The Impact of Intervention Design on User Engagement in Digital Therapeutics Research: Factorial Experiment With a Mixed Methods Study

Hyerim Lee   ¹ , BA ;   Eung Ho Choi   ² , PhD ;   Jung U Shin   ³ , PhD ;   Tae-Gyun Kim   ⁴ , PhD ;   Jooyoung Oh   ^{5, 6} , PhD ;   Bokyoung Shin   ⁷ , MA ;   Jung Yeon Sim   ⁸ , MA ;   Jaeyong Shin   ^{9 *} , PhD ;   Meelim Kim   ^{9, 10, 11, 12 *} , PhD

¹ Department of Psychology, College of Liberal Arts, Yonsei University, Seoul, Republic of Korea

² Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea

³ Department of Dermatology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea

⁴ Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea

⁵ Department of Psychiatry, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea

⁶ Institute of Behavioral Sciences in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea

⁷ Department of Integrative Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea

⁸ Department of Medical Device Engineering and Management, Yonsei University Graduate School, Seoul, Republic of Korea

⁹ Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea

¹⁰ Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, San Diego, CA, United States

¹¹ The Design Lab, University of California San Diego, San Diego, CA, United States

¹² Center for Wireless & Population Health Systems, Calit2’s Qualcomm Institute, University of California San Diego, San Diego, CA, United States

*these authors contributed equally