care Coordination and Navigation
ISPOR: The International Society for Pharmacoeconomics and Outcomes Research
MEPS-HC: Medical Expenditure Panel Survey-Household Component
mHealth: mobile health
PPPY: per participant per year
RCT: randomized controlled trial


Edited by Amaryllis Mavragani; submitted 01.08.24; peer-reviewed by Laura Pirhonen, Martha P Montgomery; final revised version received 13.01.25; accepted 16.01.25; published 18.03.25.

Copyright

© Hannah P McCullough, Leticia R Moczygemba, Anton L V Avanceña, James O Baffoe. Originally published in JMIR Formative Research (https://formative.jmir.org), 18.3.2025.

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