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Skip search results from other journals and go to results- 8 JMIR Diabetes
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These signals include ghrelin, cholecystokinin, insulin, glucose-dependent insulinotropic polypeptide, secretin, peptide tyrosine tyrosine, insulin-like peptide 5, neurotensin, substance P, and GLP-1. The hormones relay information to the brain about acute changes in energy needs via stimulation of the vagus nerve, with some signals crossing the blood-brain barrier to bind to receptors in neural circuits that impact feeding [25].
JMIR Res Protoc 2025;14:e66554
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Each prediabetes phenotype exhibits distinct pathophysiological abnormalities [5-7]. i-IFG is marked by impaired early-phase insulin secretion and hepatic insulin resistance. Conversely, i-IGT involves impairments in both early- and late-phase insulin secretion and skeletal muscle insulin resistance [5,7].
JMIR Res Protoc 2025;14:e59842
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In an earlier study, we demonstrated the ability of a web-based blood glucose monitoring system to optimize insulin dosages for patients receiving a basal-plus or basal-bolus insulin regimen. Importantly, glycemic control improved without increasing hypoglycemia rates [18]. However, although this approach reduced the need for face-to-face visits for insulin titration, physicians still need to review a large amount of SMBG data before recommending any insulin dose adjustment.
JMIR Form Res 2025;9:e68914
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We have previously shown that individuals who carry this allele have a multiplicative risk of developing MASLD if they also have insulin resistance.
JMIR Form Res 2025;9:e60051
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Several other large observational studies reported the association of insulin with increased risk of CVD-related outcomes, including comparisons across doses of insulin, of insulin monotherapy versus insulin plus metformin, and of insulin versus novel therapies (DPP-4 Is or SGLT2 Is grouped together) [8]. These studies did not cover all head-to-head comparisons between insulin and alternative therapies.
JMIR Diabetes 2024;9:e58137
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Last, the LUMCCare was further developed to also accommodate insulin registration and other activities than steps (eg, cycling or swimming).
Outcomes of patient panel.
JMIR Hum Factors 2024;11:e45055
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Nutritional education, with systematic assessments of carbohydrate intake and the use of the insulin-to-carbohydrate ratio, has allowed for optimizing insulin dosage [2]. The basal-bolus scheme with multiple-dose insulin injections, continuous subcutaneous insulin infusion, and multiple capillary blood glucose measurements allow for better metabolic control. For this, adequate and continued diabetes education for patients and families is required [3].
JMIR Serious Games 2024;12:e49478
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These actions result in increased vascular blood flow and shear stress via gravitational pull and the skeletal muscle pump, thus increasing venous return, decreasing blood pooling in the lower limbs, and activating contraction- and insulin-mediated glucose uptake pathways [21].
JMIR Res Protoc 2023;12:e45133
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Persons with diabetes with or without an insulin pump were included. The Montreal Cognitive Assessment (Mo CA) was used to screen participants [28]. The Mo CA was performed as the incidence of dementia in persons with diabetes is more than 2 times that of people without diabetes [29]. Thus, we wanted to avoid the inclusion of individuals with moderate to severe dementia, as these individuals might lack the ability to participate in sessions targeting communication patterns.
JMIR Nursing 2023;6:e46627
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Data on technology use were collected, including if the child had ever used an insulin pump or CGM device, if the child was currently using an insulin pump or CGM device, and the dates the insulin pump or CGM device were used. Participant selection and data abstraction were both performed in 2019.
JMIR Diabetes 2023;8:e45890
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