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Efficacy and Compliance of a Working Memory Multitasking Task Mobile Intervention for Children With Attention-Deficit/Hyperactivity Disorder: Single-Arm, Pre-Post Pilot Study

Efficacy and Compliance of a Working Memory Multitasking Task Mobile Intervention for Children With Attention-Deficit/Hyperactivity Disorder: Single-Arm, Pre-Post Pilot Study

Through this study, we aimed to provide preliminary evidence supporting the efficacy and acceptability of Star Ruckus as a DTx. Two cohorts, 1 taking medication and 1 without medication, were included in the study. The participants in both cohorts agreed not to alter their medication status during the study, understanding that any change could result in their withdrawal.

Minyoung Jung, Jimin Woo, Sung Jin Kim, You Bin Lim, Younglae Kim, Dongwon Kang, Jung-sang Min, Bung-Nyun Kim

JMIR Hum Factors 2025;12:e70479


Efficacy of Fuzheng Quxie Formula Against Postoperative Metastasis of Lung Cancer in Stage IIA-IIIA With Negative Driver Genes: Protocol for a Multicenter, Double-Blind, Randomized Controlled Trial

Efficacy of Fuzheng Quxie Formula Against Postoperative Metastasis of Lung Cancer in Stage IIA-IIIA With Negative Driver Genes: Protocol for a Multicenter, Double-Blind, Randomized Controlled Trial

Therefore, in response to the urgent clinical needs of postoperative patients with IIA-IIIA NSCLC who are negative for driver gene expression, we attempted to objectively evaluate the efficacy of Fuzheng Quxie Formula in inhibiting metastasis of IIA-IIIA NSCLC who are negative for driver gene expression and safety. This study will be the first trial to evaluate the efficacy and safety of Fuzheng Quxie Formula in inhibiting metastasis after surgery in stage IIA-IIIA lung cancer with negative driver genes.

Fan Xu, Yun Yang, Yinbin Luo, Bin Luo, Jialiang Yao, Yiyang Zhou, Minghua Li, Jianchun Wu, Wenfei Shi, Lei Jiang, Qian Huang, Wentao Fang, Zhihong Fang, Yan Li, Jianhui Tian

JMIR Res Protoc 2025;14:e66342


Efficacy of Telemedical Interventional Management in Patients with Coronary Heart Disease Undergoing Percutaneous Coronary Intervention: Randomized Controlled Trial

Efficacy of Telemedical Interventional Management in Patients with Coronary Heart Disease Undergoing Percutaneous Coronary Intervention: Randomized Controlled Trial

Emerging technologies, such as web-based remote patient management systems, have demonstrated efficacy in promoting better self-management by providing health education and facilitating interactions between patients and health care providers [10].

Xiaofan Yu, Jiaoyu Cao, Jie Xu, Qizhi Xu, Hongwu Chen, Dongbiao Yu, Anping Ou, Yue Hu, Likun Ma

J Med Internet Res 2025;27:e63350


Efficacy and Safety of Acupuncture at Sensitized Acupoints for Knee Osteoarthritis: Protocol for a Multicenter, Single-Blind Randomized Controlled Trial

Efficacy and Safety of Acupuncture at Sensitized Acupoints for Knee Osteoarthritis: Protocol for a Multicenter, Single-Blind Randomized Controlled Trial

Although several randomized controlled trials (RCTs) have explored the efficacy of acupuncture for KOA [25,27-29], their limitations preclude definitive conclusions. For instance, they used shallow needling as a sham acupuncture control, despite evidence that shallow needling may produce substantial therapeutic effects [30].

Zenan Wu, Zehao Hu, Zixuan Xu, Tao Xiao, Qiuxuan Huang, Xu Zhou, Haifeng Zhang, Yong Fu

JMIR Res Protoc 2025;14:e77336


Outcomes of an App-Based Intervention to Target Naming Among Individuals With Poststroke Aphasia: Virtual Randomized Controlled Trial

Outcomes of an App-Based Intervention to Target Naming Among Individuals With Poststroke Aphasia: Virtual Randomized Controlled Trial

The purpose of this study is to report the efficacy of a beta version of the Voice Adapt app, within a randomized controlled trial (RCT; Clinical Trials.gov NCT04108364). Specifically, we examined the impact of training with the Voice Adapt app on language and communication outcomes in individuals with chronic aphasia. Primary outcomes were naming ability, and secondary outcomes included measures of overall language, communication effectiveness, and quality of life.

Esther S Kim, Laura Laird, Carlee Wilson, Steven Stewart, Philip Mildner, Sebastian Möller, Raimund Schatz, Robert P Spang, Jan-Niklas Voigt-Antons, Elizabeth Rochon

JMIR Mhealth Uhealth 2025;13:e67711


Efficacy of Tuina Versus the Proprioceptive Neuromuscular Facilitation (PNF) Technique in Patients With Nonspecific Chronic Neck Pain: Protocol for a Randomized Controlled Trial

Efficacy of Tuina Versus the Proprioceptive Neuromuscular Facilitation (PNF) Technique in Patients With Nonspecific Chronic Neck Pain: Protocol for a Randomized Controlled Trial

Current Western medical approaches, including nonsteroidal anti-inflammatory drugs and physical therapy, often provide short-term relief but show limited long-term efficacy due to high recurrence rates [10]. As a result, nonpharmacological approaches have gained increasing attention, with exercise therapy considered an effective method for pain relief [11].

Kaiqi Fan, Aicheng Wang, Hainan Gao, Ting Yu, Xiangyu Zhu

JMIR Res Protoc 2025;14:e63528


Automatic Image Recognition Meal Reporting Among Young Adults: Randomized Controlled Trial

Automatic Image Recognition Meal Reporting Among Young Adults: Randomized Controlled Trial

However, manually entering dietary intake information poses significant usability challenges for m Health app users [24], potentially resulting in inaccurate or incomplete reporting, and thus undermining the efficacy of managing healthy eating habits [16]. This raises an urgent need to minimize the operational loading of users [25,26], as the ease and effectiveness of food data entry methods have a direct and significant impact on the usability of dietary tracking applications [23].

Prasan Kumar Sahoo, Sherry Yueh-Hsia Chiu, Yu-Sheng Lin, Chien-Hung Chen, Denisa Irianti, Hsin-Yun Chen, Mekhla Sarkar, Ying-Chieh Liu

JMIR Mhealth Uhealth 2025;13:e60070


Digital Interventions and Mental Health Outcomes in Patients With Cancer: Systematic Review and Meta-Analysis

Digital Interventions and Mental Health Outcomes in Patients With Cancer: Systematic Review and Meta-Analysis

In the preliminary stage of this review, mental health outcomes were broadly defined to include not only clinical measures of psychological symptoms (eg, depression, anxiety, distress, and stress), but also psychological well-being (eg, quality of life and emotional functioning) and psychological resources (eg, self-efficacy and resilience).

Zixuan Wu, Feifei Luo, Siyuan Wang, Xinyu Hu, Meifang Chen

JMIR Cancer 2025;11:e64754


Effects of Information Length and Implementation Intentions on Adherence to Weight Management Strategies: Experimental Study

Effects of Information Length and Implementation Intentions on Adherence to Weight Management Strategies: Experimental Study

While the efficacy of many of these interventions is well-established [5], their impact on weight management remains contingent upon individual adherence. However, evidence shows that adherence is often suboptimal and can be as low as 10%, undermining intervention effectiveness [6]. There is also some evidence that adherence is lower in individuals with lower socioeconomic status [7], which may contribute to health inequalities.

Khaleda Ahmadyar, Joanna Szypula, Angeliki Bogosian, Katy Tapper

JMIR Mhealth Uhealth 2025;13:e65260