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Schizophrenia is a complex psychiatric condition with a large disease burden and is one of the top causes of disability globally, presenting considerable challenges for patients, caregivers, and health care systems [1-4]. In the United States, people living with schizophrenia have a severely reduced life expectancy (losing ≈28.5 years of life) [5] and significantly higher mortality rate [6] than the general population.
JMIR Res Protoc 2025;14:e81293
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Schizophrenia can lead to high functional disability and is associated with a heavy economic burden worldwide. The World Health Organization lists it as one of the top 10 conditions in terms of the global burden of disease [1,2]. Schizophrenia is a disease characterized by impairments in cognitive functions.
JMIR Serious Games 2025;13:e69116
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Psychotic illnesses such as schizophrenia and related conditions are a major issue for public health care systems; they cause severe disability and are expensive to treat. As the illness becomes manifest during adolescence or young adulthood, nonspecific signs such as anxiety, depression, and emerging psychotic features form a prelude to the full psychotic syndrome that may last for months or even years before patients seek help or receive treatment.
JMIR Res Protoc 2025;14:e74408
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Participants were eligible if they were aged 18‐40 and had experienced a FEP in the 24 months prior to entering the study as defined by a DSM-IV diagnosis of schizophrenia, schizophreniform disorder, schizoaffective disorder, or delusional disorder based on the Structured Clinical Interview for DSM-IV (SCID-I) [22]. Finally, participants were required to have access to a smartphone with internet data.
J Med Internet Res 2025;27:e71989
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Schizophrenia is a chronic mental disorder that often negatively affects the daily life of individuals living with the condition, including their community and social life, due to positive and negative symptoms as well as cognitive dysfunction [1]. The main treatment for schizophrenia is pharmacotherapy, with antipsychotics primarily improving positive symptoms but affecting negative symptoms and cognitive dysfunction less [2].
JMIR Form Res 2025;9:e70916
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Determinant Factors of Stress in Caregivers of Patients With Schizophrenia: Cross-Sectional Study
The burden of caregiving was quantified using Zarit’s Caregiver Burden [25], and caregiver knowledge was measured through the Knowledge Assessment Schizophrenia Test [26,27]. Additionally, medication noncompliance among patients with schizophrenia was assessed using the Medication Compliance Report Scale [28]. Each instrument was rigorously validated at the Bungoro Health Center, Pangkep Regency, to ensure high reliability and validity (Table 1).
JMIR Form Res 2025;9:e70648
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In the same vein, data mining and visualization are thus important in the case of schizophrenia, where understanding behavioral patterns and predicting relapse significantly impact patient outcomes.
The current literature strongly supports the notion that data visualizations have the potential to improve clinicians’ engagement and effectively communicate trends in patient data [13,14].
JMIR Form Res 2025;9:e70073
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For instance, individuals with schizophrenia often exhibit disturbances in their speech patterns, characterized by disorganized syntax and impaired semantic coherence [3]. Similarly, individuals with borderline personality disorder (BPD) have higher levels of overall expressive language impairment, as well as decreased syntactic and lexical complexity [4].
Furthermore, quantitative analysis of language usage can aid in tracking disease progression and treatment response.
JMIR AI 2025;4:e67369
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Suicide is a common cause of premature mortality among people living with schizophrenia [3,4] and a recent systematic review has reported a point prevalence of nearly 30% of SIs in people with schizophrenia [5].
Most of the empirical research on the risks of suicidality includes cross-sectional or retrospective studies that distinguish the characteristics between people who experience SIs or suicidal behavior, and those who do not [6-8].
JMIR Form Res 2025;9:e67745
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The PRISM study aimed to investigate social withdrawal in 2 brain disorders, schizophrenia and probable AD [32,33].
J Med Internet Res 2025;27:e64007
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