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A Human-Centered Approach for a Student Mental Health and Well-Being Mobile App: Protocol for Development, Implementation, and Evaluation

A Human-Centered Approach for a Student Mental Health and Well-Being Mobile App: Protocol for Development, Implementation, and Evaluation

A recurrent theme across these sessions was the absence of a personalized, regularly updated medium through which students could effectively engage with available university resources. Although a range of services existed, participants emphasized the need for an integrated system to support continuous search, discovery, and engagement.

Maryam Gholami, David Wing, Manas Satish Bedmutha, Job Godino, Anahi Ibarra, Byron Fergerson, Nicole May, Christopher A Longhurst, Nadir Weibel, Anne Duffy, Heidi Rataj, Karandeep Singh, Kevin Patrick

JMIR Res Protoc 2025;14:e68368

Future Me, a Prospection-Based Chatbot to Promote Mental Well-Being in Youth: Two Exploratory User Experience Studies

Future Me, a Prospection-Based Chatbot to Promote Mental Well-Being in Youth: Two Exploratory User Experience Studies

To address these gaps, we developed “Future Me,” a chatbot prototype that uses GPT-3.5 to facilitate future-oriented thinking by simulating a conversation with the user’s future self. The interaction with Future Me aims to stimulate a future-oriented mindset by strengthening people’s ability and motivation to consider their future and fostering identification with their future self.

Martin Dechant, Eva Lash, Sarah Shokr, Ciarán O'Driscoll

JMIR Form Res 2025;9:e74411

Intervention for Justice-Involved Homeless Veterans With Co-Occurring Substance Use and Mental Health Disorders: Protocol for a Randomized Controlled Hybrid Effectiveness-Implementation Trial

Intervention for Justice-Involved Homeless Veterans With Co-Occurring Substance Use and Mental Health Disorders: Protocol for a Randomized Controlled Hybrid Effectiveness-Implementation Trial

Using a hybrid type 1 effectiveness-implementation design [55], we will test the effectiveness of the MISSION-CJ intervention in a randomized controlled trial (RCT) across 2 large VA health care systems as well as conduct a qualitative evaluation of MISSION-CJ’s implementation.

Kathryn Bruzios, Paige M Shaffer, Daniel M Blonigen, Michael A Cucciare, Michael Andre, Thomas Byrne, Jennifer Smith, David Smelson

JMIR Res Protoc 2025;14:e70750

Current Practice and Expert Perspectives on Cultural Adaptations of Digital Health Interventions: Qualitative Study

Current Practice and Expert Perspectives on Cultural Adaptations of Digital Health Interventions: Qualitative Study

For example, creating a preliminary adaptation design of a mental health intervention will differ drastically when the intervention is delivered physically compared to it being delivered through a mobile phone app that might require expensive and time-consuming software changes.

Vasileios Nittas, Sarah J Chavez, Paola Daniore

JMIR Mhealth Uhealth 2025;13:e59965

Streamlining a Patchwork - Exploring the Challenges of Digital Transformation in Pathology: Ethnographic Study

Streamlining a Patchwork - Exploring the Challenges of Digital Transformation in Pathology: Ethnographic Study

A key analogue practice in pathology that is now being digitized via whole-slide imaging is diagnosis. This means that, instead of examining tissue samples on glass slides under a microscope, the glass slide is scanned as a high-resolution image, and the digital slide is examined on a computer screen. Digitizing this step can be seen as a paradigm shift in the digital transformation of pathology. It affects the entire pathology workflow [6].

Birte Linny Geisler, Ourania Amperidou, Sina Patricia Pauly, Sven Mattern, Christian M Schürch, Claudia Hermann, Christiane Stoffregen, Ilona Steinleitner, Natali Paigin, Claudia Lamß, Falko Fend, Monika A Rieger, Esther Rind, Christine Preiser

J Med Internet Res 2025;27:e63366

Delivering an Electronic Health Record Based Educational Intervention Promoting Peri-Operative Non-Pharmacological Pain Care as Part of a Randomized Controlled Trial: Mixed Method Evaluation of Inpatient Nurses’ Perspectives

Delivering an Electronic Health Record Based Educational Intervention Promoting Peri-Operative Non-Pharmacological Pain Care as Part of a Randomized Controlled Trial: Mixed Method Evaluation of Inpatient Nurses’ Perspectives

These 7 questions were rated on a 10-point numeric rating scale, and participants were provided the anchors, 1=not at all, 10=a great deal. Participants could also select "unable to assess" as a response. Survey items were generated by members of the study team (including nursing professionals, a researcher, and physicians), whose experience helping implement the intervention informed key questions for nursing leadership to assess how implementation was going.

Sarah A Minteer, Cindy Tofthagen, Kathy Sheffield, Susanne Cutshall, Susan Launder, Jane Hein, Mary McGough, Christy M Audeh, Jon C Tilburt, Andrea L Cheville

JMIR Nursing 2025;8:e70332

Impact of the Exposome in Type 1 Diabetes: Protocol for a Scoping Review

Impact of the Exposome in Type 1 Diabetes: Protocol for a Scoping Review

Such a comprehensive understanding is essential for the identification of new strategies for disease prevention and management. Conducting a scoping review is well-suited for this broad research question, as it allows for an exhaustive exploration, particularly for a fragmented research area. Unlike systematic reviews, scoping reviews map existing knowledge, identify research gaps, and comprehensively synthesize the available evidence [27-29].

Maurane Rollet, Gloria A Aguayo, Jean-Pierre Riveline, Emmanuel Cosson, Guy Fagherazzi

JMIR Res Protoc 2025;14:e73424

Exploring the Dilemma of AI Use in Medical Research and Knowledge Synthesis: A Perspective on Deep Research Tools

Exploring the Dilemma of AI Use in Medical Research and Knowledge Synthesis: A Perspective on Deep Research Tools

“Overall, I think Deep Research does produce a good first draft that would probably be readily accepted in a mid-tier journal, but which could be significantly improved with editing and revisions. Perhaps the outputs might improve with better prompts or guidance (eg providing refined outlines and a reference list).”

Ariel Yuhan Ong, David A Merle, Siegfried K Wagner, Pearse A Keane

J Med Internet Res 2025;27:e75666

Bringing Executive Function Testing Online: Assessment Validation Study

Bringing Executive Function Testing Online: Assessment Validation Study

However, the timing varies considerably between the 2 tasks in that Freeze Frame utilizes a variable intertrial interval whereas SART has a consistent intertrial interval. The advantage of a variable time interval is that unlike consistent intertrial intervals, which increases attentional lapses and response anticipations [21], the unpredictable timing of the appearance of each image in Freeze Frame requires a more alert state and enhanced response control [22].

Mouna Attarha, Ana Carolina de Figueiredo Pelegrino, Lydia Ouellet, Sarah-Jane Grant, Etienne de Villers-Sidani, Thomas Van Vleet

JMIR Form Res 2025;9:e75687

The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial

The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial

One such study evaluated the effect of providing pregnant women with either 900 mg/day of a choline supplement or a placebo from week 17 of gestation through birth and found a beneficial effect of the choline supplement on 5-month-old infants’ auditory attentional gating [17].

Sophie A Roth, Angie E Lam, Barbara J Strupp, Richard L Canfield, Elisabeth Anne Larson

JMIR Res Protoc 2025;14:e73508