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Efficacy of a Self-Guided Transdiagnostic Intervention for Adults With Anxiety and Depression: Randomized Controlled Trial

Efficacy of a Self-Guided Transdiagnostic Intervention for Adults With Anxiety and Depression: Randomized Controlled Trial

The Headspace Anxiety and Depression Program integrates CBT and mindfulness techniques similar to the approach used in the UP, a transdiagnostic approach to reducing anxiety and depression symptoms (Multimedia Appendix 2).

Walter Staiano, Christine E Callahan, Michelle Davis, Leah Tanner, Sarah Kunkle, Jenna Glover, Jon Kole, Neeru Bakshi, Marco Romagnoli, Ulrich Kirk

JMIR Mhealth Uhealth 2025;13:e79759


Effectiveness of a Mindfulness-Based Mobile Intervention for Improving Perinatal Mental Health and Reducing Depression During Pregnancy: Randomized Controlled Trial

Effectiveness of a Mindfulness-Based Mobile Intervention for Improving Perinatal Mental Health and Reducing Depression During Pregnancy: Randomized Controlled Trial

Mindfulness practice is increasingly being recognized as an effective approach for alleviating perinatal mental health problems. Mindfulness is defined as “paying attention in a particular way: on purpose, in the present moment, and nonjudgmentally” [8]. Mindfulness meditation enhances mental health by increasing awareness and altering responses to negative emotions.

Minjung Kim, Jin Young Park, Sehwan Park, Kyungmi Chung, Hee Young Cho, Gangho Do, Kyungun Jhung

J Med Internet Res 2025;27:e75630


Bedtime App–Guided Mindfulness Meditation in Patients With Insomnia: Mixed Methods Feasibility and Acceptability Pilot Study

Bedtime App–Guided Mindfulness Meditation in Patients With Insomnia: Mixed Methods Feasibility and Acceptability Pilot Study

Mindfulness meditation (MM) may be a promising nonpharmacological treatment for improving sleep quality by reducing bedtime stress and arousal [30], while barriers to adoption and scalability are also issues. Technology-based approaches facilitate remote delivery of mindfulness-based interventions to be more affordable, accessible, and scalable.

Yan Ma, Peter M Wayne, Janet M Mullington, Suzanne Bertisch, Gloria Y Yeh

JMIR Form Res 2025;9:e67366


Smartphone-Based Mindfulness and Mentalization Ecological Momentary Interventions for Common Mental Health Problems: Pilot Randomized Controlled Trial

Smartphone-Based Mindfulness and Mentalization Ecological Momentary Interventions for Common Mental Health Problems: Pilot Randomized Controlled Trial

Mindfulness and mentalization represent 2 psychological constructs with the potential to mitigate the negative impact of perceived EE on individuals experiencing depression and anxiety. Mindfulness-based interventions cultivate a nonjudgmental awareness of one’s present moment experiences, including thoughts and feelings related to perceived criticism or hostility [25].

Ciarán O'Driscoll, Sarah O'Reilly, Agata Julita Jaremba, Tobias Nolte, Madiha Shaikh

JMIR Ment Health 2025;12:e79296


Ecological Momentary Assessment as a Measure of Intervention Change: Evaluation in 4 Digital Mental Health Trials

Ecological Momentary Assessment as a Measure of Intervention Change: Evaluation in 4 Digital Mental Health Trials

At baseline, adolescents and parents completed self-report questionnaires, set up the mindfulness mobile app (Child and Adolescent Research in Emotion [CARE] app) on the adolescent’s mobile device, and learned how to use it. In sample 1, all participants used the same version of the app, which prompted participants to report on mood and rumination and included a mindfulness intervention.

Christian A Webb, Lori M Hilt, Caroline M Swords, Daniel M Bolt, Hadar Fisher, Simon B Goldberg

J Med Internet Res 2025;27:e69297


Mindful Movement Programs in Community and University Preschools: Protocol for a Pilot Randomized Controlled Trial

Mindful Movement Programs in Community and University Preschools: Protocol for a Pilot Randomized Controlled Trial

Using this approach facilitated the reinforcement of learned mindfulness strategies and ensured the consistency of school-home environments to support children’s behavior. By training the teachers and providing calm corner kits, children have more opportunities across settings for SEL. While most school-based mindfulness research has focused on adolescents, findings show limited effects on externalizing behaviors (eg, aggression) and modest impacts on internalizing behaviors (eg, anxiety) [18-20].

Jacinda K Dariotis, Dana A Eldreth, Rachel Jackson-Gordon, Hong Li, Kai-Ning Wang, Chunyuan Xi, Gregory F Lewis, Elizabeth A Shirtcliff

JMIR Res Protoc 2025;14:e75731


Enhancing Engagement, Practice Integration, and Skill Learning in Mobile Technology–Delivered Interventions Using Human Support: Randomized Controlled Trial With Depressed College Students

Enhancing Engagement, Practice Integration, and Skill Learning in Mobile Technology–Delivered Interventions Using Human Support: Randomized Controlled Trial With Depressed College Students

In an exploratory fashion, we examined whether there were differences among the 3 intervention groups on 2 other sets of self-report outcomes: For the second set of outcomes, practice integration, we specifically examined (3) “everyday mindfulness” and the likelihood of engaging in future mindfulness practices, whether (4) using the app, (5) engaging in mindfulness exercises on one’s own, or (6) generally being more mindful in daily life.

Colleen S Conley, Brynn M DeLorenzo, Carol H Gonzales, Ian J Kahrilas, Jennifer Duffecy, Rebecca L Silton

JMIR Form Res 2025;9:e56963


Characteristics Associated With the Use of the Mindfulness Meditation App Headspace in a Large Public Health Deployment: Cross-Sectional Survey Study

Characteristics Associated With the Use of the Mindfulness Meditation App Headspace in a Large Public Health Deployment: Cross-Sectional Survey Study

Examples of digital mental health mediums include internet-based therapy, as well as self-guided platforms such as websites and apps that provide psychoeducation, journaling tools, peer support, and mindfulness meditation. Mindfulness is a state of bringing nonjudgmental attention to the present experience. Mindfulness meditation is a practice that sets aside time to develop mindfulness, and mindfulness mediation apps tend to be some of the most popular and commonly downloaded DMHIs [4].

Judith Borghouts, Elizabeth V Eikey, Cinthia De Leon, Stephen M Schueller, Margaret Schneider, Nicole A Stadnick, Kai Zheng, Dana B Mukamel, Dara H Sorkin

JMIR Form Res 2025;9:e73457


A Virtual Reality–Based Cognitive Defusion Application for Youth Depression and Anxiety: Mixed Methods Experimental Study

A Virtual Reality–Based Cognitive Defusion Application for Youth Depression and Anxiety: Mixed Methods Experimental Study

Toronto Mindfulness Scale (TMS)–State Version [46] is a 13-item scale measuring state mindfulness. Items are presented as statements referring to 2 constructs, decentering and curiosity, which are each scored as subscales. Decentering refers to psychological distance from thoughts, and curiosity refers to appreciation of thoughts with an accepting and curious attitude.

Imogen H Bell, Cassandra Li, Andrew Thompson, Carli Ellinghaus, Shaunagh O’Sullivan, Kate Alexandra Reynolds, Greg Wadley, Yang Liu, Sarah Bendall, John Gleeson, Lucia Valmaggia, Mario Alvarez-Jimenez

JMIR Ment Health 2025;12:e70160