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Finally, in bipolar disorder, sleep and activity disturbances persist even during euthymia and are tied to episode onset, severity, and long-term outcomes [31-33].
Despite their promise, existing studies of actigraphy-derived sleep and activity features have often examined narrow diagnostic groups or short, fixed observation windows, limiting generalizability [34,35].
JMIR Form Res 2025;9:e81107
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Wearable activity trackers, especially actigraphs, are unparalleled in their ability to provide naturalistic and cost-effective motion data, making them invaluable for monitoring children’s physical activity and sleep patterns [1,2]. Actigraphy is now widely deployed across research settings, including clinical trials, and is increasingly being integrated into health care settings to obtain objective biomarkers for pediatric activity and sleep [3-8].
J Med Internet Res 2025;27:e79718
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Daily Time in bed (hours), asleep (hours), awake (hours), and time spent in “light” sleep (equivalent of PSGa N1+N2 sleep; % time asleep), “deep” sleep (equivalent of PSG N3 sleep; % time asleep) and rapid-eye-movement (REM) sleep (% time asleep), for the Oura classified main nocturnal sleep (>3h sleep duration). For each participant, single daily measures of overnight sleep measures were obtained.
JMIR Mhealth Uhealth 2025;13:e80213
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During this period, youth respond to these numerous biopsychosocial challenges with increasing personal autonomy, manifesting profound shifts across multiple health behavior patterns, including sleep [1-3], physical activity [4,5], dietary habits [6-8], and substance use [9].
JMIR Res Protoc 2025;14:e70990
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Adequate sleep in both quality and duration is vital for cognitive function and mental health [10], while a balanced diet is essential for maintaining a healthy weight and supporting optimal growth and development [11]. It is important to recognize that, in addition to physical activity, sedentary behavior, sleep, and healthy eating, other lifestyle factors—such as stress management, social engagement, and substance use—also play significant roles in overall health.
J Med Internet Res 2025;27:e69065
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The FM Sleep A to ZZZ Study is a prospective single-center randomized clinical trial with a 3-arm parallel groups design comparing 4 weeks of morning light treatment, sleep stabilization, and TAU in patients with fibromyalgia. The TAU group will be presented to participants as a study of sleep monitoring to minimize group differences in treatment expectations. A sample diagram of the study protocol is shown in Figure 2.
JMIR Res Protoc 2025;14:e75060
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In the domain of sleep, objective monitoring via actigraphy has been applied relatively widely [31-33].
JMIR Res Protoc 2025;14:e71145
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sleep environment, they had self-reported sleep onset latency >20 minutes; (3) speak and understand English; and (4) have a smart device for mobile app installation.
JMIR Form Res 2025;9:e67366
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Leveraging Smart Bed Technology to Detect COVID-19 Symptoms: Case Study
Certain antimicrobial peptides and cytokines act to prolong sleep, and increased sleep during infection is protective [20]. Thus, a possible immunological function of sleep is to support host defense, which has the evolutionary advantage of preparing the immunological response during a period of low metabolic need and quiescence [21].
Conversely, sleep disturbance appears to negatively impact immune function.
JMIR AI 2025;4:e64018
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Moreover, both “bothered” and “depressed” were negatively associated with shorter sleep duration, aligning with previous findings [33]. Intriguingly, longer sleep duration predicted lower numerical ability, perhaps because middle-aged and older individuals, despite extended sleep periods, often experience frequent nocturnal awakenings that compromise sleep quality [34].
JMIR Aging 2025;8:e76210
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