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An Electronic Medical Record–Based Prognostic Model for Inpatient Falls: Development and Internal-External Cross-Validation

An Electronic Medical Record–Based Prognostic Model for Inpatient Falls: Development and Internal-External Cross-Validation

A clinical prediction model is a model that estimates an individual’s probability of a current health condition (diagnostic) or one that may occur in the future (prognostic). These models are usually estimating a probability, or risk, for the given patient and health outcome.

Rex Parsons, Robin Blythe, Susanna Cramb, Ahmad Abdel-Hafez, Steven McPhail

J Med Internet Res 2024;26:e59634

Improving the Prognostic Evaluation Precision of Hospital Outcomes for Heart Failure Using Admission Notes and Clinical Tabular Data: Multimodal Deep Learning Model

Improving the Prognostic Evaluation Precision of Hospital Outcomes for Heart Failure Using Admission Notes and Clinical Tabular Data: Multimodal Deep Learning Model

The analysis identified commonly ubiquitous clinical terms like “in,” “to,” and “with,” which were segregated due to their limited potential in distinguishing prognostic variations. Among the top 20 clinically meaningful indicators vital for mortality prediction, intriguing insights emerged upon clinical interpretation. For instance, “Failure” and “Pain,” the leading predictors, denote prevalent symptoms within ICU care and can mirror disease severity and disability.

Zhenyue Gao, Xiaoli Liu, Yu Kang, Pan Hu, Xiu Zhang, Wei Yan, Muyang Yan, Pengming Yu, Qing Zhang, Wendong Xiao, Zhengbo Zhang

J Med Internet Res 2024;26:e54363

Predictive and Prognostic Biomarkers in Patients With Mycosis Fungoides and Sézary Syndrome (BIO-MUSE): Protocol for a Translational Study

Predictive and Prognostic Biomarkers in Patients With Mycosis Fungoides and Sézary Syndrome (BIO-MUSE): Protocol for a Translational Study

The TNMB stage at diagnosis remains the most important prognostic factor [9,10]. Many patients with early stages of MF have an indolent disease with a 5-year disease-specific survival of 89% to 98% [8,11]. However, approximately 25% of patients with early stages of disease will later progress to advanced stages [4]. Patients with advanced stages of MF have a 5-year disease-specific survival of 18% to 56% associated with treatment failure [8,10]. The 5-year disease-specific survival of SS is 36% [3,8,10].

Emma Belfrage, Sara Ek, Åsa Johansson, Hanna Brauner, Andreas Sonesson, Kristina Drott

JMIR Res Protoc 2024;13:e55723

Comparing the Perspectives of Generative AI, Mental Health Experts, and the General Public on Schizophrenia Recovery: Case Vignette Study

Comparing the Perspectives of Generative AI, Mental Health Experts, and the General Public on Schizophrenia Recovery: Case Vignette Study

Nevertheless, inherent values and presuppositions inevitably shape prognostic assessments [14,15]. The etiology and treatability of psychiatric disorders are framed by 2 opposing philosophical paradigms. Deterministic models, which view mental disorders as fixed biological anomalies, often adopt a pessimistic perspective on full recovery. In contrast, the recovery model approach is rooted in the belief that complete recovery is achievable.

Zohar Elyoseph, Inbar Levkovich

JMIR Ment Health 2024;11:e53043

Development and Validation of a Robust and Interpretable Early Triaging Support System for Patients Hospitalized With COVID-19: Predictive Algorithm Modeling and Interpretation Study

Development and Validation of a Robust and Interpretable Early Triaging Support System for Patients Hospitalized With COVID-19: Predictive Algorithm Modeling and Interpretation Study

Many prognostic models for patients with COVID-19 severity and mortality have been proposed, yet most were reported unsuitable for clinical application by several systematic review studies [9-11]. Most models were either at a high or unclear risk of bias (Wynants et al [10]: 305 out of 310 studies, 98.4%; Buttia et al [11]: 312 out of 314 studies, 99.4%) such that their reported discriminative performances were deemed neither reliable nor generalizable [10,11].

Sangwon Baek, Yeon joo Jeong, Yun-Hyeon Kim, Jin Young Kim, Jin Hwan Kim, Eun Young Kim, Jae-Kwang Lim, Jungok Kim, Zero Kim, Kyunga Kim, Myung Jin Chung

J Med Internet Res 2024;26:e52134

Predicting the 5-Year Risk of Nonalcoholic Fatty Liver Disease Using Machine Learning Models: Prospective Cohort Study

Predicting the 5-Year Risk of Nonalcoholic Fatty Liver Disease Using Machine Learning Models: Prospective Cohort Study

Early screening for effective interventions can help reduce and delay the occurrence of adverse prognostic events related to NAFLD. NAFLD has no specific hepatic biochemical abnormalities or clinical symptoms in its early stages, and it is often detected by imaging during health checks or follow-ups of other diseases [9]. Although liver biopsy remains the gold standard for diagnosing NAFLD as an invasive technique, large-scale clinical application is unlikely [11].

Guoqing Huang, Qiankai Jin, Yushan Mao

J Med Internet Res 2023;25:e46891

Consolidated Reporting Guidelines for Prognostic and Diagnostic Machine Learning Modeling Studies: Development and Validation

Consolidated Reporting Guidelines for Prognostic and Diagnostic Machine Learning Modeling Studies: Development and Validation

Six prognostic or diagnostic ML studies that were published in JMIR AI were identified, and the resulting items were used to assess whether the authors reported the specific details. The perspective of this assessment was as a reviewer and was not intended to score the papers on adherence to our reporting items. This was performed by one of the authors (KEE).

William Klement, Khaled El Emam

J Med Internet Res 2023;25:e48763