e.g. mhealth
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These include monofilament tests, brief questionnaires (eg, the Michigan Neuropathy Screening Instrument) [11], and vibration testing, among others. Collectively, these instruments have been criticized for their lack of accuracy and vulnerability to human error and biases that lead to missed opportunities for follow-up [9,10].
Validated tools are needed to facilitate risk detection and reduce diagnostic uncertainty in the management of diabetic polyneuropathy [12-16].
JMIR Diabetes 2025;10:e60141
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We evaluated our method by obtaining the Kaplan-Meier curves based on symptoms that were normalized to peripheral neuropathy (PN). In addition, we also evaluated the duration of PN.
This study used data from all patients diagnosed with breast cancer (N=2289) treated at the Kyoto University Hospital between 2019 and 2021. The patient data consisted of 2 types of medication orders (structured data) and 6 types of texts written in Japanese (unstructured data).
JMIR Med Inform 2024;12:e58977
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Edit sentence to read: “…and peripheral nerves, causing neuropathy and severe disability, consequently resulting in social exclusion and stigmatization.”
Edit sentence to read: “…new child cases [3], with a grade 2 disability rate of about 15% for the past…”
Edit sentence to read: “Thirty to fifty percent of…”
Edit sentence to read: “Ulcers usually occur in anesthetic feet, and will heal slowly with routine therapy, however have a tendency to recur [6].”
JMIRx Med 2024;5:e56498
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If diabetes is excluded, it may be good to also exclude other known reasons for peripheral neuropathy (eg, vitamin B deficiencies)
7. Are signs of infection also monitored, assessed, or outcome measures?
8. Please explain more on the swabs: what kind of swab is it and what is tested, if this is not part of the research project? In general, it is better to take a routine swab to test for infection (bacterial growth) prior to inclusion instead of prior to randomization, as infection is an exclusion criteria.
JMIRx Med 2024;5:e57310
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Edit sentence to read: “…and peripheral nerves, causing neuropathy and severe disability, consequently resulting in social exclusion and stigmatization.”
Response: Done.
Edit sentence to read: “…new child cases [3], with a grade 2 disability rate of about 15% for the past…”
Response: Done.
Edit sentence to read: “Thirty to fifty percent of…”
Response: Done.
Edit sentence to read: “Ulcers usually occur in anesthetic feet, and will heal slowly with routine therapy, however have a tendency to recur [6].”
JMIRx Med 2024;5:e56442
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The disease morbidity is characterized by damage to the skin and peripheral nerves, causing neuropathy and severe disability and consequently resulting in social exclusion and stigmatization [2]. Leprosy is preventable and treatable with multidrug therapy but remains endemic in many communities of people living in poverty and with poor hygiene [2].
JMIRx Med 2024;5:e50970
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Neuropathy is another common symptom of either cancer treatment or, less frequently, cancer itself and can be acute or chronic in nature [6]. There are a wide range of ways in which patients describe this experience, although peripheral neuropathy is often described as the sensation of shooting or stabbing pain and tingling or loss of feeling in the affected areas. This can impact many activities, such as walking, balance, and mood [6].
JMIR Res Protoc 2024;13:e47745
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Neuropathic foot ulcers are a common complication of peripheral neuropathy. Among different etiologies leading to peripheral neuropathy, foot ulcers related to diabetic peripheral neuropathy (ie, diabetic foot ulcers [DFUs]) are the most prevalent, expensive, and deadly complications in health care [1]. Up to a third of the cost of diabetes is estimated to be related to foot care [2]. It has been reported that 10% of ulcers become infected and that 20% of infected ulcers result in an amputation [3].
JMIR Diabetes 2024;9:e46096
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The introduction of new technologies for the remote temperature monitoring of patients with diabetes and neuropathy at risk of ulcer formation suggests more patients may be able to use temperature monitoring in their daily lives. One such technology, Siren Socks (Siren Care), is a smart sock worn by patients; it has a regular connection to the cloud for the capture and sharing of temperature data with health care professionals. Siren Socks are available for patients under the supervision of a physician.
JMIR Form Res 2022;6(4):e31870
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The qualification for subscribing to the smart socks was the diagnosis of peripheral neuropathy. The inclusion criteria were patients using the smart sock temperature monitoring device for at least 1 day, those who were at participating sites, and those who consented to the registry, as per the IRB-approved protocol. The first calendar month of utilization was excluded due to the variability in which days of the month patients began using the RPM device.
JMIR Form Res 2022;6(3):e32934
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