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Evaluation of the Feasibility of Transfusing Leukocyte Depletion Filter–Processed Intraoperative Cell Salvage Blood in Metastatic Spine Tumor Surgery: Protocol for a Non–Randomized Study

Evaluation of the Feasibility of Transfusing Leukocyte Depletion Filter–Processed Intraoperative Cell Salvage Blood in Metastatic Spine Tumor Surgery: Protocol for a Non–Randomized Study

The skeletal system is the third most common site of metastases, and cadaveric studies show that spinal metastases can be found in 30% to 90% of patients who die of cancer [1,2]. Surgery for metastatic spine disease (MSD) is complex, often requiring wide resection and extensive reconstruction leading to significant blood loss [1,2].

Naresh Kumar, Si Jian Hui, Renick Lee, Sahil Athia, Joel Yong Hao Tan, Jonathan Jiong Hao Tan

JMIR Res Protoc 2025;14:e54609