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- 74 Journal of Medical Internet Research
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Twenty years of research associates OSA and hypertension in a dose-dependent manner, with OSA predicting the development of new-onset hypertension [9]. In addition to hypertension, OSA is associated with atrial fibrillation, coronary heart disease, stroke, and increased mortality [10-13]. Second, hypertension is a well-known major risk factor for the development of CVD and carries substantial importance for cardiovascular-related outcomes.
J Med Internet Res 2025;27:e77641
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Hypertension has been diagnosed in approximately 1.4 billion (31%) adults aged 30 to 79 years worldwide [3] and 108 million adults in the United States [4]. The prevalence of hypertension is rising globally owing to the aging of the population and an increase in the exposure to lifestyle risk factors [3] such as an unhealthy diet and sedentary lifestyle [5].
JMIR Cardio 2025;9:e76275
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According to the American Heart Association, high blood pressure, called hypertension, is defined as systolic blood pressure (SBP) ≥130 mm Hg or diastolic blood pressure ≥80 mm Hg that remains elevated across time [1]. Hypertension affects over 1.2 billion people worldwide [2] and, in the last decades, the number of people with hypertension has doubled [3]. Hypertension is a major risk factor for cardiovascular diseases such as heart attack and heart failure, stroke, and chronic kidney disease [4].
JMIR Mhealth Uhealth 2025;13:e68361
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Hypertension holds global significance as one of the most important modifiable risk factors for cardiovascular disease. Almost one-third of the global population is diagnosed with hypertension [1], which causes 7.5 million deaths annually, and its increasing prevalence has led to greater morbidity for the global population from its sequelae, such as heart disease [2,3].
JMIR Hum Factors 2025;12:e66176
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Diabetic nephropathy (DN), severe microvascular complications of diabetes, primarily manifests as proteinuria, hypertension, and a progressive decline in renal function, potentially leading to end-stage renal disease.
JMIR Med Inform 2025;13:e64979
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Hypertension is an independent and significant contributor to cognitive impairment; it increases the risk of MCI by 1.62 times. From 2007 to 2011, the prevalence of hypertension with MCI (HTMCI) was 16.5% [3]; meanwhile, a meta-analysis published in 2023 showed that the overall prevalence of HTMCI in China was 37.6% [4]. Evidence suggests that hypertension can increase the risk of cognitive-related diseases, such as Alzheimer disease (AD) and vascular dementia [5].
JMIR Res Protoc 2025;14:e70876
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Hypertension is a leading risk factor for cardiovascular disease worldwide [1]. It is estimated that hypertension affects approximately 31% of the global adult population [2] and a similar proportion of people in Singapore, an island state in Southeast Asia [3]. Despite this high prevalence, approximately half of those affected are unaware of their condition [3,4].
JMIR Res Protoc 2025;14:e72942
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Self-monitoring of diseases with support from patients’ health care providers is crucial in managing many chronic conditions and their risk factors, such as hypertension [1-3]. International guidelines on hypertension recommend self-monitoring of home blood pressure (HBP) for diagnosing and monitoring of hypertension because self-monitoring is widely accessible, cost-effective, and easy to use [4].
J Med Internet Res 2025;27:e75551
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For instance, these factors have been linked to dietary sodium intake [4-11], a major contributor to hypertension and cardiovascular disease development [12,13]. However, concentrating solely on these broad participant characteristics of underrepresented groups may overlook the influence of community-level differences on health outcomes, as women, Black individuals, or older patients from one community may differ from those of similar backgrounds in another.
JMIR Cardio 2025;9:e71343
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This study would address this gap with the use case of patients with hypertension within the Primary Technology Enhanced Care for Hypertension Program (PTEC-HT) in Singapore [8].
PTEC-HT was developed to integrate telehealth solutions for hypertension management, emphasizing remote blood pressure (BP) monitoring, care team support through remote monitoring and follow-up teleconsultations, and medication adjustments based on clinical guidelines.
J Med Internet Res 2025;27:e74051
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