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Development of a Mobile App (iCANSleep) to Treat Insomnia in Cancer Survivors: User-Centered Design Study

Development of a Mobile App (iCANSleep) to Treat Insomnia in Cancer Survivors: User-Centered Design Study

Among the most common challenges of cancer survivorship is insomnia, which limits recovery [4] and quality of life [5]. Cancer survivors are approximately 3 times more likely to experience insomnia than the general population, and this insomnia can persist for up to 10 years after diagnosis [6-9].

Sheila N Garland, Samlau Kutana, Katherine-Ann Piedalue, Rachel Lee, Joshua Rash, Gregory Cerallo

JMIR Cancer 2025;11:e74387


Validating the Efficacy of a Mobile Digital Therapeutic for Insomnia (WELT-I): Randomized Controlled Decentralized Clinical Trial

Validating the Efficacy of a Mobile Digital Therapeutic for Insomnia (WELT-I): Randomized Controlled Decentralized Clinical Trial

To address these challenges, digital therapeutics for insomnia (DTx-Is), which represent a type of digitalized CBT-I, have been developed. Digital therapeutics are defined as evidence-based therapeutic interventions for patients, which are driven by high-quality software programs to prevent, manage, or treat a medical disorder or disease [20]. DTx-Is specifically deliver CBT-Is, which are standardized and effective treatments for insomnia.

Kyung Mee Park, Suonaa Lee, Yujin Lee, Daa Un Moon, Eun Lee

J Med Internet Res 2025;27:e70722


Encouraging General Practitioners to Refer Patients With Insomnia to a Digital Therapeutic (Sleepio): Feasibility Repeated-Measures Intervention Study

Encouraging General Practitioners to Refer Patients With Insomnia to a Digital Therapeutic (Sleepio): Feasibility Repeated-Measures Intervention Study

Sleepio is a digital therapeutic using digital cognitive behavioral therapy for insomnia (CBTi) and has been recommended by the United Kingdom’s National Institute for Health and Care Excellence (NICE) for treating patients with insomnia and insomnia symptoms [10]. The clinical evidence for Sleepio indicates that it is an effective treatment for insomnia and can improve insomnia symptoms and poor sleep [11]. NICE has concluded in-year cost savings over usual insomnia treatments in primary care [10].

Ohoud Alkhaldi, Brian McMillan, John Ainsworth

JMIR Form Res 2025;9:e75359


Effectiveness of Information and Communication Technology–Based Cognitive Behavioral Therapy Using the Smart Sleep App on Insomnia in Older Adults: Randomized Controlled Trial

Effectiveness of Information and Communication Technology–Based Cognitive Behavioral Therapy Using the Smart Sleep App on Insomnia in Older Adults: Randomized Controlled Trial

Insomnia, defined as difficulty with falling asleep or maintaining sleep throughout the night [1], is a prevalent public health issue across a variety of age groups worldwide. This condition is often unrecognized or underreported and is considered a disease with significant economic costs [2]. The prevalence of insomnia increases significantly with age, with studies reporting a chronic insomnia prevalence of 20% to 40% among individuals aged 65 years and older [3].

ChanHee Kim, Yeonhee Lee, Seung-Gul Kang, Seon-Heui Lee

J Med Internet Res 2025;27:e67751


Innovative Digital Cognitive Behavioral Treatment for Insomnia Disorder in Adults (dCBT-i): Framework Development

Innovative Digital Cognitive Behavioral Treatment for Insomnia Disorder in Adults (dCBT-i): Framework Development

Insomnia is a major health complaint, with a prevalence up to 50% in primary care patients undergoing current treatment for either independent insomnia or insomnia comorbid with another disease, posing a risk of worsening comorbid medical conditions without addressing insomnia [1].

Emilie Stern, Severine Brune, Stéphane Mouchabac, Anthony Dubroc, Charles de la Personne, Pierre Alexis Geoffroy

JMIR Hum Factors 2025;12:e70193


Effects of Digital Sleep Interventions on Sleep Among College Students and Young Adults: Systematic Review and Meta-Analysis

Effects of Digital Sleep Interventions on Sleep Among College Students and Young Adults: Systematic Review and Meta-Analysis

College students and young adults aged between 18 and 25 years frequently experience poor sleep quality and insufficient sleep duration [1,2] accompanied by a high prevalence of insomnia. Studies have reported that 18.5% of college students have insomnia, whereas 22.6% of young adults experience difficulty falling asleep; these rates are higher than those observed in the general population [3,4].

Yi-An Lu, Hui-Chen Lin, Pei-Shan Tsai

J Med Internet Res 2025;27:e69657


Efficacy of a Self-Guided Internet Intervention With Optional On-Demand Feedback Versus Digital Psychoeducation on Sleep Hygiene for University Students With Insomnia: Randomized Controlled Trial

Efficacy of a Self-Guided Internet Intervention With Optional On-Demand Feedback Versus Digital Psychoeducation on Sleep Hygiene for University Students With Insomnia: Randomized Controlled Trial

We included university students who were (1) aged ≥18 years, (2) displaying heightened insomnia severity (Insomnia Severity Index [ISI] score ≥10 [42,43]), (3) German-speaking, (4) willing to give informed consent to participate in the study, and (5) had internet access.

Anna-Carlotta Zarski, Karina Bernstein, Harald Baumeister, Dirk Lehr, Stella Wernicke, Ann-Marie Küchler, Fanny Kählke, Kai Spiegelhalder, David Daniel Ebert

J Med Internet Res 2025;27:e58024


Assessment of an App-Based Sleep Program to Improve Sleep Outcomes in a Clinical Insomnia Population: Randomized Controlled Trial

Assessment of an App-Based Sleep Program to Improve Sleep Outcomes in a Clinical Insomnia Population: Randomized Controlled Trial

Insomnia, defined as difficulty initiating or maintaining sleep, is the most common sleep disorder, with 20% of adults reporting occasional insomnia symptoms and 10%-30% experiencing chronic insomnia [10,11]. In addition to its physical and mental health impacts, insomnia has significant societal and economic consequences, including reduced productivity, absenteeism, higher accident rates, increased health care costs, and an overall decline in quality of life [12].

Walter Staiano, Christine Callahan, Michelle Davis, Leah Tanner, Chelsea Coe, Sarah Kunkle, Ulrich Kirk

JMIR Mhealth Uhealth 2025;13:e68665


Search Volume of Insomnia and Suicide as Digital Footprints of Global Mental Health During the COVID-19 Pandemic: 3-Year Infodemiology Study

Search Volume of Insomnia and Suicide as Digital Footprints of Global Mental Health During the COVID-19 Pandemic: 3-Year Infodemiology Study

During the pandemic’s early stages, a marked increase in internet searches for “insomnia” was consistently observed, reflecting shifts in mental health dynamics across several countries [10-13]. Building on this foundation, our study explored the relationship between national COVID-19 death rates and search patterns for “insomnia” and “suicide” during the pandemic’s first year [11].

Sheng-Hsuan Lin, Kuan-Pin Su, Hsiao-Hui Tsou, Pei-Hsuan Hsia, Yu-Hsuan Lin

J Med Internet Res 2025;27:e67646