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Neural Mechanism of Cognitive Reserve in Acupuncture Stimulation: Protocol for a Randomized, Placebo-Controlled Functional Near-Infrared Spectroscopy Trial

Neural Mechanism of Cognitive Reserve in Acupuncture Stimulation: Protocol for a Randomized, Placebo-Controlled Functional Near-Infrared Spectroscopy Trial

In contrast, functional near-infrared spectroscopy (f NIRS) has been suggested as an alternative tool for functional neuroimaging. f NIRS is an optical neuroimaging technique that allows the measurement of changes in brain tissue concentrations of oxyhemoglobin (Hb O2), deoxyhemoglobin (Hb R), and total hemoglobin (Hb T) within the brain, achieved by irradiating the head with near-infrared (NIR) light [11,12].

Hyeonsang Shin, Woohyun Seong, Yeonju Woo, Joo-Hee Kim, Kwang-Rak Park, Dong Hyuk Lee

JMIR Res Protoc 2025;14:e66838

The Effectiveness of a Digital App for Reduction of Clinical Symptoms in Individuals With Panic Disorder: Randomized Controlled Trial

The Effectiveness of a Digital App for Reduction of Clinical Symptoms in Individuals With Panic Disorder: Randomized Controlled Trial

As brain imaging technology advances, a great deal of functional mapping information on the human brain has been accumulated from positron emission tomography (PET), functional magnetic resonance imaging (f MRI), and functional near-infrared spectroscopy (f NIRS). Among these technologies, f NIRS can measure brain activity in a noninvasive and safe manner through measuring changes in the hemoglobin oxygenation state of the human brain [15].

KunJung Kim, Hyunchan Hwang, Sujin Bae, Sun Mi Kim, Doug Hyun Han

J Med Internet Res 2024;26:e51428

Risk, Trust, and Emotion in Online Pharmacy Medication Purchases: Multimethod Approach Incorporating Customer Self-Reports, Facial Expressions, and Neural Activation

Risk, Trust, and Emotion in Online Pharmacy Medication Purchases: Multimethod Approach Incorporating Customer Self-Reports, Facial Expressions, and Neural Activation

In the final part of the study, neural data were collected using the mobile neuroimaging method of functional near-infrared spectroscopy (f NIRS). In an event-related experimental paradigm, the online pharmacies were shown to participants as screenshots with the medications they had to search for in the first task.

Semra Ersöz, Anika Nissen, Reinhard Schütte

JMIR Form Res 2023;7:e48850

The Effects of Virtual Reality Treatment on Prefrontal Cortex Activity in Patients With Social Anxiety Disorder: Participatory and Interactive Virtual Reality Treatment Study

The Effects of Virtual Reality Treatment on Prefrontal Cortex Activity in Patients With Social Anxiety Disorder: Participatory and Interactive Virtual Reality Treatment Study

In this study, we examined changes and responses in brain frontal region activities using functional near-infrared spectroscopy (f NIRS). f NIRS can be used to examine the functional activity in certain areas of the brain by measuring changes in the concentrations of oxygenated hemoglobin (Hb O2) and deoxygenated hemoglobin (Hb R) in brain tissue to assess neurological activation. f NIRS is safe, portable, and easy to use compared with neuroimaging tools such as functional magnetic resonance imaging (f MRI) [30].

Hojun Lee, JongKwan Choi, Dooyoung Jung, Ji-Won Hur, Chul-Hyun Cho

J Med Internet Res 2021;23(12):e31844

Getting to the Root of Fine Motor Skill Performance in Dentistry: Brain Activity During Dental Tasks in a Virtual Reality Haptic Simulation

Getting to the Root of Fine Motor Skill Performance in Dentistry: Brain Activity During Dental Tasks in a Virtual Reality Haptic Simulation

In related work, examining neural activity during surgery, Ohuchida et al [25] used functional near-infrared spectroscopy (f NIRS) to demonstrate that trainees with no experience of an endoscopy task had higher oxyhemoglobin demands in the frontal cortex of the brain than expert surgeons. f NIRS is a technique that uses a series of near-infrared light sources and detectors across the surface of the scalp to measure levels of oxygenated and deoxygenated blood in specific regions of the brain.

Suzanne Perry, Susan M Bridges, Frank Zhu, W Keung Leung, Michael F Burrow, Jamie Poolton, Rich SW Masters

J Med Internet Res 2017;19(12):e371