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Approach to Design and Evaluate Digital Tools to Enhance Young Adult Participation in Clinical Trials: Co-Design and Controlled Intercept Study

Approach to Design and Evaluate Digital Tools to Enhance Young Adult Participation in Clinical Trials: Co-Design and Controlled Intercept Study

While previous studies have examined the utility of mobile apps, social media, e-consenting tools, blockchain technology, web-based programs, and online messaging to improve clinical trial enrollment, few have specifically addressed the unique barriers faced by the young adult population. Yet, digital modalities have grown in popularity among this population for many indications including disease interventions and browsing emerging health information [13-15].

Tim Mackey, Raphael E Cuomo, Qing Xu, Tiana J McMann, Zhuoran Li, Mingxiang Cai, Christine Wenzel, Joshua S Yang

J Med Internet Res 2025;27:e70852

Effects of Using a Smart Bassinet on the Mental Health of Military-Affiliated Pregnant Women: Protocol for a Randomized Controlled Sleep Health and Mood in Newly Expectant Military Mothers (SHINE) Trial

Effects of Using a Smart Bassinet on the Mental Health of Military-Affiliated Pregnant Women: Protocol for a Randomized Controlled Sleep Health and Mood in Newly Expectant Military Mothers (SHINE) Trial

All web-based survey data will be published in accordance with the CHERRIES (Checklist for Reporting Results of Internet E-Surveys) checklist. To mitigate and minimize the possibility of missing data in the measures, we will program electronic questionnaires to prevent skipping questions. REDCap is a web application and back-end database model designed to support data capture for research studies.

Michele L Okun, Jennifer L Payne, Lauren M Osborne, Leilani Feliciano, Andrew Lac

JMIR Res Protoc 2025;14:e66439

Examining a Telemedicine-Based Virtual Reality Clinic in Treating Adults With Specific Phobia: Protocol for a Feasibility Randomized Controlled Efficacy Trial

Examining a Telemedicine-Based Virtual Reality Clinic in Treating Adults With Specific Phobia: Protocol for a Feasibility Randomized Controlled Efficacy Trial

After obtaining informed consent, supported by the REDCap e-Consent Framework feature, participants will be automatically directed to baseline questionnaire surveys, for which REDCap auto-calculates the scores. Following completion of the baseline assessment, the participant will be randomized to their respective treatment conduction using the Randomization Module.

Kaitlyn R Schuler, Triton Ong, Brandon M Welch, Jason G Craggs, Brian E Bunnell

JMIR Res Protoc 2025;14:e65770

Association of Social Media Recruitment and Depression Among Racially and Ethnically Diverse Metabolic and Bariatric Surgery Candidates: Prospective Cohort Study

Association of Social Media Recruitment and Depression Among Racially and Ethnically Diverse Metabolic and Bariatric Surgery Candidates: Prospective Cohort Study

A 2014 meta-analysis of 164 studies involving 160,000 patients found that BMI decreased by at least 11.8 kg/m² one-year post MBS, with sustained weight loss observed five years post surgery [5]. Most individuals who undergo MBS experience a reduction or complete elimination of obesity-related health issues, including high blood pressure, heart disease, diabetes, asthma, and osteoarthritis [6,7].

Jackson M Francis, Sitapriya S Neti, Dhatri Polavarapu, Folefac Atem, Luyu Xie, Olivia Kapera, Matthew S Mathew, Elisa Marroquin, Carrie McAdams, Jeffrey Schellinger, Sophia Ngenge, Sachin Kukreja, Benjamin E Schneider, Jaime P Almandoz, Sarah E Messiah

JMIR Form Res 2025;9:e58916