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Assessment of an App-Based Sleep Program to Improve Sleep Outcomes in a Clinical Insomnia Population: Randomized Controlled Trial

Assessment of an App-Based Sleep Program to Improve Sleep Outcomes in a Clinical Insomnia Population: Randomized Controlled Trial

Insomnia, defined as difficulty initiating or maintaining sleep, is the most common sleep disorder, with 20% of adults reporting occasional insomnia symptoms and 10%-30% experiencing chronic insomnia [10,11]. In addition to its physical and mental health impacts, insomnia has significant societal and economic consequences, including reduced productivity, absenteeism, higher accident rates, increased health care costs, and an overall decline in quality of life [12].

Walter Staiano, Christine Callahan, Michelle Davis, Leah Tanner, Chelsea Coe, Sarah Kunkle, Ulrich Kirk

JMIR Mhealth Uhealth 2025;13:e68665

Search Volume of Insomnia and Suicide as Digital Footprints of Global Mental Health During the COVID-19 Pandemic: 3-Year Infodemiology Study

Search Volume of Insomnia and Suicide as Digital Footprints of Global Mental Health During the COVID-19 Pandemic: 3-Year Infodemiology Study

During the pandemic’s early stages, a marked increase in internet searches for “insomnia” was consistently observed, reflecting shifts in mental health dynamics across several countries [10-13]. Building on this foundation, our study explored the relationship between national COVID-19 death rates and search patterns for “insomnia” and “suicide” during the pandemic’s first year [11].

Sheng-Hsuan Lin, Kuan-Pin Su, Hsiao-Hui Tsou, Pei-Hsuan Hsia, Yu-Hsuan Lin

J Med Internet Res 2025;27:e67646

Digital Cognitive Behavioral Therapy–Based Treatment for Insomnia, Nightmares, and Posttraumatic Stress Disorder Symptoms in Survivors of Wildfires: Pilot Randomized Feasibility Trial

Digital Cognitive Behavioral Therapy–Based Treatment for Insomnia, Nightmares, and Posttraumatic Stress Disorder Symptoms in Survivors of Wildfires: Pilot Randomized Feasibility Trial

A study examining sleep disturbances and PTSD in survivors of wildfires revealed that approximately 49.2% (n=126) experienced symptoms of insomnia, 28.7% experienced nightmares, and 77.9% reported PTSD symptoms [12]. Studies suggest that cognitive behavioral therapy for insomnia (CBTi); cognitive behavioral therapy (CBT) for PTSD; and exposure, relaxation, and rescripting therapy (ERRT) for nightmares are effective treatments for insomnia, nightmares, and other trauma symptoms [13-18].

Fadia Isaac, Britt Klein, Huy Nguyen, Shaun Watson, Gerard A Kennedy

JMIR Hum Factors 2025;12:e65228

Development of a Voice-Activated Virtual Assistant to Improve Insomnia Among Young Adult Cancer Survivors: Mixed Methods Feasibility and Acceptability Study

Development of a Voice-Activated Virtual Assistant to Improve Insomnia Among Young Adult Cancer Survivors: Mixed Methods Feasibility and Acceptability Study

Insomnia, characterized by the struggle to initiate or maintain sleep or the experience of nonrestorative sleep, brings along symptoms that hinder daily functioning, such as weariness, concentration difficulties, and mood disruptions [1]. Among the estimated 650,000 young adult cancer survivors (YACS, ages 18-39 years old) in the United States, up to 75% are grappling with insomnia symptoms, with nearly 30% likely to experience insomnia disorder [2-8].

Hunter Groninger, Hannah Arem, Lylian Ayangma, Lisa Gong, Eric Zhou, Daniel Greenberg

JMIR Form Res 2025;9:e64869

Diaphragmatic Breathing Interfaces to Promote Relaxation for Mitigating Insomnia: Pilot Study

Diaphragmatic Breathing Interfaces to Promote Relaxation for Mitigating Insomnia: Pilot Study

Insomnia is an increasingly severe issue, with approximately 30% of the population experiencing related symptoms [1]. It is characterized by difficulty in falling asleep, maintaining sleep, or waking up too early and being unable to return to sleep for at least 3 nights a week. This definition is based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria. Acute insomnia lasts for 1 month, while chronic insomnia persists for over 3 months [2].

Yi-Jen Lai, Hsiao-Yean Chiu, Ko-Chiu Wu, Chun-Wei Chang

JMIR Serious Games 2025;13:e67000

Efficacy and Safety of Acupuncture for Post–COVID-19 Insomnia: Protocol for a Systematic Review and Meta-Analysis

Efficacy and Safety of Acupuncture for Post–COVID-19 Insomnia: Protocol for a Systematic Review and Meta-Analysis

Studies indicate that insomnia has a high prevalence, impacting roughly 20% to 35% of the general population [10-13], and this rate is even higher among health care workers and patients with COVID-19, reaching up to 75% [8]. Substantial evidence indicates that post–COVID-19 insomnia (PCI) frequently persists over the long term [14-17], leading to serious health issues such as increased depression, prolonged work absences, and a heightened risk of hypertension [15,18,19].

Yadi Li, Jianlong Zhou, Zheng Wei, Lizhu Liang, Hualing Xu, Caihong Lv, Gang Liu, Wenlin Li, Xin Wu, Yunhui Xiao, Kejimu Sunzi

JMIR Res Protoc 2025;14:e69417

Relative Preference for In-Person, Telehealth, Digital, and Pharmacologic Mental Health Care After the COVID-19 Pandemic: Cross-Sectional Questionnaire Study

Relative Preference for In-Person, Telehealth, Digital, and Pharmacologic Mental Health Care After the COVID-19 Pandemic: Cross-Sectional Questionnaire Study

Then, participants read 2 vignettes and ranked mental health treatment preference options pertaining to each diagnosis presented in the vignette, with the following question: “Imagine that you have symptoms of [anxiety/insomnia] like [name of the person in the vignette] and want to seek therapy for these symptoms, please rank order the following imagining that you will be interested in seeking treatment for anxiety/insomnia at a later point.”

E Marie Parsons, Zoë G Figueroa, Michele Hiserodt, Talea Cornelius, Michael W Otto

J Med Internet Res 2025;27:e54608

Effectiveness of Cognitive Behavioral Therapy Provided Through a Web Application for Subthreshold Depression, Subthreshold Insomnia, and Subthreshold Panic: Open-Labeled 6-Arm Randomized Clinical Trial Pilot Study

Effectiveness of Cognitive Behavioral Therapy Provided Through a Web Application for Subthreshold Depression, Subthreshold Insomnia, and Subthreshold Panic: Open-Labeled 6-Arm Randomized Clinical Trial Pilot Study

Furthermore, insomnia symptoms are closely associated with SD and subthreshold anxiety, and prevention programs for subthreshold insomnia (SI) have been reported to not only decrease depressive symptoms but also improve insomnia [11]. Namely, when considering primary care for subthreshold symptoms, overlapping symptoms also need to be considered; as a result, the treatment for specific subthreshold symptoms should also have the potential to cover a wide range of subthreshold symptoms.

Kayoko Taguchi, Mirai Miyoshi, Yoichi Seki, Shiori Baba, Eiji Shimizu

JMIR Form Res 2025;9:e63139

Exploring the Psychological and Physiological Insights Through Digital Phenotyping by Analyzing the Discrepancies Between Subjective Insomnia Severity and Activity-Based Objective Sleep Measures: Observational Cohort Study

Exploring the Psychological and Physiological Insights Through Digital Phenotyping by Analyzing the Discrepancies Between Subjective Insomnia Severity and Activity-Based Objective Sleep Measures: Observational Cohort Study

The participants included both individuals with and without insomnia aged 19-70 years with the following inclusion criteria: more than 3 days a week of subjective insomnia symptoms during the past 3 months and an ISI score greater than 15 for the insomnia group, and fewer than 3 days a week of subjective insomnia symptoms during the past 3 months and an ISI score less than 8 for the no insomnia group.

Ji Won Yeom, Hyungju Kim, Seung Pil Pack, Heon-Jeong Lee, Taesu Cheong, Chul-Hyun Cho

JMIR Ment Health 2025;12:e67478

Determinants of Dropout From a Virtual Agent–Based App for Insomnia Management in a Self-Selected Sample of Users With Insomnia Symptoms: Longitudinal Study

Determinants of Dropout From a Virtual Agent–Based App for Insomnia Management in a Self-Selected Sample of Users With Insomnia Symptoms: Longitudinal Study

Chronic insomnia is a major global health concern owing to its high prevalence and its negative impact on mental and physical health [1,2]. The usual approach to treat chronic insomnia includes the prescription of medication, such as nonbenzodiazepine hypnotics [3-5]. Nonpharmacological approaches, such as cognitive behavioral therapy for insomnia (CBT-I), whose goal is to restructure a person’s sleeping behavior, is an evidence-based psychotherapy that has been shown to treat this condition effectively.

María Montserrat Sanchez Ortuño, Florian Pecune, Julien Coelho, Jean Arthur Micoulaud-Franchi, Nathalie Salles, Marc Auriacombe, Fuschia Serre, Yannick Levavasseur, Etienne De Sevin, Patricia Sagaspe, Pierre Philip

JMIR Ment Health 2025;12:e51022