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Telemedicine Prescribing by US Mental Health Care Providers: National Cross-Sectional Survey

Telemedicine Prescribing by US Mental Health Care Providers: National Cross-Sectional Survey

Examples of schedule III medications include buprenorphine (Suboxone), testosterone, and ketamine. It is plausible that nonpsychiatry specialists, unlikely to prescribe buprenorphine or ketamine in their practices, may have based their response on other medications within schedule III, medications with which they are more familiar. All addiction psychiatry or medicine specialists indicated a high level of comfort in prescribing schedule III medications.

Mollie R Cummins, Julia Ivanova, Hiral Soni, Zoe Robbins, Brian E Bunnell, Esteban López, Brandon M Welch

JMIR Form Res 2025;9:e63251

Preliminary Evaluation of a Web-Based International Journal Club for Ketamine in Psychiatric Disorders: Cross-Sectional Survey Study

Preliminary Evaluation of a Web-Based International Journal Club for Ketamine in Psychiatric Disorders: Cross-Sectional Survey Study

In the wake of the COVID-19 pandemic, a group of academic clinicians at the University of Oxford and psychiatry trainees in the United Kingdom recognized the need for a platform to share knowledge about ketamine and related compounds in psychiatry. Their ultimate goal was to connect researchers and clinical practitioners. This initiative led to the establishment of the Ketamine and Related Compounds International Journal Club (KIJC), subsequently referred to as the journal club.

Jacek R Lindner, Ashkan Ebrahimi, Julian F Kochanowicz, Justyna Szczupak, Timothy Paris, Ahmed Abdelsamie, Sagar V Parikh, Rupert McShane, Sara Costi

JMIR Med Educ 2023;9:e46158

Efficacy and Tolerability of Two Novel “Standard of Care” Treatments—Intranasal Esketamine Versus Intravenous Ketamine—for Treatment-Resistant Depression in Naturalistic Clinical Practice: Protocol for a Pilot Observational Study

Efficacy and Tolerability of Two Novel “Standard of Care” Treatments—Intranasal Esketamine Versus Intravenous Ketamine—for Treatment-Resistant Depression in Naturalistic Clinical Practice: Protocol for a Pilot Observational Study

Racemic ketamine and its enantiomer esketamine have been studied as novel alternatives for treatment-resistant depression (TRD) in major depressive disorder (MDD) and bipolar depression [1-3]. Studies with intravenous (IV) racemic ketamine have demonstrated rapid and potent reduction of depressive symptoms after the administration of a single subanesthetic dose (response rate=3.01, 95% CI 1.96-4.62; remission rate=3.70, 95% CI 2.28-6.01) [4-8].

Gilmar Gutierrez, Joshua Rosenblat, Emily Hawken, Jennifer Swainson, Gustavo Vazquez

JMIR Res Protoc 2022;11(5):e34711

The Safety, Clinical, and Neurophysiological Effects of Intranasal Ketamine in Patients Who Do Not Respond to Electroconvulsive Therapy: Protocol for a Pilot, Open-Label Clinical Trial

The Safety, Clinical, and Neurophysiological Effects of Intranasal Ketamine in Patients Who Do Not Respond to Electroconvulsive Therapy: Protocol for a Pilot, Open-Label Clinical Trial

It has also been reported that the route of administration of ketamine can influence the clinical antidepressant effects of treatment owing to its extensive first-pass metabolism; specifically, the highest bioavailability of ketamine is achieved via intravenous infusion, while oral administration yields the lowest bioavailability [13].

Yuliya Knyahnytska, Reza Zomorrodi, Tyler Kaster, Daphne Voineskos, Alisson Trevizol, Daniel Blumberger

JMIR Res Protoc 2022;11(1):e30163

Combining Ketamine and Internet-Based Cognitive Behavioral Therapy for the Treatment of Posttraumatic Stress Disorder: Protocol for a Randomized Controlled Trial

Combining Ketamine and Internet-Based Cognitive Behavioral Therapy for the Treatment of Posttraumatic Stress Disorder: Protocol for a Randomized Controlled Trial

The objective of this study is to provide a greater reduction in symptoms with a combination treatment of ketamine and electronically delivered cognitive behavioral therapy (e-CBT) as compared with currently available therapeutic options for treatment-resistant patients. Ketamine offers a promising research avenue for treating refractory PTSD.

Aaron Emile Philipp-Muller, Taras Reshetukha, Gustavo Vazquez, Roumen Milev, Dawn Armstrong, Jasleen Jagayat, Nazanin Alavi

JMIR Res Protoc 2021;10(7):e30334