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The Role of Depressive Symptoms and Physical Activity Levels in Mediating the Association Between HIV Status and Neurocognitive Functions Among Individuals Aged at Least 50 Years in China: Cross-sectional Study

The Role of Depressive Symptoms and Physical Activity Levels in Mediating the Association Between HIV Status and Neurocognitive Functions Among Individuals Aged at Least 50 Years in China: Cross-sectional Study

HIV infection is a risk factor of neurocognitive impairment. Studies showed older people living with HIV had poorer neurocognitive function as compared to HIV-negative individuals [10-12]. Neurocognitive impairment is prevalent and consequential among older people living with HIV [13]. The Central Nervous System HIV Antiretroviral Therapy Effects Research study reported that nearly half of people living with HIV suffered from neurocognitive impairment [13].

Pei Qin, Jianmei He, Xue Yang, Siyu Chen, Xi Chen, Hui Jiang, Ada Wai Tung Fung, Zixin Wang, Joseph Tak Fai Lau

JMIR Public Health Surveill 2022;8(8):e32968

Correlations Between Facial Expressivity and Apathy in Elderly People With Neurocognitive Disorders: Exploratory Study

Correlations Between Facial Expressivity and Apathy in Elderly People With Neurocognitive Disorders: Exploratory Study

Apathy is one of the most common neuropsychiatric symptoms in neurocognitive disorders (NCDs) such as Alzheimer disease, Parkinson disease, Huntington disease, and vascular dementia and is prevalent in several psychiatric pathologies such as schizophrenia and major depression [1]. It can be defined as a reduction in goal-directed behavior that persists over time causing impairment in global functioning.

Radia Zeghari, Alexandra König, Rachid Guerchouche, Garima Sharma, Jyoti Joshi, Roxane Fabre, Philippe Robert, Valeria Manera

JMIR Form Res 2021;5(3):e24727

A Mobile App to Screen for Neurocognitive Impairment: Preliminary Validation of NeuroScreen Among HIV-Infected South African Adults

A Mobile App to Screen for Neurocognitive Impairment: Preliminary Validation of NeuroScreen Among HIV-Infected South African Adults

Neurocognitive impairment in HIV, known as HIV-associated neurocognitive disorder (HAND) when HIV is determined to be the etiology, typically causes impairments in mental processing speed, learning, memory, attention and concentration, executive functions, and motor speed [6,9,10]. It ranges in severity from asymptomatic and mild forms to a severe dementia-type form [11].

Reuben N N Robbins, Hetta Gouse, Henry G Brown, Andries Ehlers, Travis M Scott, Cheng-Shiun Leu, Robert H Remien, Claude A Mellins, John A Joska

JMIR Mhealth Uhealth 2018;6(1):e5