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First, randomized clinical trials demonstrate modest efficacy of tamsulosin and other α1a-blockers for improving LUTS, as well as a large placebo effect [7]. This limits the ability of clinicians to identify true responders to chronic tamsulosin therapy and the degree of symptomatic improvement attributable to tamsulosin alone [7,8].
JMIR Form Res 2021;5(12):e30762
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