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Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

The primary end point is the change in the Fugl-Meyer Assessment (FMA) motor score from the start of treatment to 3 months later. Our secondary objectives are as follows: To compare the effects of botulinum toxin A and placebo on motor recovery (FMA) over 3 months and establish clinical equivalence. To evaluate the impact of treatment on motor recovery (main objective and placebo comparison) based on initial FMA-upper extremity (FMA-UE) scores.

Emmeline Montane, Nabila Brihmat, Camille Cormier, Claire Thalamas, Vanessa Rousseau, Gerard Tap, Xavier De Boissezon, Evelyne Castel-Lacanal, Baclotox Group, Philippe Marque

JMIR Res Protoc 2025;14:e62951

Evaluating a Web-Based Application to Facilitate Family-School-Health Care Collaboration for Children With Neurodevelopmental Disorders in Inclusive Settings: Protocol for a Nonrandomized Trial

Evaluating a Web-Based Application to Facilitate Family-School-Health Care Collaboration for Children With Neurodevelopmental Disorders in Inclusive Settings: Protocol for a Nonrandomized Trial

Meyer et al [35] identified 6 digital projects and a strategy using an existing social network, all at different development stages. Of these projects, 3 used participatory design, 4 conducted needs analyses, and 3 were field-tested. However, none included a control group nor aimed to evaluate the impact on school inclusion, IEPs, stakeholder interactions, or health and well-being dimensions.

Eric Meyer, Hélène Sauzéon, Isabeau Saint-Supery, Cecile Mazon

JMIR Res Protoc 2025;14:e63378