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Health Services Usage in Patients Receiving Buprenorphine for Opioid Use Disorder or Long-Term Opioid Therapy for Chronic Pain: Retrospective Cohort Study

Health Services Usage in Patients Receiving Buprenorphine for Opioid Use Disorder or Long-Term Opioid Therapy for Chronic Pain: Retrospective Cohort Study

In the early months of the pandemic, there were increases in emergency usage related to opioids including emergency department (ED) visits for nonfatal opioid overdoses [20] and emergency medical service runs for fatal and nonfatal opioid-related concerns [21]. Disruption in access for patients who use buprenorphine for OUD and patients who use chronic opioid analgesic therapy may have contributed to these issues.

Samuel T Savitz, Maria A Stevens, Bidisha Nath, Gail D'Onofrio, Edward R Melnick, Molly M Jeffery

JMIR Form Res 2025;9:e66596

Challenging the Continued Usefulness of Social Media Recruitment for Surveys of Hidden Populations of People Who Use Opioids

Challenging the Continued Usefulness of Social Media Recruitment for Surveys of Hidden Populations of People Who Use Opioids

The primary barrier to feasibility in internet-based recruitment is access to people who use opioids, given the highly stigmatized nature of drug use [4,5].

Elizabeth D Nesoff, Joseph J Palamar, Qingyue Li, Wenqian Li, Silvia S Martins

J Med Internet Res 2025;27:e63687

Demographics and Use of an Addiction Helpline for Concerned Significant Others: Observational Study

Demographics and Use of an Addiction Helpline for Concerned Significant Others: Observational Study

Primary substances of concern in the Peer Coaching study included cannabis (60%), opioids (15%), and alcohol (7%). This study is the first to present use and engagement data for a nationally available substance use-specific helpline for CSOs. To inform future service design and delivery, this study provides descriptive information on the population who contacts the Partnership’s helpline.

Rachel Chernick, Amanda Sy, Sarah Dauber, Lindsey Vuolo, Bennett Allen, Fred Muench

J Med Internet Res 2025;27:e55621

Public Health Discussions on Social Media: Evaluating Automated Sentiment Analysis Methods

Public Health Discussions on Social Media: Evaluating Automated Sentiment Analysis Methods

Marijuana, for example, can be discussed as a gateway drug (negative sentiment) and also from a harm reduction perspective as a substitute for opioids and other harmful street drugs (positive sentiment). Classifying the data by sentiment enables researchers to explore diverse perspectives of the digital public, potentially leading to health policy insights.

Lisa M Gandy, Lana V Ivanitskaya, Leeza L Bacon, Rodina Bizri-Baryak

JMIR Form Res 2025;9:e57395

Peer Intervention to Link Overdose Survivors to Treatment (PILOT): Protocol for a Multisite, Randomized Controlled Trial Conducted Within the National Institute on Drug Abuse Clinical Trials Network

Peer Intervention to Link Overdose Survivors to Treatment (PILOT): Protocol for a Multisite, Randomized Controlled Trial Conducted Within the National Institute on Drug Abuse Clinical Trials Network

One of the greatest risk factors for a fatal overdose is experiencing a nonfatal overdose involving opioids (NFOO) in the previous year. Indeed, 6% to 10% of individuals who experience an NFOO die in the following year [3-5]. Survivors of NFOOs most commonly die of another overdose (67%) [3], with the highest risk period being the month following NFOO [5]. Interventions that reduce the risk of a subsequent overdose among NFOO survivors would substantially impact premature mortality.

Carrie Papa, Erin A McClure, Jenna McCauley, Louise Haynes, Timothy Matheson, Richard Jones, Lindsey Jennings, Tricia Lawdahl, Ralph Ward, Kathleen Brady, Kelly Stephenson Barth

JMIR Res Protoc 2024;13:e60277

Design and Implementation of an Opioid Scorecard for Hospital System–Wide Peer Comparison of Opioid Prescribing Habits: Observational Study

Design and Implementation of an Opioid Scorecard for Hospital System–Wide Peer Comparison of Opioid Prescribing Habits: Observational Study

The United States is in an opioid epidemic originally partially fueled by legitimate but inappropriate rates of opioid prescriptions [1-4], with additional waves associated with nonprescription opioids [5]. Reducing inappropriate opioid prescribing by health care providers is a key element of mitigating the risk of long-term opioid use and potential dependence for patients [6-10].

Benjamin Heritier Slovis, Soonyip Huang, Melanie McArthur, Cara Martino, Tasia Beers, Meghan Labella, Jeffrey M Riggio, Edmund deAzevedo Pribitkin

JMIR Hum Factors 2024;11:e44662

The Association of Broadband Internet Use With Drug Overdose Mortality Rates in the United States: Cross-Sectional Analysis

The Association of Broadband Internet Use With Drug Overdose Mortality Rates in the United States: Cross-Sectional Analysis

Opioids, either obtained illicitly or as a prescription, accounted for approximately 75% of the total drug overdose deaths in 2020 [1,2]. Recent numbers suggest an acceleration of both drug and opioid overdose deaths during the COVID-19 pandemic, with the United States experiencing the largest number of drug overdose deaths during this period (93,300 deaths) compared to that reported in any given year within the last 2 decades.

Ioannis Karakis, Genti Kostandini, Konstantinos Tsamakis, Velma Zahirovic-Herbert

Online J Public Health Inform 2024;16:e52686

Users' Acceptability and Perceived Efficacy of mHealth for Opioid Use Disorder: Scoping Review

Users' Acceptability and Perceived Efficacy of mHealth for Opioid Use Disorder: Scoping Review

Excess levels of opioids may lead to respiratory depression and cardiopulmonary failure, resulting in loss of consciousness and death [3,4]. It is treated with naloxone, an antagonist that prevents opioid-related fatalities [5,6]. Thus, it is essential to find ways to manage opioid use disorder (OUD) and prevent overdose. A study reviewing smartphone apps that were commercially available until 2019 found that there was a lack of evidence on their ability to be useful for monitoring OUD [7].

Lynnette Nathalie Lyzwinski, Mohamed Elgendi, Carlo Menon

JMIR Mhealth Uhealth 2024;12:e49751

The Feasibility of Using the National PulsePoint Cardiopulmonary Resuscitation Responder Network to Facilitate Overdose Education and Naloxone Distribution: Protocol for a Randomized Controlled Trial

The Feasibility of Using the National PulsePoint Cardiopulmonary Resuscitation Responder Network to Facilitate Overdose Education and Naloxone Distribution: Protocol for a Randomized Controlled Trial

Even before the formal declaration of a public health emergency around opioids, the Department of Health and Human Services included expanded use and distribution of naloxone in its 3 priority areas to address the overdose epidemic [8].

Jon Agley, Cris Henderson, Dong-Chul Seo, Maria Parker, Lilian Golzarri-Arroyo, Stephanie Dickinson, David Tidd

JMIR Res Protoc 2024;13:e57280