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Skip search results from other journals and go to results- 47 JMIR Mental Health
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Psychosis is the distinguishing feature of schizophrenia spectrum disorders and a frequent manifestation of mood and substance use disorders [1]. It is characterized by alterations in thoughts and perceptions, often taking the form of positive symptoms such as delusions, hallucinations [2], and disorganized thinking [3], as well as negative symptoms such as blunted affect, poverty of speech, and withdrawal from social and occupational activities [4].
JMIR Res Protoc 2025;14:e63405
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To showcase the proposed methodology, we developed a GPT-4–powered schizophrenia informational chatbot, hereafter referred to as CAFIbot, which conveys the content of the Learning to Live With Schizophrenia manual. This manual was produced by the Global Alliance of Mental Illness Advocacy Network Europe patient advocacy group [11], who we are collaborating with in an ongoing clinical project (called TRUSTING) involving patients with mental health problems [12].
JMIR AI 2025;4:e69820
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Sedentary lifestyle and low aerobic fitness are highly ubiquitous among individuals with schizophrenia [1,2] and are associated with a wide range of medical and psychiatric health indicators including cardiopulmonary and metabolic problems [3-5], high symptom burden, and depression [6], as well as poor neurocognition and daily functioning [1].
JMIR Ment Health 2025;12:e68251
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Movement data estimated from a 3-axis accelerometer were negatively correlated with negative symptoms assessed with the Positive and Negative Syndrome Scale (PANSS) in patients with schizophrenia [17]. The number of steps was negatively correlated with PANSS positive-factor, negative-factor, general subscales, and total score, in patients with schizophrenia in an inpatient setting [18].
JMIR Mhealth Uhealth 2025;13:e56185
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The estimated lifetime prevalence of schizophrenia is 0.59%, according to a secondary analysis of the 2019 cross-sectional Japan National Health and Wellness Survey [6]. However, this study may produce underestimation since it only depended on physician diagnoses. Individuals with schizophrenia hardly self-identify as having schizophrenia because of stigma and lack of awareness of schizophrenia and its symptoms [7-13].
JMIR Form Res 2025;9:e66330
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Several studies suggest that there is an association between a positive therapeutic alliance and improved outcomes in people with mental illness, including schizophrenia.
JMIR Ment Health 2025;12:e64959
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Attitudes toward people with psychotic disorders were measured with the modified attitudes toward people with schizophrenia scale [36]. The 7-item scale is measured on a 9-point Likert scale ranging from 1 to 9. Total scores range from 7 to 63, with higher scores indicating better attitudes. Items 1 and 2 are reverse coded. An example item is “How much do you personally care about the plight of people with schizophrenia?” The internal consistency Cronbach alpha ranges from 0.76 to 0.79 [36].
JMIR Ment Health 2025;12:e66925
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The costs and burdens of schizophrenia spectrum psychosis and bipolar disorder are huge and often neglected in research [1,2]. Digital mental health interventions (DMHIs) can help people with psychosis or bipolar disorder monitor, manage, and improve their symptoms and health [3-6].
JMIR Ment Health 2025;12:e65246
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Schizophrenia is a psychiatric disorder that affects approximately 1% of the total population and is typically prevalent between the ages of 16 and 30 years [1,2]. Pharmacotherapy with antipsychotic drugs is the standard treatment for schizophrenia. Moreover, cognitive behavioral therapy, a psychological intervention, is recommended by the National Institute of Health and Clinical Excellence (NICE) [3].
JMIR Form Res 2025;9:e59540
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We found that AU02 is significantly activated in people with schizophrenia compared with other groups. For mean values of the action units, this implies that AU02 is significantly less for the control group than the ASD group. For AU06, schizophrenia is significantly less than the control group. For AU12, it is more evident that schizophrenia is significantly less than either the control or ASD group. Regarding SD, people with ASD have significantly activated AU02 compared with the control group.
JMIR Form Res 2025;9:e59261
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