TY  - JOUR
AU  - Arquembourg, Jocelyne
AU  - Glaser, Philippe
AU  - Roblot, France
AU  - Metzler, Isabelle
AU  - Gallant-Dewavrin, Mélanie
AU  - Nanguem, Hugues Feutze
AU  - Mebarki, Adel
AU  - Voillot, Paméla
AU  - Schück, Stéphane
PY  - 2025
DA  - 2025/4/25
TI  - Discussions of Antibiotic Resistance on Social Media Platforms: Text Mining and Mixed Methods Content Analysis Study
JO  - JMIR Form Res
SP  - e37160
VL  - 9
KW  - antibiotic ineffectiveness
KW  - antibiotic resistance
KW  - health-related quality of life
KW  - real-world
KW  - social media
KW  - quality of life
KW  - quantitative
KW  - qualitative
KW  - app
KW  - application
KW  - online
KW  - medical information
KW  - French
KW  - users
KW  - antibiotic
KW  - social media use
AB  - Background: With the increasing popularity of web 2.0 apps, social media has made it possible for individuals to post messages on antibiotic ineffectiveness. In such online conversations, patients discuss their quality of life (QoL). Social media have become key tools for finding and disseminating medical information. Objective: To identify the main themes of discussion, the difficulties encountered by patients with respect to antibiotic ineffectiveness and the impact on their QoL (physical, psychological, social, or financial). Methods: A noninterventional retrospective study was carried out by collecting social media posts in French language written by internet users mentioning their experience with antibiotics, and the impact of their ineffectiveness on their QoL. Messages posted between January 2014 and July 2020 were extracted from French-speaking publicly available online forums. Results: A total of 3773 messages were included in the analysis corpus after extraction and filtering. These messages were posted by 2335 individual web users, most of them being women around 35 years of age. Inefficacy of treatment options and the lack of information regarding the use of antibiotics were among the most discussed topics. QoL was discussed in 63% of the 3773 messages posted. The most common is the physical impact (78%). Patients discussed the persistence of symptoms and adverse effects. The second kind of impact is psychological (65%), characterized by feelings of anxiety or despair about the situation. Conclusions: This social media analysis allowed us to identify a strong impact of the perceived ineffectiveness of antibiotic therapy on patients’ daily life particularly in terms of physical and psychological consequences. These results provide health care experts information directly generated by patients regarding their own experiences. Social media studies constitute a complementary source of evidence that could be used to optimize messages to the public about appropriate use of antibiotics. 
SN  - 2561-326X
UR  - https://formative.jmir.org/2025/1/e37160
UR  - https://doi.org/10.2196/37160
DO  - 10.2196/37160
ID  - info:doi/10.2196/37160
ER  -