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Innovating Care for Postmenopausal Women Using a Digital Approach for Pelvic Floor Dysfunctions: Prospective Longitudinal Cohort Study

Innovating Care for Postmenopausal Women Using a Digital Approach for Pelvic Floor Dysfunctions: Prospective Longitudinal Cohort Study

Statistical significance was defined as P Of the 3684 participants screened for eligibility, 633 participants were excluded (346 declined participation and 287 did not meet eligibility criteria; Figure 2). The program started with 3051 participants, of which 2367 participants completed it, translating into a completion rate of 77.6%. Study flowchart.

Ana P Pereira, Dora Janela, Anabela C Areias, Maria Molinos, Xin Tong, Virgílio Bento, Vijay Yanamadala, Jennesa Atherton, Fernando Dias Correia, Fabíola Costa

JMIR Mhealth Uhealth 2025;13:e68242

Evaluation of the Tu’Washindi Na PrEP Intervention to Reduce Gender-Based Violence and Increase Preexposure Prophylaxis Uptake and Adherence Among Kenyan Adolescent Girls and Young Women: Protocol for a Cluster Randomized Controlled Trial

Evaluation of the Tu’Washindi Na PrEP Intervention to Reduce Gender-Based Violence and Increase Preexposure Prophylaxis Uptake and Adherence Among Kenyan Adolescent Girls and Young Women: Protocol for a Cluster Randomized Controlled Trial

Pr EP uptake and adherence were both approximately twice as high in the intervention arm as in the control arm (P Because our pilot findings suggested that Tu’Washindi shows promise as an acceptable intervention that can be implemented with fidelity to promote Pr EP uptake and adherence among adolescent girls and young women without concomitant increases in IPV, we designed a fully powered effectiveness trial to determine whether these gains translate to increases in biomarker measures of Pr EP adherence and whether

Sarah T Roberts, Alexandra M Minnis, Sue Napierala, Elizabeth T Montgomery, Lina Digolo, Mackenzie L Cottrell, Erica N Browne, Jacqueline Ndirangu, Joyce Boke, Kawango Agot

JMIR Res Protoc 2025;14:e55931

Accelerometry-Assessed Physical Activity and Circadian Rhythm to Detect Clinical Disability Status in Multiple Sclerosis: Cross-Sectional Study

Accelerometry-Assessed Physical Activity and Circadian Rhythm to Detect Clinical Disability Status in Multiple Sclerosis: Cross-Sectional Study

The 2-sample t test P values show the 2-hour intervals when TAC was significantly different between the 2 groups. As an additional reference, the logistic regression P values are shown with the TAC 2-hour intervals used as predictors, after adjusting for age, sex, and BMI. MS: multiple sclerosis; PMS: progressive multiple sclerosis; RRMS: relapsing-remitting multiple sclerosis.

Nicole Bou Rjeily, Muraleetharan Sanjayan, Pratim Guha Niyogi, Blake E Dewey, Alexandra Zambriczki Lee, Christy Hulett, Gabriella Dagher, Chen Hu, Rafal D Mazur, Elena M Kenney, Erin Brennan, Anna DuVal, Peter A Calabresi, Vadim Zipunnikov, Kathryn C Fitzgerald, Ellen M Mowry

JMIR Mhealth Uhealth 2025;13:e57599

Automatic Human Embryo Volume Measurement in First Trimester Ultrasound From the Rotterdam Periconception Cohort: Quantitative and Qualitative Evaluation of Artificial Intelligence

Automatic Human Embryo Volume Measurement in First Trimester Ultrasound From the Rotterdam Periconception Cohort: Quantitative and Qualitative Evaluation of Artificial Intelligence

P values for the chi-square test are given. a EV: embryonic volume. b Not applicable. c GA: gestational age. d HV: head volume. For the HV, a total of 475 ultrasound scans of 326 participants were included. The data were divided over similar subsets. The development set contained 383 ultrasound scans of 261 participants acquired before 2020. The test set contained 92 ultrasound scans of 65 participants acquired before 2020. The future test set contained 80 ultrasound scans of 58 participants acquired in 2020.

Wietske A P Bastiaansen, Stefan Klein, Batoul Hojeij, Eleonora Rubini, Anton H J Koning, Wiro Niessen, Régine P M Steegers-Theunissen, Melek Rousian

J Med Internet Res 2025;27:e60887