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Digital Mental Health Interventions for the Prevention and Treatment of Social Anxiety Disorder in Children, Adolescents, and Young Adults: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Digital Mental Health Interventions for the Prevention and Treatment of Social Anxiety Disorder in Children, Adolescents, and Young Adults: Systematic Review and Meta-Analysis of Randomized Controlled Trials

However, other studies found no difference between SAD-specific and transdiagnostic anxiety interventions for children and adolescents with SAD [55,56]. Thus, it would be relevant to compare the effects of DMHIs that specifically target SAD and those that target anxiety disorders in general. To the best of our knowledge, no systematic review and meta-analysis has investigated the effect of DMHIs on social anxiety in children and adolescents specifically.

Noemi Walder, Alessja Frey, Thomas Berger, Stefanie Julia Schmidt

J Med Internet Res 2025;27:e67067

Artificial Intelligence–Based Mobile Phone Apps for Child Mental Health: Comprehensive Review and Content Analysis

Artificial Intelligence–Based Mobile Phone Apps for Child Mental Health: Comprehensive Review and Content Analysis

Concerns regarding mental health, particularly among children—defined as individuals younger than 18 years of age [2]—have garnered increasing attention in recent years. Around the world, 1 in 7 children experiences mental health conditions, yet many more remain largely unrecognized and untreated [1].

Fan Yang, Jianan Wei, Xuejun Zhao, Ruopeng An

JMIR Mhealth Uhealth 2025;13:e58597

Piloting the Extension for Community Healthcare Outcomes (ECHO) Pediatric Oncology Telehealth Education Program in Western Kenya: Implementation Study

Piloting the Extension for Community Healthcare Outcomes (ECHO) Pediatric Oncology Telehealth Education Program in Western Kenya: Implementation Study

Over the past decade, efforts have been made to identify health care disparities affecting children in Sub-Saharan Africa [1]. It is recognized that pediatric cancer rates are far below what would be anticipated based on treatment records at large referral centers [2]. The western regions of Kenya are home to approximately 24 million citizens, which corresponds to 10 million children under the age of 15 [3].

Tyler Severance, Gilbert Olbara, Festus Njuguna, Martha Kipng'etich, Sandra Lang'at, Maureen Kugo, Jesse Lemmen, Marjorie Treff, Patrick Loehrer, Terry Vik

JMIR Form Res 2025;9:e59776

Collecting Real-Life Psychophysiological Data via Wearables to Better Understand Child Behavior in a Children’s Psychiatric Center: Mixed Methods Study on Feasibility and Implementation

Collecting Real-Life Psychophysiological Data via Wearables to Better Understand Child Behavior in a Children’s Psychiatric Center: Mixed Methods Study on Feasibility and Implementation

In total, 18 children from the clinic and 12 children from the day care unit were included (see Study Population subsection in the Results section for further details). The majority of the children attended a special education school located adjacent to the treatment center for at least a few hours each day. No inclusion or exclusion criteria were formulated. The ethics approval was reviewed by the Medical Research Ethics Committee at the UMCU, the Netherlands.

Karin Hagoort, Kirsten Smeets, Saskia Koldijk, Floortje Scheepers, Fleur Velders

JMIR Form Res 2025;9:e65559

Supporting Medication Adherence in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplant Using the BMT4me mHealth App: Mixed Methods Usability Study

Supporting Medication Adherence in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplant Using the BMT4me mHealth App: Mixed Methods Usability Study

However, such interventions have yet to be tested to promote medication adherence among children in the acute phase post-HCT (ie, hospital discharge to day 100) [30]. This paper reports a longitudinal mixed methods pilot study examining the usability of a m Health intervention (BMT4me) with caregivers of children in the acute phase following HCT. This intervention helps caregivers to record and track their child’s medications, set reminders, report symptoms, and take notes on their child’s progress.

Mariam Kochashvili, Parishma Guttoo, Emre Sezgin, Ahna Pai, Rajinder Bajwa, Wendy Landier, Cynthia Gerhardt, Micah Skeens

JMIR Cancer 2025;11:e66847

An Exergames Program for Adolescents With Type 1 Diabetes: Qualitative Study of Acceptability

An Exergames Program for Adolescents With Type 1 Diabetes: Qualitative Study of Acceptability

Recruitment occurred at the Yale Children’s Diabetes Center and through an internet posting circulated on Facebook by the nonprofit Children with Diabetes (T1-Today, Inc) which provides education and support to youths with T1 D and their families. This study was approved by the Institutional Review Board of the Yale Human Investigation Committee (#2000030105).

Selene S Mak, Laura M Nally, Juanita Montoya, Rebecca Marrero, Melissa DeJonckheere, Kevin L Joiner, Soohyun Nam, Garrett I Ash

JMIR Diabetes 2025;10:e65665

Factors Influencing Virtual Reality as a Distraction Tool for Venipuncture in Children: Observational Pilot Feasibility Study

Factors Influencing Virtual Reality as a Distraction Tool for Venipuncture in Children: Observational Pilot Feasibility Study

A recent systematic review and meta-analysis [10] collated 11 randomized controlled trials in children under 12 years of age to conclude that VR was more useful than other nonpharmacological methods to relieve pain and anxiety for various procedures in children. Another recent meta-analysis [11] of 10 randomized controlled trials evaluated the efficacy of VR use in children aged 3 to 12 years to conclude favorably on the efficacy and benefit in pediatric venipuncture.

Chris Worth, Leyi Yang, Catherine Fullwood, Indraneel Banerjee

JMIR Serious Games 2025;13:e66656

Hospitalization and Mortality in Brazilian Children and Adolescents Due to COVID-19: Retrospective Study

Hospitalization and Mortality in Brazilian Children and Adolescents Due to COVID-19: Retrospective Study

COVID-19 is currently one of the most important medical challenges as it affects the entire population, with children and adolescents being infected as easily as adults; children and adolescents often remain asymptomatic or have mild complaints due to their immature immune systems [1].

Ana Carolina Pereira de Godoy, Reinaldo Bulgarelli Bestetti

JMIR Pediatr Parent 2025;8:e67546

Assessing the Impact of a Telemedicine Program on Caregivers of Children With Complex Chronic Conditions: Pre-Post Intervention Study

Assessing the Impact of a Telemedicine Program on Caregivers of Children With Complex Chronic Conditions: Pre-Post Intervention Study

In high-income countries, children with a complex chronic condition (CCC) represent 0.67%‐5% of the pediatric population; however, they consume up to 40% of total health expenditure, involving a high level of care both in and out of hospital, primary care, and non-health services [5-9]. The prevalence of life-threatening or life-limiting illnesses has increased in recent decades, with an estimated 61.1 per 10,000 children aged 1‐19 years in the United Kingdom.

Aurora Madrid-Rodríguez, María José Peláez-Cantero, Alfonso Lendínez-Jurado, Ana Suárez-Carrasco, Elena Godoy-Molina, Antonia Gámez-Ruiz, Ana Corripio-Mancera, Yolanda Ramón-Telo, Ana García-Ruiz, Isabel Leiva-Gea

JMIR Pediatr Parent 2025;8:e62953

Parents’ Motivations for Calling an Out-of-Hours Helpline: Qualitative Study

Parents’ Motivations for Calling an Out-of-Hours Helpline: Qualitative Study

Young children often fall ill, leading to more out-of-hours health care usage compared with other patient age groups [1-3]. Fortunately, severe illness in children is rare [4]. In a study of 16,000 children under 5 years admitted to a pediatric department with fever, only 7% had a severe infection [5]. The high rate of health care usage is often driven by a fear of making the wrong decisions and failing to recognize severe symptoms, particularly in young children [5-10].

Liv Borch-Johnsen, Fredrik Folke, Marianne Sjølin Frederiksen, Morten Schrøder, Gorm Greisen, Stine Lund, Vibeke Zoffmann, Caroline Gren, Tine Tjørnhøj-Thomsen, Dina Cortes

J Med Internet Res 2025;27:e66780