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Opportunities and Challenges for Designing in Connected Health: Insights From an Expert Workshop

Opportunities and Challenges for Designing in Connected Health: Insights From an Expert Workshop

Implementing resource-based architectures, supported by frameworks such as Fast Healthcare Interoperability Resources (FHIR), ensures that systems can scale effectively to handle increasing data volumes. Additionally, these infrastructures provide opportunities for integrating tools such as predictive analytics and decision-support systems, further enhancing their utility. However, the success of digital infrastructures relies on adherence to standards for data security, privacy, and interoperability.

Shweta Premanandan, Awais Ahmad, Alex Jaranka, Ece Üreten, Eunji Lee, Jennifer Gross, Åsa Cajander, Sofia Ouhbi, Marta Lárusdóttir, Owen Eriksson, Sten-Erik Öhlund

J Med Internet Res 2025;27:e72446


DermaDashboard: Bridging the Gap Between FHIR Standards and Clinical Usability

DermaDashboard: Bridging the Gap Between FHIR Standards and Clinical Usability

In recent years, health care systems have rapidly embraced digitalization to enhance patient care, streamline clinical workflows, and improve interoperability of health information [1-4]. At the heart of this transformation is the widespread adoption of electronic health records (EHRs) [5], which, on a broader scale, support the secondary use of data beyond clinical aspects, such as quality control, safety measurements, payments, certification, and research [6,7].

Katarzyna Borys, Eva Maria Hartmann, Ahmad Idrissi-Yaghir, Elisabeth Livingstone, Georg Lodde, Cynthia Sabrina Schmidt, Philipp Winnekens, Christoph M Friedrich, René Hosch, Felix Nensa

JMIR Cancer 2025;11:e73691


Clinical Trial Schedule of Activities Specification Using Fast Healthcare Interoperability Resources Definitional Resources: Mixed Methods Study

Clinical Trial Schedule of Activities Specification Using Fast Healthcare Interoperability Resources Definitional Resources: Mixed Methods Study

Healthcare interoperability standards such as the Fast Healthcare Interoperability Resources (FHIR) [1] are providing new methodological approaches for the collection, collation, and confirmation of clinical research data for both observational studies and trials supporting product regulatory submissions [2-4]. To be successful, clinical research studies require that (1) the correct data are available to answer the research question and (2) these data are collected at the correct times.

Andrew Richardson, Patrick Genyn

JMIR Med Inform 2025;13:e71430


Digital Catalysts for Noncommunicable Disease Prevention Serious Games and Gamified Applications: Framework Design Study

Digital Catalysts for Noncommunicable Disease Prevention Serious Games and Gamified Applications: Framework Design Study

This observation shows the importance of well-made implementation guides (IGs) focusing on well-defined medical areas, such as NCD prevention, and using current interoperability standards. The framework suggests using standards, but no IGs or interoperability profiles are provided. Yusoff et al [23] developed a conceptual framework for serious learning games. It combines learning and pedagogy theory with gaming requirements.

Christoph Aigner, René Baranyi, Thomas Grechenig

JMIR Serious Games 2025;13:e69246


Digital Capability, Open-Source Use, and Interoperability Standards Within the National Health Service in England: Survey of Health Care Trusts

Digital Capability, Open-Source Use, and Interoperability Standards Within the National Health Service in England: Survey of Health Care Trusts

Within this strategy, the UK Health Security Agency (UKHSA) aims to prioritize FAIR (findability, accessibility, interoperability, and reusability) principles [11]. In the context of FAIR, interoperability is defined as “the data need to interoperate with applications or workflows for analysis, storage, and processing.”

Matthew Russell Bennion, Ross Spencer, Roger K Moore, Richard Kenyon

JMIR Hum Factors 2025;12:e66398


A Unique Way to Axe the Fax Through Using Business Automation Workflow to Expedite eReferral Adoption, Bridging eReferral, and Fax: Proof-of-Concept Study

A Unique Way to Axe the Fax Through Using Business Automation Workflow to Expedite eReferral Adoption, Bridging eReferral, and Fax: Proof-of-Concept Study

Through integration with the e Referral platform using Health Level Seven (HL7) Fast Healthcare Interoperability Resources (FHIR), the BAW platform will receive the pdf package, including the referral details and the required fax number [14-16]. The BAW platform will then automate the process following a predefined workflow and deliver information to the fax-based receiving clinician through the second integration with the fax service platform.

Zhigang Tian, Kayla Wierts, Lirije Hyseni, Beth Gerritsen, Kim Lynch, Russell Buchanan, Mohamed Alarakhia

JMIR Med Inform 2025;13:e62983


Proposal for Using AI to Assess Clinical Data Integrity and Generate Metadata: Algorithm Development and Validation

Proposal for Using AI to Assess Clinical Data Integrity and Generate Metadata: Algorithm Development and Validation

Several studies emphasized the necessity of standard terminologies and ontologies to enhance data consistency and interoperability. In addition, multiple sources explored different machine learning techniques, such as supervised and unsupervised learning approaches, to detect and mitigate issues related to incomplete or inconsistent data. Key insights from the literature were incorporated into the introduction and methodology sections, providing a solid theoretical foundation for this study.

Caroline Bönisch, Christian Schmidt, Dorothea Kesztyüs, Hans A Kestler, Tibor Kesztyüs

JMIR Med Inform 2025;13:e60204


Detecting Redundant Health Survey Questions by Using Language-Agnostic Bidirectional Encoder Representations From Transformers Sentence Embedding: Algorithm Development Study

Detecting Redundant Health Survey Questions by Using Language-Agnostic Bidirectional Encoder Representations From Transformers Sentence Embedding: Algorithm Development Study

Both PROMIS and the CDE repository are essential for enhancing the interoperability of health data. In practice, the deployment of PGHD acquisition applications requires that survey questions be drawn from these established standardized resources. Data collected using questions outside of these resources still require additional efforts to achieve standardization.

Sunghoon Kang, Hyewon Park, Ricky Taira, Hyeoneui Kim

JMIR Med Inform 2025;13:e71687


Enhancing Interoperability for a Sustainable, Patient-Centric Health Care Value Chain: Systematic Review for Taxonomy Development

Enhancing Interoperability for a Sustainable, Patient-Centric Health Care Value Chain: Systematic Review for Taxonomy Development

Previous reviews on interoperability have not focused on specific industries such as health care, nor have they consistently provided structured classifications. One review addressed user model interoperability but lacked a systematic approach [17]. Another study examined evaluation models of interoperability, categorizing 12 models across 4 granularity levels [10]. While this study mentioned interoperability attributes, these were not developed through a systematic procedure [10].

Carlos Antonio Marino, Claudia Diaz Paz

J Med Internet Res 2025;27:e69465


Fast Healthcare Interoperability Resources (FHIR)–Based Interoperability Design in Indonesia: Content Analysis of Developer Hub’s Social Networking Service

Fast Healthcare Interoperability Resources (FHIR)–Based Interoperability Design in Indonesia: Content Analysis of Developer Hub’s Social Networking Service

To facilitate this exchange, HIE requires a data exchange or data interoperability framework that provides a standardized format for transferring health data [2]. One of the organizations that provides such interoperability frameworks is Health Level Seven (HL7) [3]. HL7 is a nonprofit organization that develops interoperability frameworks, such as HL7 FHIR (Fast Healthcare Interoperability Resources). It is a newer standard that provides a modern and flexible approach to exchanging health information.

Lukman Heryawan, Yukiko Mori, Goshiro Yamamoto, Naoto Kume, Lutfan Lazuardi, Anis Fuad, Tomohiro Kuroda

JMIR Form Res 2025;9:e51270