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To address the challenges of modeling rare diseases in SCs, we conducted an exploratory pilot study with the following objectives: (1) to enhance the representation of Fabry disease within an SC by incorporating insights from guided interviews with experts.
JMIR AI 2025;4:e55001
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We purposively chose interviews over a literature review because the current DHI literature primarily provides superficial descriptions of the adaptation processes. Instead, interviewing experts allows for a deeper and more nuanced understanding of current practice, challenges, and gaps, and provides experience-based recommendations. Interviews were concluded once we reached thematic saturation.
JMIR Mhealth Uhealth 2025;13:e59965
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The underlying interviews and corresponding transcripts, have already been examined for existing problems and barriers in the context of AI-based CDSS from the perspective of experts.
There is some evidence of problems and barriers, but as the field of AI-based CDSS is relatively new, little is known about how to optimize its use. Therefore, qualitative research in the form of expert interviews was conducted to approach the topic in an explorative way.
JMIR Med Inform 2025;13:e69688
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The mixed methods approach, including financial modeling, surveys, and interviews, lends credibility to the findings, while the focus on sustained-release dosage forms highlights a specific and practical application. The paper is well structured and contributes meaningfully to the discussion on enhancing local pharmaceutical capabilities. However, there are areas where clarity, presentation, and depth can be improved to strengthen its impact.
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JMIRx Med 2025;6:e77627
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We conducted in-depth interviews with 15 participants, ensuring data saturation in accordance with qualitative research methodology. Among them, 5 were local company owners specializing in IMD development, as they provided firsthand insights into industry challenges and opportunities. The remaining participants included experts from various sectors of IMD advancement, such as regulatory affairs, financial modeling, and clinical development, ensuring a comprehensive and diverse perspective.
JMIRx Med 2025;6:e77623
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The qualitative component included a literature review, surveys, and expert interviews, while the quantitative component focused on financial modeling and analysis.
A comprehensive review of existing IMD dosage forms, manufacturing processes, cost structures, regulatory requirements, and market trends was conducted using Pub Med, Scopus, and industry reports. This review served as input for the development of the financial model and interview guide.
JMIRx Med 2025;6:e65978
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The semistructured interviews were conducted over the phone. The interviews were conducted by study researchers (SC, NL, and BH; see the following section on researcher characteristics). The duration of the interviews ranged between 15 and 42 minutes. The interview guides were developed using the Clinical Performance Feedback Intervention Theory framework [34] and were pilot-tested during earlier optimization work on the FHT cancer module [27].
JMIR Cancer 2025;11:e65461
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An Exergames Program for Adolescents With Type 1 Diabetes: Qualitative Study of Acceptability
To understand the acceptability of Exer T1 D, we conducted semistructured interviews with all enrollees to complement quantitative evaluations reported elsewhere, in which participant acceptability of this intervention was demonstrated with results from survey data [19].
JMIR Diabetes 2025;10:e65665
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Parents’ Motivations for Calling an Out-of-Hours Helpline: Qualitative Study
Included parents for interviews. MH1813: Medical Helpline 1813; RCT: randomized controlled trial.
Parents unable to participate in a telephone interview or calling regarding an injury were asked to self-exclude, as the videos did not cover injuries, and they may have differed in their motivations for calling MH1813. A total of 6 interviews appeared to be related to injuries of the child.
J Med Internet Res 2025;27:e66780
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