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Automated Process for Monitoring of Amiodarone Treatment: Development and Evaluation

Automated Process for Monitoring of Amiodarone Treatment: Development and Evaluation

However, careful follow-up is necessary during treatment due to potentially serious adverse effects and toxic reactions in the thyroid gland, liver, lung, and heart. Approximately 15% of patients will experience adverse effects during the first year of amiodarone use and 50% during long-term treatment, most often thyroid and liver dysfunction [1].

Birgitta I Johansson, Jonas Landahl, Karin Tammelin, Erik Aerts, Christina E Lundberg, Martin Adiels, Martin Lindgren, Annika Rosengren, Nikolaos Papachrysos, Helena Filipsson Nyström, Helen Sjöland

J Med Internet Res 2025;27:e65473

Virtual Reality in Clinical Teaching and Diagnostics for Liver Surgery: Prospective Cohort Study

Virtual Reality in Clinical Teaching and Diagnostics for Liver Surgery: Prospective Cohort Study

In the second part, we presented the respective segmented 3 D model of the liver converted from MRI data and visualized in a VR simulation with VR goggles (HTC Vive Pro). In our experimental setup, participants found themselves in a simulated operating room with a virtual representation of a body on the operating table (Figure 1).

Joshua Preibisch, Navid Tabriz, Maximilian Kaluschke, Dirk Weyhe, Verena Uslar

JMIR XR Spatial Comput 2024;1:e60383

Identification of COVID-19–Associated Hepatitis in Children as an Emerging Complication in the Wake of SARS-CoV-2 Infections: Ambispective Observational Study

Identification of COVID-19–Associated Hepatitis in Children as an Emerging Complication in the Wake of SARS-CoV-2 Infections: Ambispective Observational Study

CAH-C’s form of transient hepatitis is different from already familiar liver injury phenotypes and occasionally witnessed persistent diseases in children with COVID-19. In the current context, cases of severe pediatric hepatitis of unknown origin have affected at least 169 children in nearly 12 countries, with at least 16 children having required liver transplantation [17].

Sumit Kumar Rawat, Ajit Anand Asati, Nitu Mishra, Ashish Jain, Radha Kanta Ratho

JMIRx Med 2024;5:e48629

Establishment and Evaluation of a Noninvasive Metabolism-Related Fatty Liver Screening and Dynamic Monitoring Model: Cross-Sectional Study

Establishment and Evaluation of a Noninvasive Metabolism-Related Fatty Liver Screening and Dynamic Monitoring Model: Cross-Sectional Study

Nonalcoholic fatty liver disease (NAFLD) is regarded as an important cause of liver disease, affecting more than 25% of the general population worldwide; more than 50% of patients with NAFLD also have dysmetabolism [1,2]. In 2020, experts redefined NAFLD as metabolically associated fatty liver disease (MAFLD), and much emphasis was placed on the presence of metabolic-related diseases or dysfunction [3-5].

Jiali Ni, Yong Huang, Qiangqiang Xiang, Qi Zheng, Xiang Xu, Zhiwen Qin, Guoping Sheng, Lanjuan Li

Interact J Med Res 2024;13:e56035

Care Integration for Hepatitis C Virus Treatment Through Facilitated Telemedicine Within Opioid Treatment Programs: Qualitative Study

Care Integration for Hepatitis C Virus Treatment Through Facilitated Telemedicine Within Opioid Treatment Programs: Qualitative Study

The benefit of facilitated telemedicine is bidirectional; the telemedicine provider collaborated with the onsite clinician to perform physical examinations as indicated, and the onsite clinician achieved enhanced job satisfaction through the application of new and enhanced clinical assessments to gauge liver health. Participants further labeled the facilitation as a “warm handoff” and “seamless” transition to the telemedicine provider.

Suzanne S Dickerson, Saliyah J George, Ana Ventuneac, Arpan Dharia, Andrew H Talal

J Med Internet Res 2024;26:e53049

Impact of an Automated Population-Level Cirrhosis Screening Program Using Common Pathology Tests on Rates of Cirrhosis Diagnosis and Linkage to Specialist Care (CAPRISE): Protocol for a Pilot Prospective Single-Arm Intervention Study

Impact of an Automated Population-Level Cirrhosis Screening Program Using Common Pathology Tests on Rates of Cirrhosis Diagnosis and Linkage to Specialist Care (CAPRISE): Protocol for a Pilot Prospective Single-Arm Intervention Study

Liver cirrhosis is a major global public health threat; from 1990 to 2017, the global estimate of compensated cirrhosis prevalence increased from 66 million cases to 112 million cases [1], and liver cirrhosis directly causes millions of deaths each year due to liver failure and liver cancer [2,3]. Without timely treatment of chronic liver disease of any cause, individuals are at risk of developing liver cirrhosis [4].

Joan Ericka Flores, Christina Trambas, Natasha Jovanovic, Alexander J Thompson, Jessica Howell

JMIR Res Protoc 2024;13:e56607

User Engagement, Acceptability, and Clinical Markers in a Digital Health Program for Nonalcoholic Fatty Liver Disease: Prospective, Single-Arm Feasibility Study

User Engagement, Acceptability, and Clinical Markers in a Digital Health Program for Nonalcoholic Fatty Liver Disease: Prospective, Single-Arm Feasibility Study

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the world [1]. NAFLD is defined as >5% fat in the liver (steatosis) among people who drink moderate amounts or no alcohol and have no other chronic liver diseases [2]. NAFLD reflects a spectrum of liver pathologies, ranging from simple steatosis to a more severe condition called nonalcoholic steatohepatitis (NASH), which includes inflammation and potential scarring of the liver [3].

Sigridur Björnsdottir, Hildigunnur Ulfsdottir, Elias Freyr Gudmundsson, Kolbrun Sveinsdottir, Ari Pall Isberg, Bartosz Dobies, Gudlaug Erla Akerlie Magnusdottir, Thrudur Gunnarsdottir, Tekla Karlsdottir, Gudlaug Bjornsdottir, Sigurdur Sigurdsson, Saemundur Oddsson, Vilmundur Gudnason

JMIR Cardio 2024;8:e52576