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It is estimated that one-third of patients with COPD who have been hospitalized due to an acute exacerbation are readmitted within 1 year [8,9]. Consequently, preventing exacerbations is an important part of COPD care. Essential to preventing exacerbations and improving health outcomes is optimizing self-management of patients with COPD [10-12].
JMIR Form Res 2024;8:e57108
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There is evidence to suggest that reducing delays in treatment and correct identification of exacerbations can reduce the severity of exacerbations, improve health-related quality of life (HRQo L), and reduce recovery time after an exacerbation. Wilkinson et al [15] found that a longer time to treatment in AECOPD was associated with an increase in the recovery time of exacerbation symptoms [15].
J Med Internet Res 2024;26:e52143
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Exploring Machine Learning Applications in Pediatric Asthma Management: Scoping Review
In addition, factors such as systemic and interpersonal racial and ethnic discrimination, suboptimal asthma control, and environmental triggers play a crucial role in exacerbation development [9,10]. Specifically, aeroallergen exposure or sensitization and concurrent viral infections have been shown to significantly increase exacerbation risks [11-13]. Given this complex interplay of factors, accurately predicting severe asthma exacerbations in children remains a challenge.
JMIR AI 2024;3:e57983
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Hospitalization was defined as hospitalizations resulting from disease exacerbation. The primary time points for the analysis were baseline and the end of the intervention.
The continuous variables included the 6 MWD, CAT score, and SGRQ score. The m MRC dyspnea scale score was a categorical variable, and it was calculated as a continuous value. Hospitalization resulting from disease exacerbation was a dichotomous variable. The variables at the time of follow-up were compared between groups.
JMIR Mhealth Uhealth 2024;12:e41753
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This approach led us to include clinical terms associated with asthma attacks, encompassing concepts such as asthma exacerbation, asthma control, asthma management, and hospitalization. In addition, we integrated technical terminology related to ML, incorporating terms such as artificial intelligence, supervised methods, and deep learning (DL). All the keywords that we used in the search strategy can be found in Multimedia Appendix 1 [4,11,21-35].
JMIR AI 2023;2:e46717
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Over the past years, research has increasingly focused on exacerbation-related self-management interventions, as they have shown to have positive effects on quality of life and hospital admissions [9,10]. In this context, the use of mobile health (m Health) is considered to be promising to engage patients in their own health and to change health behaviors [11-13].
Current e Health and m Health interventions often focus on telemonitoring strategies to reduce the impact of exacerbations [14-19].
JMIR Form Res 2020;4(11):e21577
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An exacerbation is defined as a sustained worsening of patients’ respiratory symptoms, which are beyond normal day-to-day variability and may warrant medical treatment [8]. The absence of an adequate imminent exacerbation marker requires a focus on supporting patients with COPD in developing self-management skills to reduce the impact of exacerbations [9].
J Med Internet Res 2020;22(6):e15449
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Similarly, LAMAs have complemented medium to high doses of ICS/LABA resulting in improved asthma control scores, especially for patients with severe exacerbation [4,5].
However, for most severe cases with uncontrolled asthma, the need for a simplified device to deliver rescue and maintenance bronchodilators administered at home or in ambulatory settings to treat or prevent moderate or severe exacerbations that requires a minimal inspiratory flow rate remains unmet.
Interact J Med Res 2020;9(2):e17863
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