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The First 6 Years’ Experiences of a National Centralized Offspring Surveillance Setting for Dutch Children Prenatally Exposed to Maternal Cancer to Inform Future International Practice: Protocol for a Demographic Review of Referred Families and Key Lessons Learned

The First 6 Years’ Experiences of a National Centralized Offspring Surveillance Setting for Dutch Children Prenatally Exposed to Maternal Cancer to Inform Future International Practice: Protocol for a Demographic Review of Referred Families and Key Lessons Learned

Each visit includes a physical and neurological consultation by pediatric oncologists, a neuromotor assessment by a physiotherapist, and limited blood tests for children exposed to chemotherapy in utero (with consent). Cardiac screening is added in case of anthracycline exposure; and nephrological and audiological assessment, after platinum-based exposure.

Evangeline A Huis in 't Veld, Anouk M Kruse, Emma J Verwaaijen, Sterre C Huizer, Elisabeth M van Dijk-Lokkart, Christianne Lok, Maaike Kuethe, Frederic Amant, Mathilde M A van Gerwen, Martine van Grotel, Marry M van den Heuvel-Eibrink

JMIR Res Protoc 2025;14:e71612

Virtual Diabetes Prevention Program Tailored to Increase Participation of Black and Latino Men: Protocol for a Randomized Controlled Trial

Virtual Diabetes Prevention Program Tailored to Increase Participation of Black and Latino Men: Protocol for a Randomized Controlled Trial

The delivery of Power-Up includes a men-only, virtual, group-based model with men as coaches and an NDPP curriculum designed to be attentive to the concerns and needs of men. Virtual DPP is defined as a DPP program delivered remotely as synchronous classes through a videoconferencing platform. The intervention will be delivered virtually to participants recruited through clinical settings and available in English and Spanish.

Earle C Chambers, Elizabeth A Walker, Clyde Schechter, Eric Gil, Terysia Herbert, Katelyn Diaz, Jeffrey Gonzalez

JMIR Res Protoc 2025;14:e64405

A Customized Neural Transcranial Magnetic Stimulation Target for Functional Disability Among Veterans With Co-Occurring Alcohol Use Disorder and Mild Traumatic Brain Injury: Protocol for a Pilot Randomized Controlled Trial

A Customized Neural Transcranial Magnetic Stimulation Target for Functional Disability Among Veterans With Co-Occurring Alcohol Use Disorder and Mild Traumatic Brain Injury: Protocol for a Pilot Randomized Controlled Trial

If a participant refuses participation, no further contact will be made. If signed informed consent forms are completed, a note will be made in the Edward Hines Jr VA Hospital electronic medical record (EMR), and the original consent form will be kept in a locked cabinet in a locked research office behind swipe-access doors. Copies of the signed consent forms will be provided to the Edward Hines Jr VA Hospital IRB office. In addition, a copy will be provided to the participant.

Amy A Herrold, Alexandra L Aaronson, Dulal Bhaumik, Timothy Durazzo, Sherri L Livengood, Alma Ramic, Patrick Riordan, Neil Jordan, Todd Parrish, Trudy Mallinson, Ibuola O Kale, Andrea Billups, Kelly Krese, Sandra Kletzel, Noah S Philip, Theresa L Bender Pape

JMIR Res Protoc 2025;14:e64909

Acceptance-Based Pre-Exposure Prophylaxis Intervention (ACTPrEP) to Engage Young Black Men Who Have Sex With Men in the Southern United States: Protocol for a Pilot Randomized Controlled Trial

Acceptance-Based Pre-Exposure Prophylaxis Intervention (ACTPrEP) to Engage Young Black Men Who Have Sex With Men in the Southern United States: Protocol for a Pilot Randomized Controlled Trial

While there has been a 34% decrease in new HIV infections among young men who have sex with men, decreases are not equitable among ethnic groups [10]. Young Black men who have sex with men had a 27% decrease, while young White men who have sex with men had a 45% decrease [10].

Trisha Arnold, Kayla K Giorlando, Andrew P Barnett, Brandon A Gaudiano, Cara M Antonaccio, A Rani Elwy, Precious Patrick Edet, Lori M Ward, Laura Whiteley, Sarah Bailey, Brooke G Rogers, Avery Leigland, Jack C Rusley, Larry K Brown

JMIR Res Protoc 2025;14:e65921

Designing Clinical Decision Support Systems (CDSS)—A User-Centered Lens of the Design Characteristics, Challenges, and Implications: Systematic Review

Designing Clinical Decision Support Systems (CDSS)—A User-Centered Lens of the Design Characteristics, Challenges, and Implications: Systematic Review

If consensus was not reached, a third researcher (MV) was consulted for a resolution. Inclusion criteria Paper must be written in English. Paper must be published between 2013 and 2023 (last 10 years). All paper types are eligible, except reviews, systematic reviews, and books. Paper must be available in full text. Papers based on a designed Clinical Decision Support Systems (CDSS).

Andrew A Bayor, Jane Li, Ian A Yang, Marlien Varnfield

J Med Internet Res 2025;27:e63733

User Experiences With Digital Future-Self Interventions in the Contexts of Smoking and Physical Inactivity: Mixed Methods Multistudy Exploration

User Experiences With Digital Future-Self Interventions in the Contexts of Smoking and Physical Inactivity: Mixed Methods Multistudy Exploration

Relying on a single study risks offering a narrow or skewed viewpoint influenced by the specific FSI examined. Therefore, this multistudy paper triangulates behavioral, cognitive, and affective user experiences across several digital FSIs aimed at facilitating smoking cessation or PA promotion to offer a more comprehensive overview.

Kristell M Penfornis, Nele Albers, Willem-Paul Brinkman, Mark A Neerincx, Andrea WM Evers, Winifred A Gebhardt, Eline Meijer

JMIR Form Res 2025;9:e63893

Health Services Usage in Patients Receiving Buprenorphine for Opioid Use Disorder or Long-Term Opioid Therapy for Chronic Pain: Retrospective Cohort Study

Health Services Usage in Patients Receiving Buprenorphine for Opioid Use Disorder or Long-Term Opioid Therapy for Chronic Pain: Retrospective Cohort Study

SMI is also a common comorbidity for patients with OUD or chronic pain [28-30]. The purpose of including SMI as a comparison group was to descriptively assess whether the observed trends were specific to patients with buprenorphine for OUD or chronic opioid analgesic therapy. We evaluated the use of services and access to care from January 2018 to February 2022, using data from the Optum Labs Data Warehouse (OLDW), a deidentified, national, medical claims database [31].

Samuel T Savitz, Maria A Stevens, Bidisha Nath, Gail D'Onofrio, Edward R Melnick, Molly M Jeffery

JMIR Form Res 2025;9:e66596

Development of Machine Learning–Based Risk Prediction Models to Predict Rapid Weight Gain in Infants: Analysis of Seven Cohorts

Development of Machine Learning–Based Risk Prediction Models to Predict Rapid Weight Gain in Infants: Analysis of Seven Cohorts

Several systematic reviews concluded that rapid weight gain (RWG) from birth to the age of 1 year, defined as the upward centile crossing in a weight growth chart, was associated with a fourfold higher risk of later obesity than those without infant RWG [14,15]. As such, infant RWG is considered a sensitive proxy marker that denotes future obesity risk.

Miaobing Zheng, Yuxin Zhang, Rachel A Laws, Peter Vuillermin, Jodie Dodd, Li Ming Wen, Louise A Baur, Rachael Taylor, Rebecca Byrne, Anne-Louise Ponsonby, Kylie D Hesketh

JMIR Public Health Surveill 2025;11:e69220

Improving HIV Prevention Among Heterosexual Men Seeking Sexually Transmitted Infection Services in Malawi: Protocol for a Type I Effectiveness-Implementation Hybrid Randomized Controlled Trial of Systems Navigator–Delivered Integrated Prevention Package (HPTN 112-NJIRA Study)

Improving HIV Prevention Among Heterosexual Men Seeking Sexually Transmitted Infection Services in Malawi: Protocol for a Type I Effectiveness-Implementation Hybrid Randomized Controlled Trial of Systems Navigator–Delivered Integrated Prevention Package (HPTN 112-NJIRA Study)

Access to a systems navigator Intended to engage with participants at each preexposure prophylaxis (Pr EP) visit using a menu of “sessions” that examine items such as risk perception and address barriers to Pr EP adherence (Multimedia Appendix 1); provide reminders for upcoming Pr EP visits; and trace participants who have missed a scheduled Pr EP visit via phone or in person. 2.

Sarah E Rutstein, Laura Limarzi-Klyn, Jane S Chen, Yaw O Agyei, Shahnaz Ahmed, Ian Bell, Myron Cohen, Jessica M Fogel, Vivian Go, Dan Haines, Erica L Hamilton, Irving F Hoffman, Mina C Hosseinipour, Mark A Marzinke, William C Miller, Mathews Mukatipa, Julie Pulerwitz, Hans M L Spiegel, Ting Ye, Mitch Matoga

JMIR Res Protoc 2025;14:e72981

Evaluating Effectiveness of mHealth Apps for Older Adults With Diabetes: Meta-Analysis of Randomized Controlled Trials

Evaluating Effectiveness of mHealth Apps for Older Adults With Diabetes: Meta-Analysis of Randomized Controlled Trials

To our knowledge, there has not been a meta-analysis to evaluate the effectiveness of m Health apps for improving older diabetic adults’ health outcomes. The identified meta-analyses evaluated m Health apps on a wider age spectrum and do not evaluate the effectiveness for older adults [10,24-29], but see the study by Robert et al [30] for e Health nutrition intervention.

Renato Ferreira Leitao Azevedo, Michael Varzino, Erika Steinman, Wendy A Rogers

J Med Internet Res 2025;27:e65855