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Mindful Nonreactivity, Anxiety, Depression, and Perceived Stress as Mediators of the Mindfulness Virtual Community Intervention—Pathways to Enhance Mental Health in University Students: Secondary Evaluation of Two Randomized Controlled Trials With Student Participants

Mindful Nonreactivity, Anxiety, Depression, and Perceived Stress as Mediators of the Mindfulness Virtual Community Intervention—Pathways to Enhance Mental Health in University Students: Secondary Evaluation of Two Randomized Controlled Trials With Student Participants

Perceived stress was evaluated using the Perceived Stress Scale (PSS), a 10-item, 4-point Likert scale (item range: 0‐4, total score: 0‐40) [53]. Quality of life was evaluated by the 16-item, 7-point (item range: 1‐7, total score: 16‐112) Quality of Life Scale (QOLS) [54].

Meysam Pirbaglou, Christo El Morr, Farah Ahmad, Paul Ritvo

JMIR Ment Health 2025;12:e65853

Exploring the Impact of the Caring Contacts Intervention on the Stress and Distress of Veterans and Service Members: Protocol for a Randomized Controlled Trial

Exploring the Impact of the Caring Contacts Intervention on the Stress and Distress of Veterans and Service Members: Protocol for a Randomized Controlled Trial

Traditional pre- and postintervention assessments often fail to account for the nuanced, day-to-day, or even rapid fluctuations in SI, stress, and distress [43]. This study will be the first to use periodic ecological momentary assessment (EMA) during a study of the Caring Contacts intervention to capture how the intervention decreases SI, stress, and distress.

Barbara Wright, Anna Evanson, Cameron Casey, Keyne C Law, Andrew H Rogers, Katherine Anne Comtois

JMIR Res Protoc 2025;14:e72140

Open Source Web Application (HealthTest) for Emotional Health and Wellness Management in University Students: Development and Usability Study

Open Source Web Application (HealthTest) for Emotional Health and Wellness Management in University Students: Development and Usability Study

A 2020 study conducted in Spain revealed that female health care professionals experienced higher levels of anxiety, stress, and depression compared to their male counterparts, with these issues being more prevalent among individuals aged 20 to 37 years [3]. The prevention and treatment of mental health issues are crucial due to their impact on quality of life and daily functioning [4,5].

Lucrecia Llerena, Daisy Nata Castro, Nancy Rodriguez, Donald Silva Sánchez

Online J Public Health Inform 2025;17:e69413

Novel Virtual Reality Intervention for Stress Reduction Among Patients With or at Risk for Cardiovascular Disease: Mixed Methods Pilot Study

Novel Virtual Reality Intervention for Stress Reduction Among Patients With or at Risk for Cardiovascular Disease: Mixed Methods Pilot Study

VR has now demonstrated promise as a treatment modality for anxiety, phobias, depression, autism, and posttraumatic stress disorder as well as a way to aid in meditation [20-29]. Thus, VR is a potentially powerful tool to target stress reduction in patients with CVD.

Katherine E Makaroff, Christopher Van, Vincent Grospe, Lynae Edmunds, Marcella A Calfon-Press, Karol E Watson, Tamara Horwich

JMIR Cardio 2025;9:e66557

Effect of a Family-Centered Empowerment Model–Based Intervention on the Caregiving Capacity and Preparedness of Caregivers of Children With Malignant Neoplasms: Protocol for a Quasi-Experimental Study

Effect of a Family-Centered Empowerment Model–Based Intervention on the Caregiving Capacity and Preparedness of Caregivers of Children With Malignant Neoplasms: Protocol for a Quasi-Experimental Study

Additionally, the study aims to examine the effects of the empowerment intervention on caregivers’ self-efficacy as well as their levels of depression, anxiety, and stress. This study has the following research hypotheses: Statistically significant differences in caregiver preparedness and caregiving capacity will occur after the FCEM intervention program.

Xiaowan Li, Yanhua Yang, Qiurong Chen, JingJing Ma, Feng Lu, Xiaoli Luo

JMIR Res Protoc 2025;14:e73304

Just-in-Time Delivery of Cognitive Behavioral Therapy–Based Exercises: Single-Case Experimental Design With Random Multiple Baselines

Just-in-Time Delivery of Cognitive Behavioral Therapy–Based Exercises: Single-Case Experimental Design With Random Multiple Baselines

Furthermore, our pilot app was designed to offer different exercises according to the detected levels of stress. This tailoring was important because stress has intraindividual, temporal dynamics, and appropriate coping strategies may differ across the levels and types of stress [21,22]. It is not always possible for individuals to make a rational decision on how to cope with their stress.

Takeyuki Oba, Keisuke Takano, Daichi Sugawara, Kenta Kimura

JMIR Form Res 2025;9:e69556

Future Me, a Prospection-Based Chatbot to Promote Mental Well-Being in Youth: Two Exploratory User Experience Studies

Future Me, a Prospection-Based Chatbot to Promote Mental Well-Being in Youth: Two Exploratory User Experience Studies

These explored students’ stress experiences, coping strategies, and expectations from digital mental health tools. Participants discussed their stress management routines, daily stressors, responses to the Perceived Stress Scale (PSS)-10, and attitudes toward digital mental health tools and chatbots. After the first interviews, participants received instructions for using the Future Me chatbot.

Martin Dechant, Eva Lash, Sarah Shokr, Ciarán O'Driscoll

JMIR Form Res 2025;9:e74411

Kissing as a Protective Factor Against Decreased Salivary pH: Protocol for a Randomized Clinical Trial

Kissing as a Protective Factor Against Decreased Salivary pH: Protocol for a Randomized Clinical Trial

Reference 12: Romantic partner embraces reduce cortisol release after acute stress induction in women Reference 13: Kissing in marital and cohabiting relationships: effects on blood lipids, stress, and relationshipstress

Marcelo Armijos Briones, Mariuxi Aguila Gaibor, Andrea Bermúdez Velásquez

JMIR Res Protoc 2025;14:e65253

Feasibility of Digitally Identifying and Minimizing Stressors in Palliative Care Workplaces by Measuring Stress Continuously for Nurses Through Wearable Sensors (DiPa): Protocol for a Prospective Cross-Sectional Study

Feasibility of Digitally Identifying and Minimizing Stressors in Palliative Care Workplaces by Measuring Stress Continuously for Nurses Through Wearable Sensors (DiPa): Protocol for a Prospective Cross-Sectional Study

This serves to regulate stress reactions and prevent exhaustion of stress hormones. Only in chronic stress (eg, when the available resources are insufficient to relieve stress or when the stressor is present over a long period of time), a third phase, “exhaustion phase”, follows, with symptoms of exhaustion and a dangerous weakening of the immunological system [25]. The Di Pa study aims to test the feasibility of measuring and merging subjective and objective stress parameters in palliative care nurses.

Aaron Seehausen, Wencke Chodan, Florian Höpfner, Carolin Schneider, Sabine Felser, Hugo Murua Escobar, Mario Aehnelt, Christian Junghanss

JMIR Res Protoc 2025;14:e63549