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Outcomes of an App-Based Intervention to Target Naming Among Individuals With Poststroke Aphasia: Virtual Randomized Controlled Trial

Outcomes of an App-Based Intervention to Target Naming Among Individuals With Poststroke Aphasia: Virtual Randomized Controlled Trial

Aphasia, an acquired language disorder most commonly caused by stroke, impacts linguistic expression and comprehension in both written and oral modalities. People with aphasia may have impairments in their ability to speak, understand, read, and write. Thus, aphasia can severely limit activities and restrict participation in everyday activities [1].

Esther S Kim, Laura Laird, Carlee Wilson, Steven Stewart, Philip Mildner, Sebastian Möller, Raimund Schatz, Robert P Spang, Jan-Niklas Voigt-Antons, Elizabeth Rochon

JMIR Mhealth Uhealth 2025;13:e67711

Balance Improvement and Fall Risk Reduction in Stroke Survivors After Treatment With a Wearable Home-Use Gait Device: Single-Arm Longitudinal Study With 1-Year Follow-Up

Balance Improvement and Fall Risk Reduction in Stroke Survivors After Treatment With a Wearable Home-Use Gait Device: Single-Arm Longitudinal Study With 1-Year Follow-Up

Falls are a common and serious problem after stroke. In the first year following a stroke, approximately 70% of individuals fall [1-3], and the risk of falls remains substantially elevated throughout the stroke survivor’s lifespan [2]. The physical consequences of falls can be devastating, often leading to hospitalizations, serious injuries, and even death [4].

Brianne Darcy, Lauren Rashford, David Huizenga, Kyle B Reed, Stacy J M Bamberg

JMIR Form Res 2025;9:e67297

Current Landscape and Future Directions Regarding Generative Large Language Models in Stroke Care: Scoping Review

Current Landscape and Future Directions Regarding Generative Large Language Models in Stroke Care: Scoping Review

Stroke represents a leading cause of global morbidity and long-term disability [1], imposing a substantial burden on health care systems through its high incidence and the complex, prolonged care needs of survivors of stroke [2].

XingCe Zhu, Wei Dai, Richard Evans, Xueyu Geng, Aruhan Mu, Zhiyong Liu

JMIR Med Inform 2025;13:e76636

Development of a Customizable Web-Based Dashboard for Remote Blood Pressure Monitoring: Feasibility and Usability Implementation Study

Development of a Customizable Web-Based Dashboard for Remote Blood Pressure Monitoring: Feasibility and Usability Implementation Study

Elevated systolic and diastolic blood pressure (BP) are associated with an increased risk for stroke [1]. An American Heart Association (AHA) Presidential Advisory Committee projected that hypertension prevalence will increase from 51.2% in 2020 to 61.0% in 2050, leading to higher rates of cardiovascular disease and stroke. The committee also projected an increase in total cardiovascular disease by 3.7% [2].

Joshua Wollen, Thuy Nguyen, Charles Coton, Gina DeWildt, Gabretta Cooksey, Audrey Cohen, Nicholas Hoang, Munachi Okpala, Michael Gonzalez, Mengxi Wang, Chigozirim Izeogu, Elmer Bernstam, Charles Green, Sean Savitz, Jose-Miguel Yamal, Anjail Sharrief

JMIR Form Res 2025;9:e62700

Electronic Clinical Decision Support System for Stroke Risk Screening in Patients With Atrial Fibrillation in Mental Health Care: Mixed Methods Study

Electronic Clinical Decision Support System for Stroke Risk Screening in Patients With Atrial Fibrillation in Mental Health Care: Mixed Methods Study

The questionnaire was developed to assess clinicians’ awareness and confidence regarding AF-related stroke prevention. It included a series of statements related to their knowledge of AF guidelines, their confidence in assessing stroke and bleeding risks using the CHA2 DS2-VASc and ORBIT scales, and their confidence in managing patients at risk of stroke. Each statement was rated on a Likert scale, ranging from strongly disagree to strongly agree (Multimedia Appendix 1).

Dina Farran, Hou Wang Cheang, Juliana Onwumere, Mark Ashworth, Fiona Gaughran

JMIR Cardio 2025;9:e66428

Exploring the Time to Onset and Early Predictors of Poststroke Spasticity Combined With Surface Electromyography: Protocol for a Nested Case-Control Study

Exploring the Time to Onset and Early Predictors of Poststroke Spasticity Combined With Surface Electromyography: Protocol for a Nested Case-Control Study

Stroke is currently the leading cause of disability and death in China, with a high incidence, high disability rate, high mortality rate, and high recurrence rate [1]. In China, approximately 3 million new patients with stroke are diagnosed annually, and 70%-80% of stroke survivors experience residual limb paralysis, which prevents them from living independently. Poststroke spasticity (PSS) is the most prevalent of these disabilities [2].

Simeng Song, Shiliang Wang, Shanshan Zeng, Wenqing Wu, Lingying Wu, Xukun Tang, Xiongxing Sun, Dahua Wu, Le Xie

JMIR Res Protoc 2025;14:e65829

An Integrated Virtual Reality–Based Telerehabilitation Platform to Support Recovery and Maintenance of Functional Abilities Among Older Adults: Protocol for a Usability and Acceptability Study

An Integrated Virtual Reality–Based Telerehabilitation Platform to Support Recovery and Maintenance of Functional Abilities Among Older Adults: Protocol for a Usability and Acceptability Study

Notably, stroke is the third leading cause of long-term disability in most countries and can result in paralysis, speech impairment, loss of memory and reasoning ability, coma, or even death [9]. Additionally, acquired brain injuries, such as traumatic brain injury, can lead to similar long-term disabilities, including balance and motor impairments, cognitive complaints related to memory and concentration, and chronic headache [10].

Marco Benadduci, Claudia Franceschetti, Rachele Alessandra Marziali, Sebastian Frese, Peter Stephan Sándor, Valentina Tombolesi, Valentina Bozzi, Lorena Rossi

JMIR Res Protoc 2025;14:e68358

Digital Interventions for Cognitive Dysfunction in Patients With Stroke: Systematic Review and Meta-Analysis

Digital Interventions for Cognitive Dysfunction in Patients With Stroke: Systematic Review and Meta-Analysis

While some studies showed no significant effect of VR in the area of cognitive improvement, for example, a study by Zhang et al [14], which summarized 23 randomized controlled trials (RCTs) by meta-analysis, found that VR had a significant effect on executive and visuospatial functions in stroke patients, whereas the improvement in overall cognitive function did not show statistically significant differences.

Chen Wang, Min Liu

J Med Internet Res 2025;27:e73687

Application of Large Language Models in Stroke Rehabilitation Health Education: 2-Phase Study

Application of Large Language Models in Stroke Rehabilitation Health Education: 2-Phase Study

Stroke is a leading cause of mortality and disability among middle-aged and older adult individuals worldwide. According to the World Health Organization, more than 15 million people experience a stroke annually, resulting in approximately 6 million deaths and leaving millions more with varying degrees of long-term disability [1].

Shiqi Qiang, Haitao Zhang, Yang Liao, Yue Zhang, Yanfen Gu, Yiyan Wang, Zehui Xu, Hui Shi, Nuo Han, Haiping Yu

J Med Internet Res 2025;27:e73226

The Quality and Reliability of Online Videos as an Information Source of Public Health Education for Stroke Prevention in Mainland China: Electronic Media–Based Cross-Sectional Study

The Quality and Reliability of Online Videos as an Information Source of Public Health Education for Stroke Prevention in Mainland China: Electronic Media–Based Cross-Sectional Study

In the pursuit of better combating this growing threat, the primary prevention of first stroke and secondary prevention of recurrent stroke have emerged as critical strategies and are now recognized as essential components of global stroke control [3,4].

Rongguang Ge, Haoyi Dai, Chicheng Gong, Yuhong Xia, Rui Wang, Jiaping Xu, Shoujiang You, Yongjun Cao

JMIR Infodemiology 2025;5:e64891