Original Paper
Abstract
Background: Black women experience dual disparities with disproportionately high rates of HIV infection and low uptake of preexposure prophylaxis (PrEP). To address this issue, a culturally relevant eHealth video intervention was developed to increase awareness and uptake of PrEP.
Objective: This study aims to evaluate the usability, acceptability, and impact of a culturally tailored eHealth video intervention (“Put Yourself First”) on PrEP-related knowledge and motivation among young Black women.
Methods: This study used a sequential, mixed methods design. Thirteen young, primarily heterosexual, Black women, aged 18-25 years, were recruited from community-based organizations and social networks in New York City to participate in 2 evaluation focus groups. Participants completed pre- and postvideo assessments, followed by facilitated focus group discussions to elicit qualitative feedback on the video’s usability, acceptability, and impact on PrEP knowledge.
Results: After watching the eHealth video, knowledge scores increased significantly postviewing (P=.04). Most participants indicated willingness to consider PrEP (10/13, 77%), and all reported intentions to recommend it to others (13/13, 100%). Overall, 92% (12/13) of the participants rated the video as very good or excellent. Participants found the video to be very interesting (11/13, 85%) and useful (12/13, 92%). The qualitative findings suggest that representation, authenticity, and the normalization of PrEP use emerged as critical drivers of acceptability. It also highlighted the video’s relatability, cultural relevance, and ability to dispel misconceptions, while also identifying areas for refinement for future studies.
Conclusions: Findings support the acceptability and usability of culturally tailored sex-positive eHealth interventions for improving PrEP awareness and motivation among young Black women. Culturally resonant multimedia centering the voices of young Black women to affirming pleasure, agency, and addressing structural barriers to engagement offers a promising strategy for HIV prevention.
doi:10.2196/74132
Keywords
Introduction
Despite Black women’s vulnerability to HIV transmission and the availability of preexposure prophylaxis (PrEP) in the United States, many Black women continue to lack essential information about its benefits and accessibility [,]. According to the Centers for Disease Control and Prevention (CDC), only a small percentage of eligible Black women were aware of PrEP, and even fewer were using it [-]. Cultural and structural factors, such as inadequate representation in PrEP advertising and provider discomfort discussing HIV prevention options with Black women, further hinder PrEP adoption []. Addressing these challenges requires culturally relevant messaging and targeted outreach to reduce multilevel barriers, such as limited functional knowledge of PrEP, low perceived susceptibility to HIV transmission, medical mistrust, stigma, and constrained health care access [,-]. These efforts must also be aligned with empowering Black women to make informed decisions about their sexual health practices, including HIV prevention [].
Research suggests that animated educational videos can be practical tools for improving health knowledge and health literacy across diverse populations [-]. These videos are generally well-received by participants and can raise awareness, facilitate engagement, and reduce anxiety [-]. Video-based interventions have been shown to increase not only knowledge but also comprehension, which reduces uncertainty in decision-making and improves patient outcomes compared to written material [-]. Multimedia formats, such as animation [], and delivery channels, including mobile video messaging, have enhanced PrEP knowledge and increased comfort discussing PrEP with providers [].
In the context of HIV prevention, video interventions have shown promise in increasing knowledge, awareness, and intentions to use PrEP among various populations, including Black women [,]. However, most video-based HIV prevention tools have been developed for men who have sex with men or broad, mixed-gender audiences. Black women’s prevention needs are shaped by gendered racism, relationship dynamics, and systemic health care inequities [,,]; yet, few video-based HIV interventions have been explicitly designed for them related to PrEP [,]. Current eHealth interventions also tend to focus narrowly on nominal awareness, while neglecting relational and structural barriers, such as provider bias, partner mistrust, and burdensome medical monitoring that disproportionately shape Black women’s PrEP decisions [,]. A recent longitudinal study with young Black women also highlights that barriers to PrEP initiation change over time, emphasizing the need for ongoing support and integrated, culturally tailored PrEP education for women’s sexual health care []. Most HIV prevention messaging tends to focus on risk framing, while sex-positive narratives that affirm pleasure, intimacy, and autonomy are largely absent when directed toward women []. This common practice leaves a critical gap in approaches, perpetuates invisibility, and disengagement in HIV prevention efforts that could resonate more powerfully with the intersectional dynamics of Black women’s lived experiences [].
The literature suggests that eHealth interventions, particularly video-based educational tools, can effectively increase awareness and knowledge about PrEP among Black women []. By addressing the current gaps in understanding and using engaging multimedia formats, there is potential to overcome barriers to accessing PrEP and ultimately improve health outcomes in this underserved population. The purpose of this study is 2-fold: (1) to evaluate the usability, acceptability, and impact of a culturally tailored eHealth video intervention (“Put Yourself First”) on PrEP-related knowledge and motivation among young Black women, and (2) to gather participant feedback to inform future refinements to its content and delivery. By directly addressing misconceptions, providing evidence-based information, and promoting open communication between providers and patients, this video aims to empower Black women to make informed decisions about their sexual health. Notably, the intervention uses culturally authentic narratives that are grounded in a sex-positive framework [], positioning PrEP not only as an HIV prevention tool but also as a means of supporting autonomy, intimacy, and pleasure as integral aspects of women’s sexual well-being. This study was grounded in multiple theoretical frameworks that informed both the development and evaluation of the intervention. Specifically, intersectionality [,], Black Feminist Thought (BFT) [], and the Theory of Triadic Influence (TTI) [] helped identify multilevel barriers to PrEP uptake among young Black women, while the Information-Motivation-Behavioral Skills (IMB) model [] guided mapping behavioral determinants of PrEP use. In addition, the education-entertainment (edutainment) framework [,] guided the translation of these theoretical insights into culturally tailored, sex-positive, and engaging video content. Collectively, these frameworks informed the design of a culturally tailored, sex-positive, action-oriented video intervention aimed at improving PrEP awareness and uptake.
Methods
Study Design Overview
The LOVE (Learning Options through Video Education) study is a sequential, mixed methods pilot study designed to explore factors influencing Black women’s interest in oral PrEP and to assess the feasibility of a brief, culturally tailored eHealth intervention aimed at increasing PrEP awareness and motivation. depicts the study’s phased approach to developing and evaluating an innovative intervention. The four phases included (1) conducting exploratory focus groups to identify barriers and facilitators to PrEP uptake; (2) intervention mapping []; (3) development of the 5-minute, 3-part animated video, “Put Yourself First”; and (4) evaluation focus groups to assess the video’s usability, acceptability, and impact on PrEP knowledge. Detailed procedures for Phases 1, 2, and 3, including the literature review process and leadership of the intervention mapping activities, will be reported in a separate manuscript. This paper focuses exclusively on Phase 4, which evaluated the “Put Yourself First” video intervention.

Study Sample
Women were recruited from community-based organizations and through social networking sites in New York City. The study recruited heterosexual Black women residing in New York City. The study prioritized this population due to the city’s disproportionately high HIV prevalence among Black women and the persistent gaps in PrEP awareness and uptake documented in prior research []. A member of the research team screened the women based on the following criteria: (1) aged 18 to 25 years; (2) self-identified as heterosexual; (3) self-identified as African American, Black, Caribbean Black, or multiethnic Black; (4) self-reported HIV-negative or with unknown HIV status; (5) reported oral, vaginal, or anal sex with a man in the past 12 months; (6) current or past problematic substance use; and (7) residency in New York City. We screened 78 women, of whom 37 (47%) were eligible and 26 (33%) consented to participate in the study. Reasons for nonparticipation after screening were not systematically collected. No nonparticipants (eg, observers or organizational staff) were present during the focus groups aside from the cofacilitators. Thirteen women from the final sample participated in the explanatory focus group discussions.
Procedures
Study visits were conducted in English by trained research staff in a private space. The evaluation focus groups were co-led by the first author (a qualitative researcher with doctoral training in public health and extensive experience conducting focus groups with Black women) and a trained research assistant. Both facilitators were identified as Black women, which may have enhanced rapport and comfort among participants. Neither facilitator had prior personal relationships with participants. During recruitment and consent, participants were informed that the purpose of the groups was to gather honest feedback about the “Put Yourself First” video, and facilitators emphasized that there were no right or wrong answers. After rescreening for eligibility, participants underwent a detailed verbal informed consent process prior to data collection commencing. Eligible women were invited to participate in a Brief Assessment Battery (BAB) survey administered by tablet or paper and a focus group. The BAB validated measures to assess women’s initial knowledge of PrEP [], HIV knowledge [], sexual behaviors, relationship dynamics [], self-efficacy [], and HIV stigma []. During Phase 4, participants were recruited to participate in explanatory focus groups to evaluate the video’s effectiveness through 2 focus groups (Group 3: n=7; Group 4: n=6). The first part of the explanatory focus group examined the factors that impede and facilitate PrEP use []. Participants were shown the 5-minute educational video, “Put Yourself First” ().

A still image from the eHealth intervention’s animated video shows 3 Black women characters engaging in a casual conversation at a café, introducing the topic of PrEP. The central character gestures while discussing PrEP, with the acronym prominently displayed in large white letters and the full term, Preexposure Prophylaxis, in pink text below. This visual design situates PrEP education within a relatable, everyday social setting, reflecting the intervention’s culturally tailored, peer-to-peer communication approach to normalize PrEP discussions among Black women.
After viewing the video, participants completed a postvideo survey to assess the acceptability, perceived impact, and effects on knowledge and intentions. The second part of the explanatory focus groups was conducted to elicit feedback on the video’s usability, structure, and appeal. The focus group guide included questions not only about the video’s content (accuracy, clarity of PrEP information, cultural resonance, and stigma reduction) but also about its format, style, and representation (eg, use of animation, relatability of characters, and overall usability and appeal). The guide ensured that participant feedback addressed both informational and stylistic components of the video. This article is centered on the section of the focus group discussion that addressed the video’s usability, structure, and appeal. The audio-recorded focus groups took approximately 2 hours to complete. Although field notes were not taken, audio recordings were transcribed verbatim to ensure accuracy. This paper was prepared in accordance with the COREQ (Consolidated Criteria for Reporting Qualitative Research) checklist to enhance transparency and rigor in reporting qualitative methods and findings [].
Postvideo Survey
The postvideo survey was administered immediately after participants watched the animated PrEP video (“Put Yourself First”). The postvideo survey comprises five parts: (1) PrEP knowledge (10 items, “True,” “False,” and “Don't know”) covering core facts such as HIV-negative eligibility, 3-month HIV testing while on PrEP, typical side effects, condom recommendations, distinction from postexposure prophylaxis, and hepatitis B virus considerations; (2) concerns about PrEP (13 items, “Yes,” “No,” and “Don’t know”) assessing safety (long-term and reproductive), side effects, resistance, perceived incomplete protection, daily pill burden, potential risk compensation (self and partners), stigma and privacy, comfort discussing sex with providers, and cost; (3) conditions for uptake (8 items, “Yes,” “No,” and “Don’t know”) eliciting enabling factors such as no-cost access, free HIV testing and monitoring, one-on-one or text-based counseling, group adherence support, and nonclinic access points; (4) acceptability, intentions, and global rating including willingness to recommend the video (Yes or No), a 1-6 overall quality rating, and intentions to consider or recommend PrEP; and (5) narrative engagement and perceived impact plus a brief global appraisal (5-point items) capturing story realism, message salience, character identification and liking, perceived social diffusion, and the likelihood of behaviors such as asking a provider about PrEP, requesting condom use, resisting unwanted sex, and obtaining HIV testing, alongside ratings of interest, usefulness, amount learned, comprehension, and liking.
Data Analysis
Descriptive statistics from the surveys were calculated for the participants using IBM SPSS Statistics for Windows, version 29.0.2.0 [], to summarize the data, including sociodemographic characteristics, sexual behavior, PrEP knowledge, and video acceptability. Pre- and posttest scores for PrEP knowledge were compared using paired-sample t tests for the full sample and within each group. Statistical significance was defined as P≤.05.
Audiotapes of the focus group discussions were transcribed. The transcripts were imported into Dedoose (SocioCultural Research Consultants, LLC) [] software for coding and analysis. The research team analyzed the transcripts, but they were not returned to the participants for comment. Similarly, participants did not engage in formal member checking of findings, which we note as a methodological limitation. Two lead analysts and a research assistant, trained in qualitative methods, identified codes and used a multilayered strategy based on the topics addressed in the focus group guide. Analysis occurred in multiple stages, corresponding to the inductive approaches of open coding and axial coding used in grounded theory [,]. Codes were compared, refined, and reorganized through consensus discussions. To assess the breadth of issues raised, themes from the first focus group were compared to those from the second. While the small sample size precluded claims of definitive saturation, no substantially new themes emerged in the second group beyond those identified in the first. This consistency suggested adequate coverage of core issues for the scope of this exploratory evaluation [,]. Thus, we characterize our findings as reflecting preliminary thematic coverage rather than full saturation, consistent with grounded theory approaches in small-sample qualitative studies []. Here, we report evaluation findings from the 2 explanatory focus groups that assessed the eHealth video’s effectiveness and acceptability for increasing knowledge and addressing barriers to PrEP uptake among young Black women. All analysts worked independently to identify codes, ensuring that themes were consistently represented in the data.
Ethical Considerations
This study was reviewed and approved by the New York University Institutional Review Board (approval number IRB-FY2017-408). All participants provided written informed consent prior to participation. Participants who completed the focus groups received US $45 in compensation and a 2-fare New York City Metrocard. To protect participant privacy and confidentiality, all data were deidentified, stored in a secure location, and securely transferred electronically to investigators involved in the analysis.
Results
Sample Description
presents the sociodemographic characteristics of the participants in the explanatory focus group (N=13). Participants had a mean age of 22 (SD 2.4) years, and the majority were US-born (11/13, 85%). Over half (7/13, 54%) had completed high school or a General Education Diploma, while 38% (5/13) had some college or trade school education, and 8% 1/13) held a college degree; 38% (5/13) were current students. Most participants were unemployed (6/13, 46%) or worked part-time (5/39, 39%), with the majority (10/13, 77%) reporting an annual income of less than US $19,999. All participants had health insurance, and 62% (8/13) had a primary care provider.
| Characteristics | Participants | |
| Age (years), mean (SD) | 22 (2.4) | |
| US-born, n (%) | ||
| Yes | 11 (85) | |
| Education, n (%) | ||
| High school or GEDa | 7 (54) | |
| Some college or trade school | 5 (38) | |
| College degree | 1 (8) | |
| Current student, n (%) | ||
| Yes | 5 (38) | |
| Employment, n (%) | ||
| Full-time | 2 (15) | |
| Part-time | 5 (39) | |
| Unemployed | 6 (46) | |
| Annual income, n (%) | ||
| Less than US $19,999 | 10 (77) | |
| More than US $40,000 | 3 (23) | |
| Health insurance, n (%) | ||
| Yes | 13 (100) | |
| Primary care provider, n (%) | ||
| Yes | 8 (62) | |
| Has children, n (%) | ||
| Yes | 3 (23) | |
| Relationship status, n (%) | ||
| Committed relationship | 4 (31) | |
| Dating | 8 (62) | |
| Single | 1 (8) | |
| Current HIV test (past year), n (%) | ||
| Yes | 9 (69) | |
| Positive STIb results (lifetime), n (%) | ||
| Yes | 7 (54) | |
| Have main or steady partner, n (%) | ||
| Yes | 13 (100) | |
| Have sex with nonmain partners, n (%) | ||
| Yes | 5 (39) | |
| Main or steady partner has sex with other, n (%) | ||
| Yes | 5 (39) | |
| Did not use condom, 3 months, n (%) | ||
| Main or steady partner | 12 (92) | |
| Other partner (n=5) | 3 (60) | |
| Knowledge of PrEPc, n (%) | ||
| Yes | 10 (77) | |
| Used PrEP, n (%) | ||
| Yes | 2 (15) | |
| Knowledge of PEPd, n (%) | ||
| Yes | 8 (62) | |
| Used PEP, n (%) | ||
| No | 13 (100) | |
aGED: General Education Diploma.
bSTI: sexually transmitted infection.
cPrEP: preexposure prophylaxis.
dPEP: postexposure prophylaxis.
Regarding family and relationships, 23% of participants (3/13) had children, and most (8/13, 62%) reported being in a dating relationship, while 31% (4/13) were in a committed relationship. All participants reported having a primary or steady partner, and 39% (5/13) also engaged in sex with nonmain partners; notably, 39% (5/13) indicated their steady partner had other sexual partners. Condomless sex with steady partners was nearly universal (12/13, 92%) and occurred with 60% (3/5) of nonmain partners. Concerning HIV prevention, 69% (9/13) tested for HIV within the past year, and over half (7/13, 54%) reported having a sexually transmitted infection (STI) at some point in their life. While most participants knew about PrEP (10/13, 77%), only 2 (15%) had ever used it. Awareness of postexposure prophylaxis was lower (8/13, 62%), with no reported use.
Pre- and Posttest of PrEP Knowledge
presents the pre- and posttest knowledge scores for the participants by group and collectively. Across all participants (N=13), mean scores increased significantly from 4.6 (SD 2.9) at pretest to 6.5 (SD 1.8) at posttest, for a mean difference of –1.9 points (95% CI –3.7 to –0.14; t12=–2.3; P=.04). Group-level analyses indicated significant gains among Group 3 participants (n=7), whose mean scores improved from 4.2 (SD 2.9) to 6.3 (SD 2.1), a mean difference of –2.0 points (95% CI –3.3 to –0.69; t6= –3.7; P=.01). Group 4 (n=6) demonstrated improvement as well, with mean scores rising from 5.0 (SD 3.1) to 6.8 (SD 1.5), though the change was not statistically significant (mean difference –1.8; 95% CI –6.4 to 2.7; t5= –1.04; ns).
| Group | N | Pretest, mean (SD) | Posttest, mean (SD) | Mean difference | 95% CI | t test (df) | P value |
| Both | 13 | 4.6 (2.9) | 6.5 (1.8) | –1.9 | (–3.7 to –0.14) | –2.3 (12) | .04 |
| Group 3 | 7 | 4.2 (2.9) | 6.3 (2.1) | –2.0 | (–3.3 to –0.69) | –3.7 (6) | .01 |
| Group 4 | 6 | 5.0 (3.1) | 6.8 (1.5) | –1.8 | (–6.4 to 2.7) | –1.04 (5) | nsb |
aPrEP: preexposure prophylaxis.
bns: not significant.
Barriers and Facilitators to PrEP Uptake
presents the key barriers and facilitators to PrEP uptake. Barriers to PrEP included concerns about side effects and stigma related to others noticing medication use, each reported by 62% (8/13) of participants, as well as concerns about reproductive health (7/13, 54%). Participants reported cost, daily pill burden, and partner expectations less frequently. Notably, no participants expressed discomfort about discussing sexual health with a provider. In contrast, strong facilitators were identified, particularly access to text-based support (12/13, 92%), counseling about sex and relationships (11/13, 85%), and free HIV testing, monitoring, and one-on-one counseling (10/13, 77%). More than half also reported that free medication (8/13, 62%) and group-based adherence support (7/13, 54%) would enable uptake.
| Item | Participants | |
| Barriers, n (%) | ||
| I am worried about the long-term effects of PrEP on my overall health. | 6 (46) | |
| I am worried about the long-term effects of PrEP on my reproductive health. | 7 (54) | |
| I am worried about the side effects. | 8 (62) | |
| I am worried that if I do become HIV positive, certain medicines won’t work because I was taking PrEP. | 2 (15) | |
| I am worried that PrEP does not provide complete protection against HIV. | 5 (39) | |
| I am worried about having to take a pill every day. | 2 (15) | |
| I am worried that taking PrEP might make me more likely to have sex without a condom. | 4 (31) | |
| I am worried that having to take PrEP means I am putting myself at risk for HIV. | 3 (23) | |
| I am worried that PrEP might make my partner(s) expect me to have sex without a condom. | 1 (8) | |
| I am worried that people will see me taking medication and think I have HIV. | 2 (15) | |
| I am worried that people will see me taking medication and will want to know why I am taking it. | 8 (62) | |
| I am worried about having to talk to my doctor about my sex life. | 0 | |
| PrEP is too costly. | 2 (15) | |
| Facilitators (I would take PrEP, if...), n (%) | ||
| I did not have to pay for PrEP. | 8 (62) | |
| I had access to free HIV testing. | 10 (77) | |
| I had access to free sexual health and monitoring while on PrEP. | 10 (77) | |
| I had one-on-one counseling and support around PrEP use. | 10 (77) | |
| I had access to text-based support for PrEP use. | 12 (92) | |
| I had access to support or counseling about my sex life. | 11 (85) | |
| I did not have to go to my regular doctor to get PrEP. | 4 (31) | |
| I had access to group-based adherence support for PrEP use. | 7 (54) | |
aPrEP: preexposure prophylaxis.
Video Acceptability and Perceived Impact
presents findings on postviewing acceptability and intentions related to the PrEP video intervention. Most participants (10/13, 77%) reported they would consider using PrEP, and all (13/13, 100%) stated they would recommend it to others. The majority rated the video’s quality as very good (9/13, 69%) or excellent (3/13, 23%), and nearly all found it very or extremely interesting (11/13, 85%) and useful (12/13, 92%). Overall, 62% (8/13) reported learning a great deal of new information, while 92% (12/13) indicated they understood the content very well and liked the video very much.
| Item | Participants | ||
| Intention to consider PrEPa, n (%) | |||
| Yes | 10 (77) | ||
| Intention to recommend PrEP to others, n (%) | 13 (100) | ||
| Overall video quality rating, n (%) | |||
| Very good | 9 (69) | ||
| Excellent | 3 (23) | ||
| How interesting was the video, n (%) | |||
| Very interesting | 5 (39) | ||
| Extremely interesting | 6 (46) | ||
| How useful was the video, n (%) | |||
| Very useful | 6 (46) | ||
| Extremely useful | 6 (46) | ||
| Amount of new information learned from video, n (%) | |||
| None | 2 (15) | ||
| Little | 1 (8) | ||
| Some | 2 (15) | ||
| A great deal | 8 (62) | ||
| How much did you understand in this video, n (%) | |||
| Very much | 12 (92) | ||
| How much did you like the video, n (%) | |||
| Very much | 12 (92) | ||
aPrEP: preexposure prophylaxis.
presents data on narrative engagement and the perceived impact of the PrEP video. Most participants found the storyline credible (9/13, 69%) and agreed that the message raised awareness (10/10, 77%) and supported action (8/13, 62%). Overall, 62% (8/13) reported relating to some characters and 31% (4/13) to most or all of them. The main character was universally well-received, with all participants describing her as likable, relatable, and compelling at emphasizing key messages. In terms of behavioral intentions, participants expressed a high likelihood of obtaining HIV testing (11/13, 85%) and asking a provider about PrEP (10/13, 77%), with a moderate likelihood of recommending PrEP (8/13, 62%), requesting condom use (7/13, 54%), and resisting condomless or unwanted sex (6/13, 46%).
| Item | Participants | |
| Story realism or credibility, n (%) | ||
| Definitely Yes | 9 (69) | |
| Message raises awareness, n (%) | ||
| Definitely Yes | 10 (77) | |
| Message supports action, n (%) | ||
| Definitely Yes | 8 (62) | |
| Identification with characters, n (%) | ||
| I could relate to some of the characters. | 8 (62) | |
| I could relate to many of the characters. | 1 (8) | |
| I definitely related to most or all the characters. | 4 (31) | |
| Main character, n (%) | ||
| Likeability | 13 (100) | |
| Type of friend you like to talk to | 13 (100) | |
| Emphasize important messages | 13 (100) | |
| Add to experience of learning about PrEPa | 11 (85) | |
| Likelihood, n (%) | ||
| Ask a provider about PrEP | 10 (77) | |
| Recommend PrEP to someone | 8 (62) | |
| Request condom use | 7 (54) | |
| Change attitude about having unwanted sex | 6 (46) | |
| Resist condomless sex | 6 (46) | |
| Obtain HIV testing | 11(85) | |
aPrEP: preexposure prophylaxis.
Feedback From Explanatory Focus Groups
The qualitative findings identified 6 areas of focus: viewers’ engagement and perceived impact, relatability through authentic representation, navigating relationships while prioritizing personal health, structural and practical barriers to PrEP adherence, empowerment through health autonomy, and domains requiring further development.
Viewers’ Engagement and Perceived Impact
Participants found the video engaging and informative, describing it as “cute” and compelling in its provision of critical information about PrEP. The participant said, “It’s a nice way to get information out.” For some participants, the video served as a valuable educational tool by introducing new information about PrEP’s availability for women. As 1 participant noted, “It gives you more of that knowledge and info, so you understand it a little bit more.” The video successfully addressed the misconception that PrEP is only for gay men, reinforcing its relevance for women. They appreciated how it addressed and clarified misconceptions, such as the belief that PrEP is only for gay men. As 1 participant shared, “It helps with the message because the main person that was talking was a Black lady and she was just basically letting them know it's not only for gay people and you know, whatever the case may be. And it's good for women to take it because it helps as an addition to the condoms, you know.” Many participants described the video’s message as powerful and informative, providing a better understanding of PrEP’s purpose and its role in preventing HIV. Participants valued the emphasis on PrEP being a personal choice, with one saying, “powerful message,” and another adding, “It gives you more of that knowledge and info so you understand it a little bit more.”
Relatability Through Authenticity
Participants found several scenarios in the video particularly relatable to their own experiences. Many appreciated the conversational style, noting the realistic portrayal of 3 friends casually discussing PrEP over coffee, mirroring how “home girls” would talk among themselves, which added credibility to the message. One participant stated, “It was just a conversation between 3 home girls. I say home girls having coffee or whatever. You know it wasn't. Well, of course, it's scripted, but it didn't feel scripted. It felt like you were just watching like three characters having a normal conversation.” Another participant noted that the friends’ reactions to PrEP in the video reflected how she expected her peers to respond, with some being receptive and others skeptical. “I feel like that's how my friends would react, the way her friends were reacting. You know you're trying to tell people things to help them, especially your friends, but everybody has their own opinion and everybody [does] things on their own time.” Participants emphasize how the characters engaged in a mutual exchange of information about PrEP, making the learning process feel organic and authentic. As 1 participant highlighted the collaborative and peer-driven learning aspect of the video, “The good thing was that all three of them [were] sharing information about PrEP to each other. They were actually learning from each other.”
Navigating Relationships While Prioritizing Personal Health
Many participants resonated with the challenge of balancing personal health decisions with concerns about how a partner might perceive PrEP use, including fears of mistrust or judgment. A discussion centered around how introducing PrEP might raise questions in a relationship: “It probably would raise questions, but at the same time, then it's like, you know, why are you taking this all of a sudden?” A recurring theme in the discussion was relationship dynamics and the tendency for Black women to put others’ needs before their own, particularly in relationships, making it difficult to prioritize personal health. The scenario where a character contemplates her partner’s response to her using PrEP resonated deeply, reflecting common experiences among participants. One participant highlighted this dynamic, stating, “One of the characters was like, 'What about what he thinks,' and she was like, 'That's the problem with Black women. They always put people first before themselves.' I closely identify with that, but I never really thought about it. I think that's one of our biggest traits.” Another participant echoed this sentiment, emphasizing the tendency to prioritize a partner’s feelings over personal health: “She's not thinking about herself first. She's thinking about what he's going to think.” Concerns about a partner’s perception of PrEP use also emerged, as one participant explained, “I would say letting her partner know. I mean, like, to be honest, for some women, they would feel some type of way because you're taking something to prevent them, so probably the man that she's with is going to feel like she's doing something.”
Structural and Practical Barriers to PrEP Adherence
Participants found the video’s depiction of a character’s reluctance to adhere to the medical visits required for PrEP highly relatable and honest. Many agreed that frequent doctor visits pose a structural barrier to adherence, as women often juggle multiple responsibilities, making it difficult to schedule regular health care appointments. To improve accessibility, some participants suggested including alternative options, such as home testing, in the messaging. One participant emphasized this point, stating, “The biggest issue is the inconvenience of having to go to the doctor. A home test would make a big difference. Along with your prescription, you get a home test.” The video also ignited a discussion on the varied perspectives surrounding adherence and health care engagement. While some participants expressed a strong sense of personal responsibility in maintaining their health, others highlighted the challenges of staying consistent with medical visits. One participant explained, “I say it could, but it depends on who you are. Some people like to keep up with themselves. Like me, I'm that type of person. Like, I don't want anything to happen to me. I'm overprotective. I try to protect myself from a lot of stuff, you know. You only get one life. So, some people are different.” However, others acknowledged that even if someone is committed to taking PrEP, maintaining regular medical visits can be difficult. Another participant noted, “I think some people may just take the medication but just not go to the doctor, as they’re supposed to. It’s not to say it's going to stop them from taking the medicine, but they just might not go to the doctor every three months like they're supposed to.” This suggests that the video could further emphasize solutions for making healthcare more accessible and convenient.
Additionally, the conversation explored the practicability of taking PrEP alongside birth control, a common concern among participants. Some felt confident in their ability to manage both medications, with one stating, “Fine, because if you can remember to take your birth control pill every day, you're going to remember to take the PrEP too.” However, others pointed out the challenges of maintaining a daily medication routine. One participant shared, “I always miss my birth control pills because I have alarms. Sometimes I'm like, 'Oh my god. It's nine o’clock,' and I miss my pill. I'm not really good with pills, to be honest. I'm not really good with it, but I try my best or I'll ask somebody else to remind me. But if it’s important like that, I feel like it should be a priority.” This suggests that the video could acknowledge real-life struggles with adherence and offer practical strategies for staying on track. Beyond forgetfulness, concerns about misuse also emerged, with some participants expressing worry that individuals might treat PrEP similarly to birth control, believing they could compensate for missed doses or use it as a justification for engaging in riskier behaviors.
One participant explained, “I kind of just look at this stuff like, just like the birth control pill, women who use the birth control pill will use the PrEP. But I feel like people would be less responsible as far as, like, with the birth control pill. 'Oh, I just missed a day. I can just double up this day,' or 'I could have unprotected sex, but I know if I just take the pill...' or 'If I take the PrEP, if I double up this day, I can have unprotected sex this day.' People will abuse it like they abuse everything else.”
This concern suggests that the video could benefit from reinforcing clear messaging about proper PrEP adherence and dispelling misconceptions about its use.
Empowerment Through Health Autonomy
The video’s message about taking PrEP as an act of self-care resonated strongly, reinforcing the importance of prioritizing one’s health over others’ opinions. The main character in “Put Yourself First” emphasized taking PrEP for oneself rather than for others. Participants recognized the significance of making their own health decisions without feeling pressured to seek validation or approval from others, especially their partners. One participant said, “I just don't feel like he needs to know that. It's going to lead to another conversation. I don't think he needs to know everything. They don't need to know every detail because they don't tell us every detail.” This quote underscores the belief that women should have autonomy over their health choices and should not feel pressured to disclose every aspect of their health care decisions. Another participant reinforced this perspective, asserting, “You don't have to tell your partner about it,” highlighting that PrEP use is a personal choice and women should feel empowered to take control of their sexual health on their own terms. Affirming this theme of self-determination, another participant stated, “You're doing it for yourself at the end of the day,” further emphasizing the message that prioritizing one's health is an act of self-care and autonomy. Overall, these scenarios and messages were praised for authentically representing the realities and concerns of young Black women considering PrEP. Participants particularly valued the framing of PrEP as an act of self-care and empowerment, resonating with sex-positive narratives that affirm women’s right to prioritize both protection and pleasure in their intimate lives.
Domains Requiring Further Development
outlines the domains identified by the participants that require further development to enhance the educational video about PrEP for future research. While participants found the video informative, they identified areas for enhancement to increase its relatability and impact. Participants suggested making future videos more relatable by incorporating real-life characters and scenarios to enhance impact and engagement. Participants suggested incorporating more storylines that reflect women’s daily lives and strategies for addressing the challenges and barriers to PrEP use, as well as adding depth to character interactions to make the video more engaging. They recommended replacing animations with real women to create a stronger emotional connection and enhance trustworthiness. While participants appreciated the inclusion of details about PrEP, they expressed concerns that highlighting side effects, such as nausea, could discourage viewers. They suggested presenting sufficient information to educate without overly emphasizing negative aspects, ensuring the benefits of PrEP remain central. Overall, the recommendations aim to enhance the video’s realism, solution-oriented approach, and impact by equipping the target audience with the skills necessary to address challenges related to accessing and maintaining PrEP adherence.
| Area of focus | Critical feedback | Suggestions for improvement | Illustrative quotes |
| Scenario | Realism and relatability: While the video was informative, but it lacked the realism needed to resonate with the target audience fully. | More realistic storylines: Participants suggested adding a storyline that more authentically reflects women\'s daily lives and challenges to make the video feel more genuine and engaging. Adding more depth to the character dynamics and their interactions could make the video feel even more realistic. |
|
| Characters | Character relatability: While the characters conveyed the message well, some participants felt the group’s dynamic was a bit unusual. | Using real characters: Participants wanted to see real women (humans instead of animation) discussing PrEPa, as they felt this would make the message more trustworthy and more straightforward to connect with. |
|
| Content | Side effects mentioned: Some participants felt that discussing potential side effects, like nausea, could be off-putting or scare potential users. | Balancing details: Participants wanted enough information to be well-informed but felt that too many details, especially about side effects, might discourage viewers from considering PrEP. |
|
aPrEP: preexposure prophylaxis.
Discussion
Principal Findings
This study evaluated “Put Yourself First,” a culturally tailored, sex-positive, animated eHealth video intervention designed to increase PrEP awareness among young Black women. Participants found the video to be engaging, relatable, and informative, reporting increased knowledge of PrEP, a heightened willingness to consider it, and strong intentions to recommend it to their peers. Participants’ feedback suggested the importance of representation, authenticity, and the normalization of PrEP use for women, indicating the need for culturally resonant multimedia to enhance HIV prevention messaging. However, they also identified several aspects that could be refined to enhance its impact and resonance with the target audience.
Focus group findings demonstrate that the video was both engaging and educational, with participants praising its clarity, appeal, and ability to dispel misconceptions, such as the notion that PrEP is exclusively for gay men, while emphasizing its relevance and safety for women. These results align with prior research highlighting the importance of culturally tailored and gender-specific messaging in increasing PrEP awareness among women [,,]. Importantly, these findings extend earlier exploratory studies [] by demonstrating that an intervention explicitly grounded in sex-positive and empowerment frameworks can enhance knowledge while also resonating emotionally with the target audience. Previous research has shown that interventions can be enhanced by improving communication about sexual health within a young Black woman’s social network, particularly with emotionally supportive friends and family []. The conversational format among friends was viewed as authentic and relatable because it included a peer-to-peer exchange that mirrored participants’ real-life discussions. In edutainment, content is presented in ways that feel authentic and familiar, such as the script of the video, which conveys information on PrEP through a conversation among friends []. This educational method allowed the participants to see themselves or people like them. When people see peers (or peer characters) discussing, modeling, or demonstrating healthy behaviors, it helps participants believe that the behavior is possible, socially acceptable, and relevant []. The peer-to-peer exchange also models collectivism among Black women and communities [].
At the same time, women identified relational challenges, particularly the tension between prioritizing their own health and concerns about partner perceptions, which reflects broader gendered and racialized dynamics that influence sexual health decision-making among Black women [,-]. This reflects intersectional dynamics that Black women experience [,], where their overlapping identities, gendered expectations, and experience of racialized stigma impact structural inequities and constrain women’s HIV prevention options. Finally, the video’s framing of PrEP as an act of self-care and empowerment resonated strongly, affirming women’s right to make autonomous decisions about their sexual health. This finding contributes to the literature on sex-positive and empowerment-based approaches to HIV prevention, emphasizing the importance of interventions that affirm pleasure, center health autonomy and agency rather than relying solely on risk framing [,]. Together, these insights suggest that narrative-based, culturally resonant, and empowerment-framed interventions may be particularly effective for increasing PrEP engagement among Black women.
Although the video has notable strengths, participants noted several challenges that could limit its acceptability. While the video was informative, some participants found the use of animation somewhat limiting in fostering deep emotional connection and trust. They suggested incorporating real-life testimonials from women who use PrEP, live-action scenarios, or documentary-style storytelling on topics such as conversations with partners, health care visits, or navigating daily life while on PrEP, to enhance authenticity and relatability in PrEP-focused edutainment content []. There was a strong desire to see more authentic scenarios depicting real challenges women face when discussing PrEP with partners and health care providers, such as fear of judgment, accusations of infidelity, or adverse partner reactions. This aligns with prior studies highlighting the central role of interpersonal stigma and relationship dynamics in shaping women’s PrEP decision-making []. While women view PrEP as a tool for maintaining health and relationships, women’s romantic feelings and expectations can affect their risk perceptions and interest in using PrEP []. Imbalanced relationship dynamics, including power struggles, infidelity concerns, and trust issues, significantly influenced women’s PrEP decisions []. In addition, framing PrEP within a sex-positive, empowering context that aligns with women’s reproductive values may increase uptake [,]. These strategies not only enhance authenticity but also align with principles of edutainment, where culturally resonant narratives and modeled behaviors transform health information into engaging, meaningful content that promotes learning and supports behavior change.
Along with increasing awareness, participants emphasized the importance of directly tackling the institutional constraints that influence women’s PrEP decisions. They described persistent challenges, such as PrEP stigma, frequent medical visits, medical mistrust, and challenges with daily pill adherence, which often parallel their experiences with birth control [-]. Although the video demonstrated PrEP’s effectiveness, it did not fully address structural concerns, such as navigating the health care system, financial accessibility, or alternative care models, including pharmacy-based PrEP access or telehealth services [-]. Taken together, these findings emphasize the importance of advancing practice innovations that reduce both structural and interpersonal barriers through accessible care models, stigma-free environments, and culturally responsive provider communication. To enhance the impact of future interventions, messaging should include practical strategies to overcome these barriers, such as highlighting mail-order PrEP services, home HIV or STI testing kits, and financial assistance programs []. At the same time, future research is needed to evaluate multilevel strategies that address these barriers and generate evidence on how best to sustain equitable PrEP uptake among Black women. Such efforts will be crucial to ensuring that PrEP implementation not only increases awareness but also translates into meaningful improvements in HIV prevention outcomes []. Finally, these findings suggest the importance of expanding insurance coverage, integrating PrEP into reproductive and primary care services, and funding community-based initiatives that directly address the structural inequities limiting Black women’s access to HIV prevention [].
In addition to addressing these structural barriers, it is crucial to consider how the “Put Yourself First” video can be disseminated most effectively. The findings emphasize the importance of designing HIV prevention interventions that not only raise awareness but also facilitate direct connections to services. Future dissemination strategies should leverage trusted community-based organizations, college health centers, sexual and reproductive health clinics, and digital platforms (both social networks and institutional services) to maximize reach and engagement among young Black women [,,]. To ensure that the awareness generated by the video translates into tangible access to PrEP-related services and strengthens its real-world impact, direct referral pathways could be embedded within these dissemination channels, such as integrating links to PrEP locators, telehealth services, or peer navigation programs [,-]. By pairing education with actionable referral tools, the intervention can more directly support women in moving from interest to uptake. These strategies can help bridge the persistent gap between PrEP awareness and actual uptake, ensuring that dissemination efforts are linked to concrete service access and continuity of care [,].
Limitations
Several limitations warrant consideration. The findings are based on a small sample of young Black women from a single urban location, which limits their generalizability. Future work should extend recruitment to multiple geographic regions, including the South and rural communities where HIV disparities are most pronounced. Black women’s experiences are diverse and shaped by intersecting factors such as age, sexuality, and socioeconomic status. Future studies should purposively sample across these intersecting identities to capture heterogeneity within the population. While knowledge gains and acceptability outcomes were encouraging, the findings should be interpreted with caution, as they were not uniformly significant across all groups (eg, Group 4). Participants continued to express concerns about side effects, daily adherence, and structural barriers, such as frequent medical visits and medical mistrust. The evaluation was limited to immediate outcomes and did not assess downstream behaviors such as PrEP initiation or adherence. Participants also explicitly called for greater realism through live-action or testimonial-based storytelling and requested deeper engagement with structural barriers such as stigma, provider bias, and medical mistrust. These mixed findings temper the conclusions and highlight the need for future studies to address both behavioral and structural outcomes in addition to knowledge and acceptability. Longitudinal and controlled studies are needed to evaluate whether such interventions increase actual PrEP uptake and adherence. By incorporating these refinements, future studies can better bridge the gap between pilot findings and real-world application, ensuring that dissemination strategies not only raise awareness but also facilitate access and sustained use of PrEP.
Although no new themes emerged after the second focus group, the small qualitative sample limits the claim of saturation. Focus group methodologists typically recommend 3-5 groups per relatively homogeneous population to ensure adequate coverage of perspectives, suggesting that saturation should be monitored across, rather than within, groups [,]. While Guest and colleagues [] demonstrated that most themes emerge within 6-12 participants, a benchmark often used to justify 2-3 focus groups for achieving saturation. This analysis of the explanatory focus groups aligns with this range, as it is a relatively homogeneous sample and the study consisted of targeted research questions. Additionally, focus group settings may have introduced social desirability bias, potentially leading participants to overemphasize favorable responses about the video. This study did not include specific methodological steps recommended by COREQ. For example, reasons for nonparticipation were not collected, field notes were not taken during focus groups, and transcripts were not returned to participants for validation. While focus groups were co-led by trained facilitators who shared social identities with participants, reflexivity was addressed through consensus-based coding discussions rather than participant checking of themes. These omissions may have limited opportunities to triangulate interpretations or further ensure the credibility of findings. Despite these limitations, the study provides critical insights into the acceptability and impact of a culturally tailored, sex-positive eHealth intervention video, offering a valuable foundation for refining and scaling PrEP promotion strategies for young Black women. This study reinforces existing research that demonstrates the effectiveness of culturally relevant, video-based educational interventions in improving engagement and increasing knowledge of PrEP among Black women [,,].
Conclusion
This study highlights the critical need for culturally tailored interventions to enhance PrEP awareness and uptake among young Black women. This research emphasizes the importance of using sex-positive, engaging, and culturally affirming sexuality educational tools to address the ongoing barriers of stigma, misinformation, and health care inequities. By embedding PrEP within sex-positive and empowerment frameworks, this study contributes novel evidence that HIV prevention can be framed not only as risk reduction but also as a pathway to autonomy, intimacy, and pleasure. The findings show that eHealth interventions, especially edutainment animated videos, can effectively raise awareness, dispel misconceptions, and encourage informed decision-making regarding PrEP. These findings will guide future iterations, examining the long-term effects of eHealth video interventions on PrEP uptake and adherence and ensuring that dissemination strategies extend beyond awareness to support real-world access and sustained PrEP use. Ultimately, this study emphasizes the transformative potential of culturally competent and innovative health communication strategies in tackling disparities and empowering Black women to take control of their sexual health. Centering women’s voices, addressing structural barriers, and affirming pleasure and agency must remain central as PrEP interventions continue to evolve.
Acknowledgments
This article and the research behind it would not have been possible without the exceptional support of staff at Project HEAT and Acria, Inc.
Funding
This research is supported by the Center for Drug Use and HIV Research (CDUHR-P30 DA011041), New York Center for Advancing Translational Research and Health (U54MD017979) and the National Institute of Mental Health (R25MH087217). The content of this paper is solely the responsibility of the authors and does not represent the official views of the National Institutes of Health.
Authors' Contributions
KTB led the conceptualization, methodology, investigation, formal analysis, writing of the original draft, supervision, project administration, and funding acquisition. PW contributed to the investigation, data curation, and formal analysis, and participated equally in reviewing and editing the manuscript. PT contributed equally to the review and editing of the manuscript. DB supported visualization efforts and assisted with reviewing and editing. AG contributed to the conceptualization and led the formal analysis and participated equally in reviewing and editing the manuscript.
Conflicts of Interest
KB is an Associate Editor of JMIR Formative Research at the time of this publication. The other authors declare no conflicts of interest.
References
- Estimated HIV incidence and prevalence in the United States, 2018-2022. Centers for Disease Control and Prevention. 2024. URL: https://www.cdc.gov/hiv-data/nhss/estimated-hiv-incidence-and-prevalence.html [accessed 2026-02-05]
- Women and HIV preexposure prophylaxis (PrEP). Centers for Disease Control and Prevention. 2018. URL: https://www.cdc.gov/hiv/pdf/group/gender/women/cdc-hiv-women-and-PrEP-discussion-series.pdf [accessed 2026-02-05]
- Baugher AR, Trujillo L, Kanny D, Freeman JQ, Hickey T, Sionean C, et al. National HIV Behavioral Surveillance Study Group. Racial, ethnic, and gender disparities in awareness of preexposure prophylaxis among HIV-negative heterosexually active adults at increased risk for HIV infection - 23 Urban Areas, United States, 2019. MMWR Morb Mortal Wkly Rep. 2021;70(47):1635-1639. [FREE Full text] [CrossRef] [Medline]
- Nydegger LA, Dickson-Gomez J, Ko TK. Structural and syndemic barriers to PrEP adoption among Black women at high risk for HIV: a qualitative exploration. Cult Health Sex. May 2021;23(5):659-673. [FREE Full text] [CrossRef] [Medline]
- Chandler R, Guillaume D, Wells J, Hernandez N. Let me prep you to PREP me: amplifying the voices of Black women and their providers to consider prep as an HIV prevention option. Int J Environ Res Public Health. 2022;19(3):1414. [CrossRef] [Medline]
- Bond KT, Gunn A, Williams P, Leonard NR. Using an intersectional framework to understand the challenges of adopting pre-exposure prophylaxis (PrEP) among young adult Black women. Sex Res Social Policy. 2022;19(1):180-193. [FREE Full text] [CrossRef] [Medline]
- Devlin SA, Ridgway JP, Dawdani A, Enaholo OE, Liegeon G, Kasal N, et al. Adapting provider training and pre-exposure prophylaxis advertising to increase pre-exposure prophylaxis awareness and uptake among Black cisgender women. AIDS Patient Care STDS. 2023;37(12):574-582. [CrossRef] [Medline]
- Bond KT, Gunn AJ. Perceived advantages and disadvantages of using pre-exposure prophylaxis (PrEP) among sexually active Black women: an exploratory study. J Black Sex Relatsh. 2016;3(1):1-24. [FREE Full text] [CrossRef] [Medline]
- Randolph SD, Johnson R, Johnson A, Keusch A. Using PrEP and Doing it for Ourselves (UPDOs Protective Styles), a Web-Based Salon Intervention to Improve Uptake of Pre-exposure Prophylaxis Among Black Women: Protocol for a Pilot Feasibility Study. JMIR Res Protoc. 2022;11(8):e34556. [FREE Full text] [CrossRef] [Medline]
- Chandler-Coley R, Ross H, Ozoya O, Lescano C, Flannigan T. Exploring Black college females' perceptions regarding HIV prevention message content. J Health Commun. 2017;22(2):102-110. [FREE Full text] [CrossRef] [Medline]
- Tekeste M, Hull S, Dovidio JF, Safon CB, Blackstock O, Taggart T, et al. Differences in medical mistrust between Black and White women: implications for patient-provider communication about PrEP. AIDS Behav. 2019;23(7):1737-1748. [CrossRef] [Medline]
- Chapman Lambert C, Marrazzo J, Amico RK, Mugavero MJ, Elopre L. PrEParing women to prevent HIV: an integrated theoretical framework to prEP Black women in the United States. J Assoc Nurses AIDS Care. 2018;29(6):835-848. [CrossRef] [Medline]
- Bond KT, Chandler R, Chapman-Lambert C, Jemmott LS, Lanier Y, Cao J, et al. Applying a nursing perspective to address the challenges experienced by cisgender women in the HIV status neutral care continuum: a review of the literature. J Assoc Nurses AIDS Care. 2021;32(3):283-305. [FREE Full text] [CrossRef] [Medline]
- George S, Moran E, Duran N, Jenders RA. Using animation as an information tool to advance health research literacy among minority participants. AMIA Annu Symp Proc. 2013;2013:475-484. [Medline]
- Bello-Bravo J, Tamò M, Dannon EA, Pittendrigh BR. An assessment of learning gains from educational animated videos versus traditional extension presentations among farmers in Benin. Inf Technol Dev. 2017;24(2):224-244. [CrossRef]
- Keller S, McNeill V, Tran T. The perceived stigma reduction expressed by young adults in response to suicide prevention videos. Int J Environ Res Public Health. 2021;18(12):6180. [FREE Full text] [CrossRef] [Medline]
- Pinto RM, Berringer KR, Melendez R, Mmeje O. Improving PrEP implementation through multilevel interventions: a synthesis of the literature. AIDS Behav. 2018;22(11):3681-3691. [FREE Full text] [CrossRef] [Medline]
- Adam M, McMahon SA, Prober C, Bärnighausen T. Human-centered design of video-based health education: an iterative, collaborative, community-based approach. J Med Internet Res. 2019;21(1):e12128. [FREE Full text] [CrossRef] [Medline]
- Galmarini E, Marciano L, Schulz PJ. The effectiveness of visual-based interventions on health literacy in health care: a systematic review and meta-analysis. BMC Health Serv Res. 2024;24(1):718. [FREE Full text] [CrossRef] [Medline]
- Dahodwala M, Geransar R, Babion J, de Grood J, Sargious P. The impact of the use of video-based educational interventions on patient outcomes in hospital settings: a scoping review. Patient Educ Couns. 2018;101(12):2116-2124. [CrossRef] [Medline]
- Bond KT, Ramos SR. Utilization of an animated electronic health video to increase knowledge of post- and pre-exposure prophylaxis for HIV among African American women: nationwide cross-sectional survey. JMIR Form Res. 2019;3(2):e9995. [CrossRef] [Medline]
- Calabrese SK, Lane SB, Caldwell A, Kaplan C, Dovidio JF, Galvao RW, et al. Electronic dissemination of a web-based video promotes PrEP contemplation and conversation among US women engaged in care at planned parenthood. AIDS Behav. 2021;25(8):2483-2500. [CrossRef] [Medline]
- Matos LA, Lujan RA. Culturally targeted video intervention to increase PrEP use intentions among latinx sexual minority men: a pilot randomized controlled trial. Hisp Health Care Int. 2024;22(3):133-141. [CrossRef] [Medline]
- Prawesti I, Haryanti F, Lusmilasari L. Effect of health education using video and brochure on maternal health literacy. Belitung Nurs J. 2018;4(6):612-618. [CrossRef]
- Bond KT, Leblanc NM, Williams P, Gabriel CA, Amutah-Onukagha NN. Race-based sexual stereotypes, gendered racism, and sexual decision making among young Black cisgender women. Health Educ Behav. 2021;48(3):295-305. [FREE Full text] [CrossRef] [Medline]
- Conley C, Johnson R, Bond K, Brem S, Salas J, Randolph S. US Black cisgender women and pre-exposure prophylaxis for human immunodeficiency virus prevention: a scoping review. Womens Health (Lond). 2022;18:17455057221103098. [FREE Full text] [CrossRef] [Medline]
- Young AM, Fruhauf T, Okonkwo O, Gingher E, Coleman J. Developing educational animations on HIV pre-exposure prophylaxis (PrEP) for women: qualitative study. JMIR Form Res. 2022;6(7):e33978. [FREE Full text] [CrossRef] [Medline]
- Smit F, Masvawure TB. Barriers and facilitators to acceptability and uptake of pre-exposure prophylaxis (PrEP) among Black women in the United States: a systematic review. J Racial Ethn Health Disparities. 2024;11(5):2649-2662. [CrossRef] [Medline]
- Nydegger LA, Dickson-Gomez J, Ko Ko T. A longitudinal, qualitative exploration of perceived HIV risk, healthcare experiences, and social support as facilitators and barriers to prep adoption among Black women. AIDS Behav. 2021;25(2):582-591. [FREE Full text] [CrossRef] [Medline]
- Muschialli L, Ford JV, Gonsalves L, Pralat R. Prevent with Pleasure: a systematic review of HIV public communication campaigns incorporating a pleasure-based approach. PLOS Glob Public Health. 2025;5(3):e0004005. [CrossRef]
- Bond KT, Radix AE. Sexual health and well-being: a framework to guide care. Med Clin North Am. 2024;108(2):241-255. [CrossRef] [Medline]
- Crenshaw K. Demarginalizing the intersection of race and sex: a Black feminist critique of antidiscrimination doctrine, feminist theory and antiracist politics. In: University of Chicago Legal Forum. Milton Park, UK. Routledge; 1989:24.
- Collins PH. Black Feminist Thought: Knowledge, Consciousness, and the Politics of Empowerment. Milton Park, UK. Routledge; 2002.
- Flay BR, Snyder FJ, Petraitis J. The theory of triadic influence. In: Emerging Theories in Health Promotion Practice and Research. California, USA. Jossey-Bass/Wiley; 2009:451-510.
- Fisher JD, Fisher WA, Shuper PA. The information-motivation-behavioral skills model of HIV preventive behavior. In: Emerging Theories in Health Promotion Practice and Research. California, USA. Jossey-Bass/Wiley; 2009:21-63.
- Wang Q, Tan W, Song B. Research and design of edutainment. IEEE; 2007. Presented at: Information Technologies and Applications in Education, 2007. ISITAE '07. First IEEE International Symposium on; 2007 November 23–25:502-505; Kunming, China. [CrossRef]
- Singhal A, Cody MJ, Rogers EM, Sabido M. Entertainment-Education and Social Change: History, Research, and Practice. New Jersey. Lawrence Erlbaum Associates; 2004.
- Bartholomew LK, Parcel GS, Kok G. Intervention mapping: a process for developing theory- and evidence-based health education programs. Health Educ Behav. 1998;25(5):545-563. [CrossRef] [Medline]
- HIV among women in New York City, 2023. New York City Department of Health and Mental Hygiene. 2024. URL: https://www.nyc.gov/assets/doh/downloads/pdf/dires/hiv-among-women-2023.pdf [accessed 2025-08-05]
- Kubicek K, Arauz-Cuadra C, Kipke MD. Attitudes and perceptions of biomedical HIV prevention methods: voices from young men who have sex with men. Arch Sex Behav. 2015;44(2):487-497. [CrossRef] [Medline]
- Johnson BT, Scott-Sheldon LAJ, Huedo-Medina TB, Carey MP. Interventions to reduce sexual risk for human immunodeficiency virus in adolescents: a meta-analysis of trials, 1985-2008. Arch Pediatr Adolesc Med. 2011;165(1):77-84. [FREE Full text] [CrossRef] [Medline]
- Pulerwitz J, Gortmaker SL, DeJong W. Measuring sexual relationship power in HIV/STD research. Sex Roles. 2000;42(7-8):637-660. [CrossRef]
- Brafford LJ, Beck KH. Development and validation of a condom self-efficacy scale for college students. J Am Coll Health. 1991;39(5):219-225. [CrossRef] [Medline]
- Berger BE, Ferrans CE, Lashley FR. Measuring stigma in people with HIV: psychometric assessment of the HIV stigma scale. Res Nurs Health. 2001;24(6):518-529. [CrossRef] [Medline]
- Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care. 2007;19(6):349-357. [CrossRef] [Medline]
- IBM and AWS partner to accelerate transformation. IBM Corp. 2023. URL: https://www.ibm.com/in-en [accessed 2026-02-05]
- Dedoose Version 9.0.17. Dedoose. 2021. URL: https://www.dedoose.com/release-features/9-0 [accessed 2026-02-05]
- Patton MQ. Qualitative Evaluation and Research Methods. Thousand Oaks, CA. Sage Publications, Inc; 1990:532.
- Strauss AL, Corbin JM. Grounded Theory in Practice. Thousand Oaks, CA. Sage Publications, Inc; 1997:489.
- Bowen GA. Naturalistic inquiry and the saturation concept: a research note. Qua Res. 2008;8(1):137-152. [CrossRef]
- Creswell JW. Qualitative Inquiry and Research Design: Choosing Among Five Approaches. Thousand Oaks, CA. Sage Publications; 2013.
- Hennink M, Kaiser BN. Sample sizes for saturation in qualitative research: a systematic review of empirical tests. Soc Sci Med. 2022;292:114523. [FREE Full text] [CrossRef] [Medline]
- Auerbach JD, Kinsky S, Brown G, Charles V. Knowledge, attitudes, and likelihood of pre-exposure prophylaxis (PrEP) use among US women at risk of acquiring HIV. AIDS Patient Care STDS. 2015;29(2):102-110. [FREE Full text] [CrossRef] [Medline]
- Flash C, Landovitz R, Giler RM, Ng L, Magnuson D, Wooley SB, et al. Two years of truvada for pre-exposure prophylaxis utilization in the US. J Int AIDS Soc. 2014;17(4 Suppl 3):19730. [FREE Full text] [CrossRef] [Medline]
- Ware S, Thorpe S, Tanner AE. Sexual health interventions for Black women in the United States: a systematic review of literature. Int J Sex Health. 2019;31(2):196-215. [CrossRef]
- Bowleg L. The problem with the phrase women and minorities: intersectionality-an important theoretical framework for public health. Am J Public Health. 2012;102(7):1267-1273. [CrossRef] [Medline]
- Wingood GM, Scd, DiClemente RJ. Application of the theory of gender and power to examine HIV-related exposures, risk factors, and effective interventions for women. Health Educ Behav. 2000;27(5):539-565. [CrossRef] [Medline]
- Amaro H, Raj A, Reed E. Women's sexual health: the need for feminist analyses in public health in the decade of behavior. Psychol Women Q. 2001;25(4):324-334. [CrossRef]
- Dworkin SL, Fleming PJ, Colvin CJ. The promises and limitations of gender-transformative health programming with men: critical reflections from the field. Cult Health Sex. 2015;17(sup2):S128-S143. [CrossRef] [Medline]
- Clement ME, Perry B, McKenna K, Beckford J, Davenport T, Murray E, et al. Identifying implementation strategies to enhance hiv pre-exposure prophylaxis uptake among black cisgender women in new Orleans, Louisiana. AIDS Patient Care STDS. 2024;38(3):144-150. [CrossRef] [Medline]
- Johnson BT, Michie S, Snyder LB. Effects of behavioral intervention content on HIV prevention outcomes: a meta-review of meta-analyses. J Acquir Immune Defic Syndr. 2014;66(Suppl 3):S259-S270. [CrossRef] [Medline]
- Hartmann M, Lanham M, Palanee-Phillips T, Mathebula F, Tolley EE, Peacock D, et al. CHARISMA team. Generating CHARISMA: development of an intervention to help women build agency and safety in their relationships while using PrEP for HIV prevention. AIDS Educ Prev. 2019;31(5):433-451. [FREE Full text] [CrossRef] [Medline]
- Willie TC, Keene DE, Kershaw TS, Stockman JK. "You Never Know What Could Happen": women's perspectives of pre-exposure prophylaxis in the context of recent intimate partner violence. Womens Health Issues. 2020;30(1):41-48. [FREE Full text] [CrossRef] [Medline]
- Montgomery MC, Oldenburg CE, Nunn AS, Mena L, Anderson P, Liegler T, et al. Adherence to pre-exposure prophylaxis for HIV prevention in a clinical setting. PLoS One. 2016;11(6):e0157742. [CrossRef] [Medline]
- Murphy EC, Danvers A, Zamudio AR, Avila K, Proehl M, Gonzalez-Argoti T, et al. "Being able to do whatever you wanna do as a woman is important:" a qualitative exploration of contraception as a frame of reference for HIV prevention with PrEP. Reprod Health. 2022;19(1):92. [CrossRef] [Medline]
- Randolph SD, Golin C, Welgus H, Lightfoot AF, Harding CJ, Riggins LF. How perceived structural racism and discrimination and medical mistrust in the health system influences participation in HIV health services for black women living in the United States South: a qualitative, descriptive study. J Assoc Nurses AIDS Care. 2020;31(5):598-605. [CrossRef] [Medline]
- Karris MY, Beekmann SE, Mehta SR, Anderson CM, Polgreen PM. Are we prepped for preexposure prophylaxis (PrEP)? Provider opinions on the real-world use of PrEP in the United States and Canada. Clin Infect Dis. 2014;58(5):704-712. [FREE Full text] [CrossRef] [Medline]
- Wang Y, Mitchell JW, Zhang C, Liu Y. Evidence and implication of interventions across various socioecological levels to address pre-exposure prophylaxis uptake and adherence among men who have sex with men in the United States: a systematic review. AIDS Res Ther. 2022;19(1):28. [CrossRef] [Medline]
- Meyers K, Golub SA. Planning ahead for implementation of long-acting HIV prevention: challenges and opportunities. Curr Opin HIV AIDS. 2015;10(4):290-295. [CrossRef] [Medline]
- Chory A, Bond K. Access to PrEP and other sexual health services for cisgender women in the United States: a review of state policy and medicaid expansion. Front Public Health. 2024;12:1360349. [FREE Full text] [CrossRef] [Medline]
- Morgan DL. Focus Groups as Qualitative Research. Thousand Oaks, CA. Sage Publications; 2009.
- Krueger RA. Focus Groups: A Practical Guide for Applied Research. Thousand Oaks, CA. Sage Publications; 2014.
- Guest G, Bunce A, Johnson L. How many interviews are enough? Field Methods. 2006;18(1):59-82. [CrossRef]
- Downing MJ, Wiatrek SE, Zahn RJ, Mansergh G, Olansky E, Gelaude D, et al. Video selection and assessment for an app-based HIV prevention messaging intervention: formative research. Mhealth. 2023;9:2. [FREE Full text] [CrossRef] [Medline]
Abbreviations
| BAB: Brief Assessment Battery |
| BFT: Black Feminist Thought |
| CDC: Centers for Disease Control and Prevention |
| COREQ: Consolidated Criteria for Reporting Qualitative Research |
| IMB: Information-Motivation-Behavioral Skills |
| LOVE: Learning Options through Video Education |
| PrEP: preexposure prophylaxis |
| STI: sexually transmitted infection |
| TTI: Theory of Triadic Influence |
Edited by A Mavragani, J Sarvestan; submitted 18.Mar.2025; peer-reviewed by M Pyra; comments to author 27.Jun.2025; revised version received 21.Sep.2025; accepted 01.Oct.2025; published 26.Feb.2026.
Copyright©Keosha T Bond, Porche M Williams, Portia Thomas, David Babayev, Alana Gunn. Originally published in JMIR Formative Research (https://formative.jmir.org), 26.Feb.2026.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Formative Research, is properly cited. The complete bibliographic information, a link to the original publication on https://formative.jmir.org, as well as this copyright and license information must be included.

