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This study involves a whole-day visit to the LUMC for each participant and includes the following procedures: a 3 T brain MRI scan of 60 minutes, a 7 T brain MRI scan of 60 minutes, a neuropsychological assessment, and questionnaires on demographics and vascular risk factors. An overview of the study procedures can be found in Figure 1.
JMIR Res Protoc 2025;14:e77681
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Upon categorization of states by these parameters, we chose a selection of at least 1‐3 dashboards per region and territory, based on the inclusion of all categories and upon the dashboard being (1) available for public viewing and (2) fitting the definition of a dashboard, “a visual display of the most important information needed to achieve one or more objectives, consolidated and arranged on a single screen so the information can be monitored at a glance” [5].
JMIR Public Health Surveill 2025;11:e71094
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The DSM-5 explicitly states that for a diagnosis of bipolar mania, there must be an increase in energy or activity in addition to mood changes, marking a significant shift from previous editions where mood changes alone sufficed for diagnosis [10,11].
JMIR Ment Health 2025;12:e78163
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A new urine collection technique (midstream urine collection) for males has been applied since November 21, 2019.
JMIR Form Res 2025;9:e75929
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First, many digital clinical trials fail to enroll participants from a broad range of demographic groups, limiting the generalizability of the effects [45]. This is a common problem across clinical trials [46], and certain trial designs, such as decentralized trials, may help address participation barriers by relying on remote data collection methods [47].
Second, few trials have enrolled participants with a confirmed insomnia diagnosis established through structured clinical interviews.
JMIR Ment Health 2025;12:e84323
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A Pitta-dominant individual is more susceptible to diseases like peptic ulcers, hypertension, and skin disorders [14]. However, a Vata-dominant individual is more prone to musculoskeletal issues like back pain and joint degeneration, and a Kapha-dominant individual faces a higher risk of developing metabolic conditions such as obesity, diabetes, and atherosclerosis [14].
JMIR Res Protoc 2025;14:e81329
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Talkspace [33] is a telemedicine platform of over 5000 licensed therapists across the United States. Clients access the platform through the internet and complete a brief intake with a consulting clinician to identify their presenting problems and treatment history.
JMIR Form Res 2025;9:e75290
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Coupled with the rapid increase in ownership of mobile phones in low- and middle-income countries (LMICs; 90% in Nigeria), digital games provide a compelling format for intervention delivery [29]. A genre of games called serious games is developed specifically for a reason other than pure entertainment (ie, promotion of health behaviors or health outcomes) [30].
JMIR Res Protoc 2025;14:e74199
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Inequities in Pr EP use by race are dire: in 2019, just 8% of Black people in need of Pr EP received a prescription, compared to 60% of White people [8]. Just 3 years later, in 2022, Pr EP uptake only increased 5% for Black people compared to a 34% increase for White people, totaling to 94% of White people who need Pr EP being provided a prescription compared to 13% of Black people [8,9].
JMIR Res Protoc 2025;14:e72283
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Activities were designed specifically for use with a humanoid SAR and a dog SAR. The humanoid SAR acted as a coach and cheerleader, while a computer-based avatar acted as the coach and cheerleader for activities involving the dog SAR. The dog SAR then functioned as an entertainment reward.
JMIR Aging 2025;8:e75288
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